Do serum biomarker levels correlate with anxiety disorders?

Figure 1 Diagnostic performance of serum biomarkers in anxiety disorder with a history of violence. A: Receiver operating characteristic (ROC) analysis yielded the characteristic curves for the diagnostic performance of brain-derived neurotrophic factor (BDNF) precursor, aquaporin-4, and glycogen synthase kinase-3β; B: ROC analysis yielded the characteristic curves for the diagnostic performance of BDNF, mature BDNF, and the combined diagnosis biomarker. AQP4: Aquaporin-4; GSK3β: Glycogen synthase kinase-3β; BDNF: Brain-derived neurotrophic factor; mBDNF: Mature brain-derived neurotrophic factor; proBDNF: Brain-derived neurotrophic factor precursor.

Figure 2 Correlations of serum biomarkers in anxiety disorder with a history of violence. A: Correlation between brain-derived neurotrophic factor (BDNF) and mature BDNF (mBDNF) levels; B: Correlation between BDNF and BDNF precursor (proBDNF) levels; C: Correlation between mBDNF and proBDNF levels. BDNF: Brain-derived neurotrophic factor; mBDNF: Mature brain-derived neurotrophic factor; proBDNF: Brain-derived neurotrophic factor precursor.