Branded as 'the sport of fitness', CrossFit is well known for its physical benefits, but the benefits may extend far beyond general fitness. Through the lens of positive psychology, we focused on a global CrossFit community to examine the potential psychological and workplace benefits behind this popular exercise program. Results showed that the frequency of CrossFit participation each week significantly predicted well-being and positive Psychological Capital (PsyCap). Additionally, both well-being and PsyCap mediated the relationship between weekly frequency and employee engagement. Our findings show support for benefits in frequent weekly CrossFit participation that reach far beyond physical health. This research underscores CrossFit's multifaceted benefits and encourages organizations to incorporate CrossFit into employee wellness initiatives. It also paves the way for further exploration into the complex impacts of physical fitness on psychological and organizational health.

This study aims to explore the impact of physical exercise on university students' life satisfaction and analyses the chain mediation effect of general self-efficacy and health literacy, providing empirical reference and theoretical foundation for the comprehensive enhancement and optimization of students' mental health.

Based on data from the "China University Student Physical Activity and Health Tracking Survey" (CPAHLS-CS) 2024, the measurement scales used included the Physical Activity Rating Scale (PARS-3), the Satisfaction with Life Scale (SWLS), the General Self-Efficacy Scale (GSES), and the 9-item Short Form Health Literacy Scale (HLS-SF9). A total of 4575 valid samples were analyzed.

A significant positive correlation was found between physical exercise and life satisfaction (r = 0.137, P < 0.01). The total effect of physical exercise on university students' life satisfaction was significant, with an effect value of 0.045 (95%CI = [0.035, 0.054]). The chain mediation effect of general self-efficacy and health literacy in the relationship between physical exercise and life satisfaction was significant, with an effect value of 0.005 (95%CI = [0.004, 0.006]), accounting for 11.4% of the total effect. The direct effect of physical exercise on life satisfaction had a standardized regression coefficient of 0.001, which was not significant.

University students' life satisfaction is closely related to physical exercise, general self-efficacy, and health literacy. General self-efficacy and health literacy play a full mediating role in the effect of physical exercise on life satisfaction.

In recent years medical science and research are increasingly directed towards a holistic approach that considers health as global well-being rather than solely as the absence of disease. In this framework, lifestyle interventions and, in particular, physical exercise, are of crucial importance in prevention and treatment. Therefore, the purpose of this study is to describe this mutual interplay between physical behaviours, sarcopenia, and frailty, as well as to illustrate the role of structured exercise training in aging and disease.

Physical activity and exercise training are determinants of lifelong global wellness and healthy aging. On the contrary, sedentary behaviour and physical inactivity are strictly linked to frailty and pre-frailty, both in adults and the elderly, with or without chronic diseases. On the other hand, the presence of pathological conditions is associated with a more inactive and sedentary behaviour. The co-presence of these factors is characterized by a mutual causal exchange in which they are imbricated in a continuous mechanistic interplay that involves inflammation, sarcopenia, osteopenia, functional impairment and many other pathophysiological aspects that rapidly can lead to a status of frailty.

A sedentary lifestyle and physical inactivity critically affect alterations in body composition and loss in functional capacity, typically linked to aging and accelerated by chronic diseases. However, physical activity and exercise can counteract the onset of pre-frailty and frailty by conferring beneficial effects on the individual's overall well-being.

To analyze the effect of two 16-week interventions with jazz dance and concurrent training compared to a control group on anxiety, depression, stress, mood, and the perspective of aging in menopausal women, after 1-month, post-intervention, and at the 6-month follow-up.

70 post-menopausal women (53.19 ± 3.39 years) randomized into 3 groups:intervention group with Jazz Dance (JD); intervention group with Concurrent Training (CT), and Control Group (CG). Both interventions lasted 16 weeks, with 60-min classes, JD with a frequency of two weekly classes, and CT three times a week. The intensity of the JD was progressive and according to the frequency of beats per minute of the songs. In CT, the aerobic an initial intensity of 60% of HRmax, reaching 90%, and resistance the volume of sets and loads increased progressively throughout the intervention. Questionnaires related to symptoms of anxiety and depression (Hospital Anxiety and Depression Scale); stress (Perceived Stress Scale); mood (Brunel Mood Scale); and aging perspective (Sheppard Inventory) were applied. Intention-to-treat (ITT) and protocol adherence analysis were performed.

In the protocol analysis, the JD showed improvements in anxiety and depressive symptoms after 1-month, which remained at the follow-up. The TC presented reduced anxiety and depressive symptoms after 16 weeks, which also remained at the follow-up. Considering stress, the CT showed improvements at all times and the JD post-intervention. As for mood, the CT presented reduced anger, mental confusion, and fatigue only after 1-month, and both exercise groups presented increased vigor at all times.

Both interventions were beneficial, however dance showed immediate results for anxiety and depression, and concurrent training for stress. Considering mood, concurrent training was more effective for anger, mental confusion, and fatigue, while both interventions were effective for vigor.

Brazilian Clinical Trials Registry (REBEC) RBR - 87ndrv.

The benefits of physical activity (PA) for well-being are well known; however, studies examining longitudinal effects across diverse international samples in late adolescence are limited. This study advances prior work by combining a partial longitudinal design with a multinational sample to assess the predictive effect of PA on biennial change in older adolescents' well-being, while testing for sex differences. The sample included 903 adolescents (50.4% female) from nine countries, who completed The European Health and Behavior Survey at age 16 and the EPOCH Measure of Adolescent Well-Being at ages 16 and 18. Multilevel modeling estimated the average impact of PA on change in well-being, controlling for baseline well-being. To further interrogate the findings, an additional analysis tested the effect using relative difference scores of well-being to provide a direct measure of simple change. Meta-analytic techniques then captured the degree of cross-country consistency in the estimated effect. Results indicated that more PA at age 16 significantly predicted greater EPOCH well-being at age 18, controlling for prior well-being at age 16, and that adolescent sex did not moderate this effect. The relative difference score analysis confirmed these results. The meta-analysis revealed no significant heterogeneity in the predictive effect across countries. Findings extend previous research by demonstrating the cross-cultural consistency of PA benefits during a critical developmental transition period. They suggest that PA is a modifiable behavior that can be utilized globally to enhance adolescent well-being, though individual differences and context-specific factors should be considered in public health policies and interventions.

Vitamin D and magnesium are essential nutrients that play key roles in an athlete's performance, recovery, and overall health. Vitamin D is crucial for bone health (aiding calcium absorption and preventing stress fractures), muscle function (preventing weakness and injury), and reducing respiratory infections. Magnesium is fundamental in muscle function, adenosine triphosphate production for muscle contraction, electrolyte balance, bone strength, and cardiovascular health. The magnesium requirement of healthy adults is estimated at 300-400 mg/day, but there is evidence that athletes may have higher magnesium needs compared to sedentary persons. Magnesium and vitamin D are closely linked-vitamin D aids magnesium absorption, while magnesium is vital for vitamin D synthesis, transport, and activation. Given their importance in athletes, this article explores their functions, interactions, and the effects of deficiencies and supplementation in athletic populations.

