Cerebrotendinous xanthomatosis presenting with schizophrenia-like disorder: A case report

Figure 1 Imaging of left ankle joint and histopathological analysis of the resected specimen. A: Histological findings of left Achilles tendon xanthoma shows foamy macrophages (arrowheads) and lipid crystal (arrows); B: Left ankle joint magnetic resonance imaging reveals a mild increase in signal intensity on the proton density-weighted image, accompanied by linear hypointensity within.

Figure 2 Brain imaging findings. A: Brain magnetic resonance imaging reveals patchy symmetrical abnormal signals in the dentate nuclei and deep medulla of bilateral cerebellar hemispheres and a slight decrease in signal intensity on T1 weighted image; B: Slight increase in signal intensity on fluid attenuated inversion recovery; C: Magnetic resonance spectroscopy shows right cerebellar dentate nuclei; D: Decreases in N-acetylaspartate intensities and increases in lactate signals and lipid signals.