Functional near-infrared spectroscopy in elderly patients with four types of dementia

Figure 1 Diagrammatic sketch of localization of the functional near-infrared spectroscopy probe set over left and right frontotemporal cortex. A: Anterior view; B: Lateral view; C: Probe arrangement. Blue circle: Detectors; Purple circle: Light source.

Figure 2 Comparison of functional near-infrared spectroscopy patterns and task performances during the verbal fluency task (left) and the working memory task (right) between four types of dementia patients. A: Frontotemporal lobe dementia; B: Lewy body dementia; C: Parkinson’s disease dementia; D; Alzheimer’s disease. Red indicates higher activation, while blue indicates lower activation.

Figure 3 Resting state functional connections were calculated by conducting Pearson’s correlation analysis between the time series of every pair of measurement channels. A: Frontotemporal lobe dementia; B: Lewy body dementia; C: Parkinson’s disease dementia; D: Alzheimer’s disease. Red indicates higher activation, while blue indicates lower activation.