Major depressive disorder (MDD) is prevalent worldwide and impacts the health and quality of life of millions of people. MDD is a condition influenced by a complex interplay of genetic, psychological and environmental factors. This narrative review examines the roles of stress vulnerability, resilience, and lifestyle habits in shaping the risk of depression, emphasizing holistic approaches that address both biological and environmental factors in mental health management. Vulnerability to stress, influenced by factors such as childhood adversity and personality traits such as neuroticism, increases the probability of MDD. On the other hand, resilience acts as a protective mechanism, reducing stress reactivity and supporting mental health. The main findings suggest that healthy lifestyle habits, including consistent sleep patterns, a balanced diet and regular exercise, play significant roles in increasing resilience and preventing depressive symptoms. Interventions to build resilience, such as emotional skills training and promoting a growth mindset, have been proven effective in reducing depressive symptoms. Overall, the findings suggest that lifestyle modifications combined with psychological strategies to build resilience can significantly reduce depressive disorders. This study advocates for personalized therapeutic strategies that consider the multifactorial nature of depressive disorders, integrating psychological and lifestyle interventions to enhance resilience and mental health.

A systematic evaluation and network meta-analysis (NMA) using randomized controlled trials (RCTs) was conducted to investigate the effects of different exercise intensities and dosages on the mental health of college students.

A systematic search of eight electronic databases of RCTs involving mental health exercise interventions for college students was conducted, which included data from the inception of the databases through July 2024. Two independent reviewers assessed the quality of the literature. Pairwise, network, and dose‒response meta-analyses were conducted via random-effects models to analyze the effects of exercise on college students' mental health.

A total of 48 RCTs (3951 patients) were included. Light, moderate, and vigorous exercise were all significantly effective at reducing symptoms of depression, anxiety and stress, whereas very light exercise was only effective at reducing symptoms of depression and stress. Surface under the cumulative ranking curve (SUCRA) probability ranking revealed that vigorous exercise had the highest probability of being the best intervention intensity to improve depression and stress symptoms, and the best exercise intensity to improve anxiety symptoms was moderate. The minimum threshold for overall exercise intervention for depressive symptoms was 150 METs-min per week, the benefits provided after doses above 1300 METs-min per week were less pronounced, and the predicted maximum significant response dose was 860 METs-min per week, which was the same as the predicted data for moderate exercise.

Very light, light, moderate, and vigorous exercise are all potentially effective exercise intensities for improving the mental health of college students, with no significant difference in effectiveness across the four exercise intensities. SUCRA rankings revealed that vigorous exercise is the most effective intervention for depression and stress and that moderate exercise is the most effective intervention for anxiety. Exercise interventions for depressive symptoms have a low dosage threshold, are simple and easy to administer, and are good treatments for psychological problems in college students.

This study aims to assess the effect of swim exercise along with consumption of bindii hydroalcoholic extract on memory and the oxidative stress markers in old male rats.

This study was conducted on 32 old (400-500 g) and eight young male Wistar rats. The groups included young, old, old bindii (200 mg/kg), old exercise, and old bindii exercise (concurrent swimming training). All interventions were performed within 14 days. The animals' spatial memory was evaluated by the Y maze, radial maze, and shuttle box, Oxidative stress factors were also measured.

Compared to the old control group, the bindii extract along with swimming exercise significantly increased the periodic behavior percentage in the Y maze and the delay time in entry into the dark chamber in the shuttle box but no significant difference was seen in the reference memory error in the radial maze. Also, a significant increase in the amount of catalase (CAT) and antioxidant capacity (TAC) and a significant decrease in the amount of malondialdehyde (MDA) were observed in all treatment groups.

These results show that exercise, along with the bindii extract consumption, can improve spatial and avoidance memory in old rats probably through the reduction of oxidative stress effects.

Appetite loss among older adults is common and may lead to malnutrition, reduced function and frailty. Regular physical activity may help regulate appetite and enhance overall wellbeing. However, evidence concerning the relationship between physical activity and appetite in older adults remains scarce.

This study aims to examine the existing literature for the relationship between appetite and physical activity among older adults, contributing to the identification of existing research gaps.

A scoping review was conducted using a block search strategy with keywords including physical activity, exercise, appetite, and older adults. Searches were performed in Web of Science, PubMed, and CINAHL on November 23, 2023. The inclusion criteria were: English language, human studies, population aged 55+ without severe disease, addressing both appetite and physical activity, original articles, and not qualitative studies.

Of 1190 articles identified, 25 were included. Females comprised 52% of the participants and most studies focused on community-dwelling older adults, primarily in the US and northern Europe. Research design and methodologies varied widely. Of the 25 studies, 14 were cross-sectional studies, seven randomized controlled trials, three non-randomized controlled trials, and one longitudinal observational study. Associations between physical activity and appetite were found in a longitudinal observational study including 186 participants, two randomized trials involving higher-intensity exercise, all non-randomized studies, and 10 cross-sectional studies.

Although an association between appetite and physical activity among older adults has been observed, the lack of randomized controlled trials limits conclusions regarding whether exercise can effectively regulate appetite in older adults.

Physical activity and social support are recognized as contributing to preventing depression. Community-based group exercises are activities that combines both functions. Fewer studies have examined the association between community-based group exercises and the depression severity of middle-aged and older adults. In this study, we were trying to estimate such correlation and explore the potential mechanisms. Data from the China Longitudinal Study of Health and Retirement was analyzed (N = 17,481). Participation in community-based group exercises and depression severity were self-reported by the surveyed middle-aged and older adults. The ordered probit model was used to analyze the association between participation in community-based group exercises and depression severity. Compared with middle-aged and older adults who did not participate in community-based group exercises, those who engaged in such activities exhibited improved depression severity in the current year (coefficient = 0.229, p < 0.01) and two years later (coefficient = 0.199, p < 0.01). The relationship was more pronounced among women. Improved physical fitness and more frequent visits to neighbors and relatives for social support are potential mechanisms. In addition to medical interventions, social support and physical fitness are effective strategies for depression prevention. Policymakers could enhance the mental health of middle-aged and older adults, particularly among women, by encouraging participation in community-based group exercises. This is particularly important in rapidly ageing societies.

Physical activity has gained attention in recent years as a promising intervention for improving the mental health of children and adolescents. However, evidence supporting the effectiveness of physical activity interventions for the mental health of typically developing children and adolescents remains limited.

This study conducted a comprehensive search across five electronic databases up to July 2024. Studies were eligible for inclusion if they involved an intervention with a control group that examined the effects of physical activity on the mental health of typically developing children and adolescents. Articles focusing on participants with developmental, behavioral, or psychiatric disorders were excluded. A random-effects meta-analysis was conducted using Stata 18.0. The quality of evidence and risk of bias were assessed using the GRADE framework and the PEDro scale.

