Cumulative effects of stress-sensitivity factors on depressive symptoms and suicide risk: A prospective study

Figure 1 The proportion of stress-sensitivity factors in patients with major depressive disorders. A: The proportion of patients with high- or low-level stress-sensitivity factors; B: The proportion of patients with different numbers of high-level stress-sensitivity factors; C: Venn diagram revealing the overlap between high-level stress-sensitivity factors in patients. PSS: Perceived Stress Scale; T-AI: Trait Anxiety Inventory of State-Trait Anxiety Inventory; S-AI: State Anxiety Inventory of State-Trait Anxiety Inventory.

Figure 2 Gradual increase in severity of clinical manifestations at baseline with an increasing number of high-level stress-sensitivity factors in patients with major depressive disorders. The P values are obtained from the analysis of variance with linear trend analysis. All P < 0.001. Error bars represent the 95% confidence intervals. HAMD-17: 17-item Hamilton Depression Scale; HAMA: Hamilton Anxiety Scale; BSSI: Beck Scale for Suicide Ideation; SDS: Sheehan Disability Scale; PDQ-5: Perceived Deficits Questionnaire five-item version.