Psychological distress in advanced non-small cell lung cancer: Impact on targeted therapy and quality of life

doi:10.5498/wjp.122462

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Oct 19, 2026; 16(10): 122462
Published online Oct 19, 2026. doi: 10.5498/wjp.122462

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Figure 1 Flow chart of this study. EORTC QLQ-C30: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30.

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Figure 2 Comparison of objective response rate and disease control rate of targeted combination therapy between the psychological distress group and the non-psychological distress group. A: Targeted combination therapy in non-small cell lung cancer with psychological distress patients; B: Targeted combination therapy in non-small cell lung cancer with non-psychological distress patients. NSCLC: Non-small cell lung cancer; ORR: Objective response rate; DCR: Disease control rate; PR: Partial response; SD: Stable disease; PD: Progressive disease.

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Figure 3 Comparison of objective response rate and disease control rate of targeted combination chemotherapy between the psychological distress group and the non-psychological distress group. A: Targeted-therapy combination chemotherapy in non-small cell lung cancer with psychological distress patients; B: Targeted-therapy combination chemotherapy in non-small cell lung cancer with non-psychological distress patients. NSCLC: Non-small cell lung cancer; ORR: Objective response rate; DCR: Disease control rate; PR: Partial response; SD: Stable disease; PD: Progressive disease.

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Figure 4 Progression-free survival of the patient receiving treatment. A: Targeted comprehensive therapy; B: Targeted combination chemotherapy.

Citation: Chen WJ, Hu XY, Yao SB, Chen MX, Bi ZR, Cheng HD. Psychological distress in advanced non-small cell lung cancer: Impact on targeted therapy and quality of life. World J Psychiatry 2026; 16(10): 122462
URL: https://www.wjgnet.com/2220-3206/full/v16/i10/122462.htm
DOI: https://dx.doi.org/10.5498/wjp.122462

Chen WJ, Hu XY, Yao SB, Chen MX, Bi ZR, Cheng HD. Psychological distress in advanced non-small cell lung cancer: Impact on targeted therapy and quality of life. World J Psychiatry 2026; 16(10): 122462 [DOI: 10.5498/wjp.122462]

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