The initial search yielded 27,527 articles, of which 30 met the inclusion criteria. Meta-regression analysis indicated that country and intervention frequency were significant sources of heterogeneity. Physical activity interventions were significantly more effective than the control group in improving mental health (SMD = 0.37, 95% CI: 0.20 to 0.53). These interventions showed particularly strong effects on stress reduction (SMD = 0.86, 95% CI: 0.15 to 1.56) and social competence enhancement (SMD = 0.56, 95% CI: 0.07 to 1.06). Moreover, physical activity interventions were notably more effective for male adolescents (SMD = 1.11, 95% CI: 0.34 to 1.88) and those at the secondary school level (SMD = 0.45, 95% CI: 0.23 to 1.69).

Physical activity is beneficial in improving various aspects of mental health, including anxiety, depression, stress, self-esteem, and social competence in typically developing children and adolescents. However, the quality of evidence in this study is low due to methodological limitations of the studies included in this review. More high-quality randomized controlled trials are needed to validate these findings. Teachers and community workers can leverage physical activity as a preventive strategy to promote the mental health of children and adolescents. Future research should also investigate how factors like socioeconomic status and the sporting environment impact the effectiveness of these interventions.

PROSPERO, CRD42024567153.

Mental health issues among university students are increasingly prominent, and effective interventions are urgently needed. Physical exercise has shown potential in improving mental health, but the underlying mechanisms remain unclear. Based on the Conservation of Resources (COR) theory and the Dual - Factor Model of Mental Health, this study aims to explore the dual impact of physical exercise on university students' mental health and the chain - mediating effects of mindfulness and psychological resilience.

A cross-sectional survey was carried out on 720 students from Chinese universities. Validated instruments were used to measure physical exercise, mindfulness, resilience, and mental health outcomes. SPSS 27.0 and Mplus 8.3 were employed for data analysis, including descriptive statistics, correlation analysis, confirmatory factor analysis, and mediation effect testing.

The findings show that physical exercise is a proactive resource investment behavior. It significantly enhances students' mindfulness and resilience. These psychological resources promote positive mental health indicators such as life satisfaction and positive affect, and at the same time, reduce negative factors like psychological distress. The chain mediation analysis indicates that mindfulness and resilience act as interconnected resources, which is in line with the "gain spiral" and "resource caravan" effects in the COR theory.

This study provides novel insights by demonstrating how mindfulness and resilience sequentially amplify the psychological benefits of physical exercise. It offers a more detailed understanding of the mechanisms behind the improvement of university students' mental health. The results have significant theoretical and practical implications, advocating for the integration of exercise, mindfulness, and resilience-building strategies in mental health interventions for university populations.

The prevalence of sleep disorders and anxiety is on the rise among high-stress groups like graduate students. Physical activity interventions have revealed effectiveness in improving mental health, yet the effect of specialized badminton training on sleep-disordered populations remains under-researched. Besides, the effects of various forms of badminton training on sleep quality and anxiety in graduate students vary.

Our study aims to evaluate the effect of basic skill, advanced skill, and physical conditioning-focused badminton training on sleep quality, anxiety levels, and baseline physiological markers in graduate students with sleep disorders.

A randomized controlled trial (RCT) was conducted (Clinical Registry Number: TCTR20250119001, 16 January 2025), involving 160 graduate students randomly assigned to one of four groups: Badminton Basic Skills Training Group (BBSTG), Badminton Advanced Skills Training Group (BASTG), Badminton Specialized Physical Training Group (BSPTG), and a Control Group (CG), with 40 participants per group. The experimental groups trained three times weekly for one hour per session over 12 weeks, while the CG received only standard lifestyle guidance. Repeated measurements of sleep quality and anxiety levels were assessed at baseline, 4, 8, and 12 weeks using the Pittsburgh Sleep Quality Index (PSQI) and Self-Rating Anxiety Scale (SAS), with resting heart rate and blood pressure also recorded at each time point.

(i) Baseline Measurements: Prior to the intervention, no statistically significant differences were uncovered among groups in terms of sleep quality, anxiety levels, basic physiological data (resting heart rate, blood pressure), or general characteristics (age, height, weight, BMI) (p > 0.05). Attrition rates of 8%- 11% were observed across groups, causing final group sizes of 36, 37, 35, and 36 for BBSTG, BASTG, BSPTG, and CG, respectively. This attrition had minimal impact on statistical analysis. (ii) PSQI Scores: Sleep quality enhanced significantly across all experimental groups over the 12-week period, with the BSPTG group showing the greatest improvement. At week 12, the BSPTG's PSQI score was 5.8 ± 0.8, significantly better than that of the CG (p < 0.001, 95% CI [- 2.7, - 1.4]). The BSPTG consistently outperformed the control group at all time points, with an F-value of 10.32 at week 12 (p < 0.001), stressing the positive effect of badminton training on sleep quality. (iii) SAS Scores: At week 12, the BSPTG's SAS score was 36.3 ± 4.0, significantly lower than that of the CG (p < 0.001, 95% CI [- 6.1, - 3.2]). Anxiety levels reduced significantly across all experimental groups, with the BSPTG demonstrating the most notable reduction, further illustrating the significant effect of physical conditioning training on anxiety relief. (iv) Resting Heart Rate and Blood Pressure: Resting heart rate reduced significantly over the 12-week period, with the BSPTG achieving a final rate of 66.1 ± 4.8, significantly better than that of the CG (p < 0.001, 95% CI [- 6.9, - 3.2]). While blood pressure displayed some reduction post-intervention, differences were not statistically significant (p > 0.05), revealing limited short-term effect of badminton training on blood pressure. (v) Effect Sizes (Cohen's d): In PSQI scores, BSPTG showed a large effect (d = 0.8), BASTG a medium effect (d = 0.5), and BBSTG a small effect (d = 0.3). For SAS scores, BSPTG demonstrated a medium-to-large effect (d = 0.7), BASTG a medium effect (d = 0.5), and BBSTG a small effect (d = 0.3). In resting heart rate, BSPTG showed the most significant improvement (d = 0.6), with BASTG showing a small-to-medium effect (d = 0.4) and BBSTG showing minimal improvement. Effect sizes for blood pressure were not significant.

Specialized badminton training, in detail, physical conditioning training, can significantly improve sleep quality and reduce anxiety levels in graduate students with sleep disorders and decrease resting heart rate. As a non-pharmacological intervention, specialized badminton training has underlying applications for enhancing mental health and cardiovascular health.

Randomized Controlled Trials, TCTR20250119001, 16 January 2025.

Subthreshold depression is common in primary care and is associated with significant healthcare burden. There is emerging evidence for the benefits of Exercise can reduce depressive symptoms among people with diagnosed depression, but there is limited evidence for subthreshold depression in primary care setting. This study aims to examine the efficacy of a 12-week online instructor-led exercise intervention in reducing depressive symptoms among people with subthreshold depression in primary care, when compared to usual care control.

This 1:1 randomised controlled trial will enrol 260 participants with subthreshold depression randomizing into 2 groups (online exercise intervention versus usual care control). The intervention consists of twice-weekly 1-h exercise online classes over 12 weeks, which will be led by certified instructors. Data will be collected at baseline (T0), immediate post intervention (T1), 3-month post intervention (T2) and 9-month post intervention (T3). The primary outcome is depressive symptoms measured by the Chinese version of Beck Depression Inventory-II (BDI-II) at T1. Secondary outcomes include anxiety symptoms, quality of life, physical activity levels, feasibility and acceptability, medication use and health service utilization, and cost assessment. Intention-to-treat analysis will be performed.

