Divergent lymphocyte associations with depression severity and case status in first-episode, drug-naive adolescents: A multicenter study

Figure 1 Flowchart of the study design and subject screening procedure.

Figure 2 Dunn’s test for multiple comparison between immune markers. ^aP < 0.05. LNR: Lymphocyte-to-neutrophil ratio; NMR: Neutrophil-to-monocyte ratio; LMR: Lymphocyte-to-monocyte ratio.

Figure 3 Ordered logistic regression analysis. A: Ordered logistic regression analysis, adjusted for age and sex; B: Ordered logistic regression analysis between sexes. ^aP < 0.05. LNR: Lymphocyte-to-neutrophil ratio; NMR: Neutrophil-to-monocyte ratio; LMR: Lymphocyte-to-monocyte ratio; OR: Odds ratio; CI: Confidence interval.

Figure 4 Receiver operating characteristic curve analysis of inflammation indicators for predicting depression in adolescents. ROC: Receiver operating characteristic; AUC: Area under the curve; CI: Confidence interval; NMR: Neutrophil-to-monocyte ratio; LMR: Lymphocyte-to-monocyte ratio.