The proposed study will assess the efficacy of online exercise intervention in improving subthreshold depressive symptoms in primary care. The findings will inform clinicians and policy makers concerning prevention of depression in primary care, and may lead to changes in the respective current guidelines and public policies.

This trial has been registered in the Chinese Clinical Trial Registry, with the registration number: ChiCTR2400087923. The date of registration is 2024-08-07.

To evaluate the quality of life (QOL) of postmenopausal women during the COVID-19 pandemic in Thailand and the associated factors.

A cross-sectional study using a validated Thai version of the WHOQOL-BREF questionnaire to assess QOL was conducted.

A total of 453 postmenopausal women participated in the study, with a median age of 58 years (ranging from 41 to 65). These women, residing in urban areas of Thailand such as Bangkok, Nonthaburi, Nakhon Pathom, Pathum Thani, Samut Prakan, and Samut Sakhon, completed a survey questionnaire with the assistance of health volunteers during the COVID-19 pandemic, between October 2021 and April 2022. The study revealed that 55.85% of participants reported experiencing poor quality of life (QOL) during the pandemic. Stepwise logistic regression analysis identified several significant associations with QOL. Factors linked to a poorer QOL included lower levels of well-being index (odds ratio [OR] 7.89, 95% confidence interval [CI] 3.16-19.75, P < 0.01), reduced physical activity (OR 2.72, 95% CI 1.62-4.54, P < 0.01), and the severity of menopausal symptoms (OR 1.94, 95% CI 1.42-2.66, P < 0.01). Conversely, higher education (OR 0.28, 95% CI 0.10-0.75, P < 0.01), an earlier onset of menopause (OR 0.55, 95% CI 0.39-0.78, P < 0.01), and occasional social alcohol consumption (OR 0.56, 95% CI 0.33-0.94, P = 0.03) were identified as protective factors for QOL.

These findings highlight the importance of comprehensive menopausal care, addressing both physical and mental well-being, and providing specific care for menopausal symptoms during challenging times of the COVID-19 pandemic.

Repetitive negative thinking (RNT) is characterized by its persistence, difficulty in control, and the tendency to focus on negative thoughts and past events. It is recognized as a key factor in the development and maintenance of mental health issues such as depression and anxiety. A growing body of research suggests that physical activity-based interventions may effectively reduce RNT. However, the extent of this effect and the mechanisms behind it remain inconsistent across studies.

This systematic review synthesized evidence from 19 peer-reviewed studies retrieved from PubMed, Web of Science, and other relevant databases up to December 2024. The objective was to investigate the efficacy of physical activity-based interventions in reducing RNT, with a particular focus on the influence of intervention type, duration, frequency, and intensity.

The review found that physical activity interventions effectively reduce RNT, particularly when combined with psychological training. Combined interventions yielded greater reductions than physical activity alone. Moderate-to-high intensity exercise (30-60 min/session, 3-5 times/week) over an extended period was most effective, likely due to physiological, psychological, and social mechanisms. Single-session interventions showed limited effects, emphasizing the need for sustained engagement. Notably, interventions were more effective in individuals with depression, anxiety, or chronic stress, whereas effects in healthy individuals were smaller and more variable, suggesting that baseline symptomatology enhances intervention benefits.

This review underscores the importance of designing intervention protocols that integrate both physical and psychological components to achieve greater reductions in RNT. The findings provide empirical support for the use of combined interventions involving physical activity and psychological training as an effective strategy for managing RNT. Additionally, future research should prioritize identifying optimal intervention characteristics (e.g., type, frequency, intensity) and addressing methodological limitations, such as the inclusion of diverse participant samples and broader language coverage, to provide more comprehensive insights into effective intervention strategies. These findings have important implications for mental health interventions and offer practical guidance for developing evidence-based approaches to reduce RNT.

To summarize the characteristics, estimate the efficacy of multicomponent structured exercise (MSE) intervention on older adults' depression, and investigate its potential moderators.

MEDLINE, PubMed, PsycINFO, SPORTDiscus, Web of Science and Embase databases were searched from January 1, 2000 to June 1, 2024. Randomized controlled trials (RCTs) that included MSE intervention with aerobic, resistance and balance components targeting older adults, and reported depression as an outcome were selected. Random-effects meta-analyses were used to calculate effect sizes from the standardized mean difference (SMD) and 95 % confidence intervals (CIs). Meta-regression was conducted to identify the potential moderators.

Data were extracted from 19 studies (22 comparisons) with 1763 older adults. MSE showed a significant intervention effect on buffering older adults' depression (SMD, -0.49; 95 % CI, -0.84 to -0.14) but with considerable heterogeneity (I2 = 92 %) and low certainty of evidence. In subgroup analyses, MSE with unhealthy status participants, intervention duration of 12-24 weeks, over 2 times/week intervention frequency, equipment used and ≥ 80 % retention rate showed significant effects on improvement of older adults' depression. Intervention frequency (β, -0.83; 95 % CI, -1.50 to -0.16) and retention rate (β, 0.80; 95 % CI, 0.05 to 1.56) were identified as moderators.

MSE significantly improved older adults' depression. The findings highlighted the importance of intervention frequency and retention rate in enhancing MSE effectiveness. More high quality RCTs are required to explore and optimize the intervention strategies and dosages of MSE to extend the application in the prevention and treatment of geriatric depression.

To examine the influence of postpartum exercise on maternal depression and anxiety.

Systematic review with random effects meta-analysis and meta-regression.

Online databases up to 12 January 2024, reference lists, recommended studies and hand searches.

Randomised controlled trials (RCTs) and non-randomised interventions of any publication date or language were included if they contained information on the Population (postpartum people), Intervention (subjective or objective measures of frequency, intensity, duration, volume, type, or mode of delivery of exercise), Comparator (no exercise or different exercise measures), and Outcome (postpartum depression, anxiety prevalence, and/or symptom severity).

A total of 35 studies (n=4072) were included. Moderate certainty evidence from RCTs showed that exercise-only interventions reduced the severity of postpartum depressive symptoms (19 RCTs, n=1778, SMD: -0.52, 95% CI -0.80 to -0.24, I2=86%, moderate effect size) and anxiety symptoms (2 RCTs, n=513, SMD: -0.25, 95% CI -0.43 to -0.08, I2=0%, small effect size), and the odds of postpartum depression by 45% (4 RCTs, n=303 OR 0.55, 95% CI 0.32 to 0.95, I2=0%) compared with no exercise. No included studies assessed the impact of postpartum exercise on the odds of postpartum anxiety. To achieve at least a moderate reduction in the severity of postpartum depressive symptoms, postpartum individuals needed to accumulate at least 350 MET-min/week of exercise (eg, 80 min of moderate intensity exercise such as brisk walking, water aerobics, stationary cycling or resistance training).

Postpartum exercise reduced the severity of depressive and anxiety symptoms and the odds of postpartum depression.

The objective of this review study is to examine the combined antidepressant effects of exercise and polyphenol supplementation, with a focus on specific polyphenolic compounds such as crocin, curcumin, and quercetin, as well as different forms of physical exercise, including aerobic and resistance training. The research examines how these interventions influence depressive-like behaviors, cognitive function, and neurochemical markers in animal models and human participants. The findings demonstrate that both exercise and polyphenols independently contribute to mood enhancement, reduced anxiety, and improved cognitive function through mechanisms such as neurogenesis, neurotransmitter modulation, and anti-inflammatory effects. Notably, the combined interventions showed a synergistic effect, providing more significant benefits in reducing symptoms of depression and anxiety, enhancing cognitive performance, and supporting overall mental well-being. These results suggest that integrating exercise and polyphenol supplementation could be a promising non-pharmacological approach to managing depression and related disorders.

Depression is one of the most common mental disorders, with high rates of disability, particularly among women.

To explore the effects of suggestion therapy on anxiety, mood, and sleep-quality in middle-aged women with depression treated with escitalopram.

Overall, 102 female patients with depression aged 35-49 years were divided into control and experimental groups. The control group received oral escitalopram therapy, starting at a dose of 5 mg/day, which was gradually increased to 10-20 mg/day after 1 week for a total of 8 weeks. The experimental group received the suggested therapy based on the control group. The Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), Profile of Mood States-Short Form, and Pittsburgh Sleep Quality Index (PSQI) were used to assess depression, anxiety, mood status, and sleep quality.

Before treatment, there were no significant differences in the SDS, SAS, Profile of Mood States, and PSQI scores between the two groups (P > 0.05). After treatment, compared to the control group and baseline, the SDS, SAS, tension-anxiety, depression-dejection, and confusion-bewilderment scores in the experimental group significantly decreased (P < 0.05), whereas sleep efficiency, sleep disturbance, hypnotics, and PSQI scores significantly increased (P < 0.05).

Suggestion therapy combined with escitalopram treatment can reduce the severity of depression and anxiety, change mood status, and improve sleep quality in middle-aged women with depression.

This study conducted a meta-analysis to examine the impact of exercise interventions on anxiety levels among college students.

Under Review Manager 5.3 and Stata17.0, subgroup analyses were conducted on data from 514 subjects across 10 studies from Chinese and English literature. The analyses examined intervention content, intervention period, single intervention duration and intervention frequency. A random effects model was employed to assess the overall effect size and heterogeneity.

The exercise intervention demonstrated a significant effect on reducing anxiety among college students, with a large effect size (d = -0.83). The heterogeneity test of intervention content (I2 = 0%) revealed high consistency in the specific content of exercise intervention across studies. However, substantial heterogeneity was observed in single intervention time (I2 = 75%), intervention frequency (I2 = 75%), and intervention period (I2 = 72%), indicating significant variations across studies. These differences suggest that varying durations, frequencies, and periods of intervention yielded different effects on college students' anxiety levels.

This meta-analysis has found that structured physical exercise programs, especially mind-body integrative exercises, can alleviate anxiety to the greatest extent, offering evidence-based guidance for implementing targeted exercise interventions in college mental health programs.

https://doi.org/10.37766/inplasy2024.11.0006.

An important element of supporting pharmacotherapy in hypothyroidism is a pro-health lifestyle, with rational nutrition and recreational physical activity playing important roles. Objectives: The aim of this study was to analyse selected behavioural determinants of depressive states in women with Hashimoto's disease. Methods: This study was conducted among 219 women aged 20-50 using the following: (i) the author's questionnaire of nutritional behaviours for people with hypothyroidism (QNB); (ii) the International Physical Activity Questionnaire (IPAQ); and (iii) the Beck Depression Scale (SDB). Statistical analysis was performed in Statistica 13.1 and JASP programmes, using Spearman's R correlation analysis, the Kruskal-Wallis analysis of variance and regression analysis at a significance level of α = 0.05. Results: It was found that depressive symptoms were weakly negatively associated with moderate physical activity. At the same time, women with low levels of depressive symptoms demonstrated higher levels of vigorous physical activity than women with moderate and high levels of depression. Depression symptoms decreased with the implementation of some dietary recommendations, including the consumption of products rich in iodine, iron, zinc, selenium, vitamin D, vitamin A and polyunsaturated omega-3 fatty acids. The occurrence of constipation, requiring a high-fibre diet, was positively associated with symptoms of depression. Regression analysis showed that the model consisting of all QNB items explained 18% of depression symptoms. Conclusions: In summary, among women with Hashimoto's disease, moderate physical activity and some rational dietary choices were associated with a lower intensity of depressive symptoms. Promoting a healthy lifestyle may help improve the mental state of patients with Hashimoto's disease.

Knowledge gap theory posits that individuals with better education have better opportunities to obtain, understand and utilise available information. In a health-related context, this insight could lead to a more effective disease prevention. The aim of our study was to test the hypothesis that knowledge gap underlies differences in behaviour aimed at maintaining brain health.

We conducted an online survey investigating Slovenian public view on brain, brain research, and science-based recommendations for brain health. The survey was filled out by a total of 2,568 respondents, of whom 2,450 completed it in full. They were divided into two subgroups based on their self-reported brain-related education, i.e., the lay subgroup (n = 1,012) and a topically educated group (n = 1,438), i.e., the educated subgroup. Among the latter, 728 participants reported to have a Bachelor's degree or higher education. We analysed the views of this sample subgroup on brain, neuroscience, and science-based brain health recommendations, and compared them with age- and education-matched lay subgroup (n = 565) from the same survey.

Educated individuals showed greater awareness and adherence to science-based recommendations compared to the lay respondents, specifically in the perceived importance of following a healthy diet, exercising, ensuring time for rest, relaxation and maintenance of social contacts, acquiring new knowledge and skills and using supplements that are considered to improve mental abilities (all p < 0.005), but not in the perceived importance of getting enough sleep, avoiding drugs and alcohol or injuries and performing mentally-challenging activities or cognitive training (all p > 0.10). Educated individuals more frequently reported following a healthy diet, engaging in physical activity and socialising, acquiring new knowledge and skills, performing mental challenges and cognitive training, and using supplements (all p < 0.005), but not getting sufficient sleep, avoiding drugs, alcohol or injury, or ensuring time for rest and relaxation (all p > 0.08). A larger proportion of lay than educated participants (32 and 17%, respectively) identified lack of information as a reason for not engaging in healthy practices (p < 0.001). Educated participants outperformed lay individuals in identifying diseases amenable to lifestyle modification.

Understanding the differences in brain health perceptions between educated and lay individuals is crucial for developing effective public health strategies. Our results highlight a substantial knowledge gap in the Slovenian population and the need for targeted educational interventions that account for varying degrees of knowledge in different population segments which could lead to better adherence to healthy lifestyle practices.

Wheelchair users with neuromuscular disorders have symptoms related to the disease and complications to the sedentary lifestyle, such as constipation and lower back pain. Physical training might be beneficial. This systematic review investigates the potential benefits and harms of physical training for wheelchair users with neuromuscular disorders.

We systematically searched PubMed including studies published until July 2024. Inclusion criteria: 1) participants with a neuromuscular disorder, 2) at least 60% of participants in a study were wheelchair users, 3) physical training and its effects were investigated, 4) studies were prospective, and 5) English language was used. Non-peer-reviewed articles were excluded. Search results were screened by title, abstract, and full text. Two independent authors assessed the quality with the Downs and Black Quality Index.

We included 14 studies of 140 patients from 5 types of neuromuscular disorders (Duchenne muscular atrophy, spinal muscular atrophy, limb-girdle muscular atrophy, facioscapulohumeral muscular dystrophy, and amyotrophic lateral sclerosis). The mean quality was low (16/32) due to flaws in study design, selection bias, and power. Even though many were of low quality and lacked descriptions of adverse events, they all showed positive effects. Most studies investigated physical training of mastication or respiration with improvements in both. Other findings were improvements in endurance, extremity strength, and range of motion.

Physical training of wheelchair users with neuromuscular disorders is not well investigated. Physical training seems safe and beneficial, but training of respiratory and masticatory muscles is the only well-documented exercise modality that can be advised in patients with Duchenne Muscular Dystrophy or Duchenne Muscular Dystrophy/Spinal Muscular Atrophy, respectively. Larger, high-quality trials, including other neuromuscular disorders, are needed to assess the effects and adverse events of physical training.

Persistent stressful situations can have detrimental cardiovascular effects; however, effects on the blood pressure (BP) response to exercise have not been fully examined. This study investigated the impact of a 2-wk stressful situation on the exercise pressor response. Eight healthy male university paramedic trainees underwent a 2-wk paramedic hospital training and a control period study. Pre- and postintervention, BP responses to the exercise test [2-min submaximal isometric handgrip (IHG) exercise followed by postexercise muscle ischemia (PEMI)] and cold pressure test (CPT) were assessed. A stress biomarker, salivary α-amylase (sAA) activity, significantly increased after hospital training (Pre: 8.8 ± 4.6; Post: 15.5 ± 7.3 kU/L; P = 0.036), whereas no significant changes were observed in the control period (Pre: 11.3 ± 3.6; Post: 10.4 ± 4.5 kU/L). Although no significant trial (hospital training vs. control)-by-intervention (pre- vs. post-2-wk period) interactions were detected in the mean arterial pressure (MAP) response to PEMI or CPT, a significant interaction in the MAP response to IHG exercise was noted (Δ48.9 ± 11.2 to Δ55.5 ± 9.1 mmHg, hospital training; Δ53.2 ± 14.1 to Δ51.2 ± 11.9 mmHg, control; P = 0.035). Consequently, changes in the sAA and MAP preintervention to postintervention showed a significant correlation (τ = 0.397, P = 0.036). Results showed that stressful paramedic hospital training augmented BP response to IHG exercise. This suggests that prolonged stressful situations increase pressor response to exercise, particularly in cases involving healthy young men.NEW & NOTEWORTHY Exposure to prolonged stressful situations augmented the blood pressure response to submaximal isometric exercise in healthy young men. This finding suggests that monitoring cardiovascular responses during exercise under chronic stress conditions could be important.

This study aims to investigate the mediating role of positive coping in the relationship between physical activity and psychological distress (PD) among people living with HIV/AIDS (PLWHA) in Henan, China, and to explore the moderating factor regarding this relationship. A cross-sectional study was conducted among 517 PLWHA, recruited from four cities in Henan province. Path analysis was employed to examine the mediating effect of positive coping in the link between physical activity and PD. Additionally, a moderated mediation analysis was performed to assess the moderated effect on this relationship. The indirect effect of physical activity on PD via positive coping was statistically significant (β = -0.02, SE = 0.01, 95% confidence interval (CI) [-0.04, -0.01], p < 0.05), confirming partial mediation. The total effect of physical activity on PD was significant (β = -0.10, SE = 0.03, 95% CI [-0.16, -0.04], p < 0.05). Infection duration moderated the mediation effect, with a stronger impact of positive coping on reducing PD observed in participants with an infection duration of less than 10 years (β = -0.52, SE = 0.16, p < 0.001 for <5 years; β = -0.38, SE = 0.12, p < 0.001 for 5-10 years). Physical activity plays a pivotal role in reducing PD among PLWHA by promoting positive coping mechanisms. These findings highlight the importance of incorporating physical activity interventions early in the disease progression, as this may enhance coping skills and mitigate PD.

To examine the impact of the COVID-19 pandemic on the psychological health of key stakeholders within an elite UK sports organization.

The Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) was sent electronically to 500 employees, and 8 face-to-face interviews were conducted at an elite-level professional football club.

English Premier League (EPL) Football Club.

Office/stadium staff, coaching/backroom staff, players from the male U23, women's and men's senior teams.

Stakeholder groups that were invited to participate in the study: office/stadium staff, coaching/backroom staff, players from the U23, women's and men's senior teams, and variables of age and gender.

WEMWBS scores across the office/stadium staff, coaching/backroom staff, and player cohort.

Of 122 responses (24% response rate) and 8 face-face interviews, the average WEMWBS score was 51.2 (SD ±8.4) and 14% of the cohort presented with scores suggestive of a higher risk of depression. The main findings were moderate effect size differences in WEMWBS scores with the players scoring higher than both the office/stadium staff ( P = 0.01) and the coaching/backroom staff ( P = 0.01).

Office/stadium staff experienced greater compromising mental health effects from the COVID-19 pandemic, as compared with the coaching/backroom staff and players, respectively, suggesting that elite sports organizations should also consider providing mental health education and signposting strategies for this area of the workforce.

Individual traits and habits have shown to be associated with health and health behaviour. One such habit is how individuals use music. This study aimed to examine if using music as a mood regulator is related to risk factors of lifestyle diseases. Participants who joined the present Motivation Makes the Move! lifestyle intervention were overweight and sedentary adults (n = 76, ages 19-40). They answered questionnaires about physical activity and use of music. They also underwent a cardiopulmonary exercise test and their body composition was assessed. Additionally, the analyses' robustness was tested through controlling for physical, sociodemographic and psychological health related factors. We observed that despite the participants' self-reported commitment to regular physical activity, their fitness level was poor. Using music as a mood regulator was associated with lower cardiorespiratory fitness. Use of music was also positively linked to body fat percentage, although this finding did not remain significant after adjusting for age, educational level and experienced health. We urge future research to address the relationship between music use and risk factors of lifestyle diseases in a population sample.

The molecular mechanisms involved in bone metabolism abnormalities in individuals with type 2 diabetes mellitus (T2DM) are a prominent area of investigation within the life sciences field. Myostatin (MSTN), a member of the TGF-β superfamily, serves as a critical negative regulator of skeletal muscle growth and bone metabolism. Current research on the exercise-mediated regulation of MSTN expression predominantly focuses on its role in skeletal muscle. However, due to the intricate and multifaceted mechanical and biochemical interactions between muscle and bone, the precise mechanisms by which exercise modulates MSTN to enhance bone metabolic disorders in T2DM necessitate additional exploration. The objective of this review is to systematically synthesize and evaluate the role of MSTN in the development of bone metabolism disorders associated with T2DM and elucidate the underlying mechanisms influenced by exercise interventions, aiming to offer novel insights and theoretical recommendations for enhancing bone health through physical activity.

Relevant articles in Chinese and English up to July 2024 were selected using specific search terms and databases (PubMed, CNKI, Web of Science); 147 studies were finally included after evaluation, and the reference lists were checked for other relevant research.

Myostatin's heightened expression in the bone and skeletal muscle of individuals with T2DM can impede various pathways, such as PI3K/AKT/mTOR and Wnt/β-catenin, hindering osteoblast differentiation and bone mineralization. Additionally, it can stimulate osteoclast differentiation and bone resorption capacity by facilitating Smad2-dependent NFATc1 nuclear translocation and PI3K/AKT/AP-1-mediated pro-inflammatory factor expression pathways, thereby contributing to bone metabolism disorders. Physical exercise plays a crucial role in ameliorating bone metabolism abnormalities in individuals with T2DM. Exercise can activate pathways like Wnt/GSK-3β/β-catenin, thereby suppressing myostatin and downstream Smads, CCL20/CCR6, and Nox4 target gene expression, fostering bone formation, inhibiting bone resorption, and enhancing bone metabolism in T2DM.

In the context of T2DM, MSTN has been shown to exacerbate bone metabolic disorders by inhibiting the differentiation of osteoblasts and the process of bone mineralization while simultaneously promoting the differentiation and activity of osteoclasts. Exercise interventions have demonstrated efficacy in downregulating MSTN expression, disrupting its downstream signaling pathways, and enhancing bone metabolism.

A dramatic increase in the use of videoconferencing occurred as a response to the COVID-19 pandemic, including delivery of chronic disease management programs. With this increase, clients' openness to and confidence in receiving any type of telehealth care has dramatically improved. However, the rapidity of the response was accomplished with little time to learn from existing knowledge and research.

The purpose of this scoping review was to identify features, barriers, and facilitators of synchronous videoconference interventions that actively engage clients in the management of chronic conditions.

Using scoping review methodology, MEDLINE, CINAHL, and 6 other databases were searched from 2003 onward. The included studies reported on structured, one-on-one, synchronous videoconferencing interventions that actively engaged adults in the management of their chronic conditions at home. Studies reporting assessment or routine care were excluded. Extracted text data were analyzed using thematic analysis and published taxonomies.

The 33 included articles reported on 25 distinct programs. Most programs targeted people with neurological conditions (10/25, 40%) or cancer (7/25, 28%). Analysis using the Taxonomy of Every Day Self-Management Strategies and the Behavior Change Technique Taxonomy version 1 identified common program content and behavior change strategies. However, distinct differences were evident based on whether program objectives were to improve physical activity or function (7/25, 28%) or mental health (7/25, 28%). Incorporating healthy behaviors was addressed in all programs designed to improve physical activity or function, whereas only 14% (1/7) of the programs targeting mental health covered content about healthy lifestyles. Managing emotional distress and social interaction were commonly discussed in programs with objectives of improving mental health (6/25, 24% and 4/25, 16%, respectively) but not in programs aiming at physical function (2/25, 8% and 0%, respectively). In total, 13 types of behavior change strategies were identified in the 25 programs. The top 3 types of strategies applied in programs intent on improving physical activity or function were feedback and monitoring, goals and planning, and social support, in contrast to shaping knowledge, regulation, and identity in programs with the goal of improving mental health. The findings suggest that chronic condition interventions continue to neglect evidence that exercise and strong relationships improve both physical and mental health. Videoconference interventions were seen as feasible and acceptable to clients. Challenges were mostly technology related: clients' comfort, technology literacy, access to hardware and the internet, and technical breakdowns and issues. Only 15% (5/33) of the studies explicitly described compliance with health information or privacy protection regulations.

Videoconferencing is a feasible and acceptable delivery format to engage clients in managing their conditions at home. Future program development could reduce siloed approaches by adding less used content and behavior change strategies. Addressing client privacy and technology issues should be priorities.

The joint association of dietary diversity (DD) and physical activity (PA) on anxiety, depressive symptoms, and their comorbidity have not been extensively explored. Hence, this study focused on examining this association.

Data in this cross-sectional study was derived from the Chinese Longitudinal Healthy Longevity Survey (CLHLS). Based on self-reported dietary diversity score (DDS) questions were used to assess DD, ranging from 0 to 8. DDS < 5 was defined as insufficient DD and DDS ≥ 5 was defined as sufficient DD. PA was based on a self-reported binary question. Anxiety was assessed using the Generalized Anxiety Disorder Scale-7 (GAD-7), and depressive symptoms were evaluated by the Center for Epidemiologic Studies Depression Scale-10 (CESD-10). The independent and joint associations of DD and PA on anxiety, depressive symptoms, and their comorbidity were examined by multivariable-adjusted binary logistic regression models.

In this cross-sectional study, sufficient DD was independently associated with a decreased risk of anxiety (adjusted OR = 0.57, 95% CI = 0.50-0.65), depressive symptoms (adjusted OR = 0.69, 95% CI = 0.63-0.77), and their comorbidity (adjusted OR = 0.58, 95% CI = 0.49-0.68). Similarly, exposure to current exercise was also a significant protective factor for mental health. Importantly, co-exposure to sufficient DD and current exercise may amplify the protective effects on mental health (adjusted OR = 0.47, 95% CI = 0.38-0.57 for anxiety; adjusted OR = 0.36, 95% CI = 0.31-0.42 for depressive symptoms; adjusted OR = 0.37, 95% CI = 0.29-0.48 for their comorbidity). The robustness of these associations was demonstrated in four sensitivity analyses.

Our study found that sufficient DD and current exercise were associated with a decreased risk of mental health disorders. Importantly, the combination of both appeared to enhance this protective effect. Our findings promote the joint assessment of DD and PA to provide new insights into health-related behaviors for prevention strategies for mental health disorders in older adults.

Body awareness (BA) and proprioception, which are essential components of the sense of agency (SA), are often altered in various mental disorders such as posttraumatic stress disorder (PTSD). However, the relationship between BA, proprioception, and SA, as well as the methods to manipulate them, remain unclear. This study explored using real-time gesture sonification (GS), i.e., wearable technology transforming body movements into sounds, to enhance proprioception, BA, and thus the SA.

In this within-subjects design, 17 healthy adults (mean age = 25.5 years) with varying dance expertise (novice, amateur, expert) improvised movements to match sounds with and without auditory feedback from motion sensors on wrists/ankles modulated by their gestures. BA, immersion, pleasure, and self-efficacy were measured.

Sonification significantly increased body awareness, reward, and immersion (all p < 0.05).

GS can enhance BA and the SA, pleasure, and control during physical activity. This highlights potential mental health applications, such as agency-based therapies for PTSD. Manipulating bodily perception could improve symptoms and embodiment. Further research should replicate this in clinical populations and explore neurocognitive mechanisms.

To test the effects of a physical activity intervention program on symptoms of mental disorders among adolescents.

This study is a 12-week cluster randomized controlled trial. The sample consisted of 306 adolescents (45,8% male, age: 13,6 [0,72] years; 54.2% female, age: 13.5 [0.69] years), randomized into an intervention group (N = 165) and a control group (N = 141). The physical activity program involved sessions including muscle strengthening and cardiorespiratory exercises and lifestyle guidance. The mental health indicators analyzed were: anxiety, depression, sleep, and psychological well-being. Intervention effects were analyzed by generalized estimating equations.

After 12 weeks, no significant improvements were observed in the intervention group for sleep; anxiety; depression, and psychological well-being. In the subgroup analysis, significant group×time interactions were observed for adolescents who were classified with moderate symptoms of depression (mean difference: -0.97, p = 0.002) and anxiety (mean difference: -3.03, p = 0.01) with favorable effects for intervention group.

After the 12-week intervention period, it can be concluded that 12 weeks of school-based physical activity intervention significantly reduced symptoms of anxiety and depression in adolescents with moderate/severe symptoms. Furthermore, the intervention contributed to the maintenance of psychological well-being, since the control group showed a significant reduction in this mental health indicator.

This study examined gender differences in the association between recreational walking and indoor and outdoor fall rates among older adults.

The Healthy Aging and Neighborhood Study is a prospective cohort that included 716 community-dwelling adults aged 65-95 years in central and northeastern Massachusetts, USA (2018-2023). Recreational walking at baseline was measured by the frequency of walking for exercise for at least 10 min in the participants' neighborhood. Falls were reported on monthly falls calendars, and the circumstances for reported falls were collected via subsequent telephone interviews. Mixed effects negative binomial models were used to estimate gender differences in the associations of recreational walking with rates of indoor and outdoor falls, separately. Models were adjusted for sociodemographic variables, physical health, functional status, lifestyle behaviors, mental health, and fear of falling.

There were 394 (55%) female and 322 (45%) male participants enrolled in the study, and the mean (SD) age was 74.08 (6.29). About 61% of participants engaged in recreational walking at least once weekly. Women had lower outdoor fall rates than men (32 vs. 40 per 100 person-years), while indoor fall rates did not significantly differ by gender (31 vs. 34 per 100 person-years). Women engaging in recreational walking at least once weekly had a 62% lower indoor fall rate [IRR (95% CI): 0.38 (0.21, 0.71)] than those who did not. No significant associations were observed between recreational walking and outdoor falls for both women and men.

Among community-dwelling older women, but not men, a higher frequency of recreational walking was associated with lower rates of indoor falls, while no changes were seen with outdoor falls. Increasing recreational walking may be a viable focus for fall prevention programs in the community, especially for older women.

Engaging in activity has proven to have beneficial effects on different facets of well-being, such as conditions related to the deterioration of the nervous system. Non-coding RNAs (ncRNAs) and exosomal ncRNAs associated with vesicles have been recognized as influencers of gene expression and cell signaling, potentially contributing to the positive impact of physical activity on neurodegenerative conditions. It is hypothesized that exercise-induced changes in ncRNA expression may regulate key processes involved in neuroprotection, including neuroinflammation, oxidative stress, protein aggregation, and synaptic function. Exercise has shown promise in preventing neurodegenerative diseases (NDs), and ncRNAs and exosomal ncRNAs are emerging as potential mediators of these benefits. In review, we explored how ncRNAs and exosomal ncRNAs play a role in enhancing the impacts of activity on neurodegenerative disorders for future treatments. Research studies, both preclinical and clinical, that have documented the use of various exercises and their effects on ncRNAs and exosomal ncRNAs for the treatment of NDs have been compiled and enlisted from the PubMed database, spanning the time period from the year 2000 up to the current time. Studies show that manipulating specific ncRNAs or harnessing exercise-induced changes in ncRNA expression and exosomal cargo could potentially be utilized as therapeutic strategies for preventing or treating NDs. In conclusion, studies suggest that various exercise modalities, including aerobic, resistance, and high-intensity interval training, can modulate the expression of ncRNAs and exosomal ncRNAs in the context of NDs. The altered ncRNA profiles may contribute to the neuroprotective and therapeutic effects observed with exercise interventions. However, more research is needed to fully understand the underlying mechanisms and to further explore the potential of exercise-induced ncRNA signatures as biomarkers and therapeutic targets for neurodegenerative disorders.

Limited guidance exists for conducting research on health disparities within the field of sport and exercise medicine (SEM). This review aimed to identify and summarise existing best practices for conducting equitable, diverse and inclusive research within SEM.

A narrative review with evidence synthesis was conducted using electronic databases, reference lists, manual searches and relevant publications from other organisations. Search terms associated with steps of the research process were used in tandem with 'equity', 'inclusion' and 'health disparities'.

We developed a research roadmap for SEM researchers with methodological recommendations to develop and conduct equity-informed and equity-focused research. This roadmap serves as a tool for SEM researchers and clinicians to design, execute and disseminate research with a health disparities lens. We recommend SEM researchers should build an equitable, diverse and inclusive research team and include community members; apply a multilevel, intersectional framework; minimise and acknowledge potential biases in the study design and incorporate qualitative or mixed-methods approaches if appropriate; apply multiple inclusive strategies for recruiting and retaining diverse populations; collect accurate and representative data using inclusive data collection methods and tools with validity and reliability in the populations of interest; apply measures with evidence of validity and reliability in the populations of interest; implement a data analysis plan that reflects the conceptual and theoretical frameworks; and promote broad dissemination and interventions that ultimately address and reduce health inequities.

SEM researchers should consider these methodological recommendations to conduct equity-informed and equity-focused research to address health disparities in SEM.

This research examines the link between physical activity (PA) and adolescent psychological sub-health (PSH), emphasizing the intermediary roles of self-control (SC) and mobile phone addiction (MPA). Utilizing the Physical Activity Rating Scale (PARS), SC Scale (SCS), MPA Tendency Scale (MPATS), and the Multidimensional Subhealth Questionnaire of Adolescents (MSQA), data were gathered from 1,052 adolescents. The findings indicate that (1) PA is negatively associated with both PSH and MPA, yet positively correlates with SC. Additionally, SC is inversely linked to PSH and MPA, whereas MPA is directly associated with PSH. (2) The analysis shows that SC and MPA partially mediate the impact of PA on PSH. (3) Moreover, both factors act as sequential mediators in the relationship between PA and PSH. These results enhance our understanding of the pathways through which physical activity influences adolescent PSH and offer important theoretical and practical perspectives for employing PA to boost adolescent mental health.

The COVID-19 pandemic has led to a global health crisis and a significant increase in psychological distress and psychopathological symptoms. We conducted a randomized controlled trial with two online interventions derived from positive psychology (PP) and acceptance and commitment therapy (ACT) in N = 138 "homestayers" during the first lock-down period in Germany. PP exercises had a positive impact on anxiety scores, which decreased significantly during the intervention, particularly in participants without access to a garden. Direct or indirect social contact, movement/exercise, and exposure to nature were the most frequently reported helpful coping strategies. We conclude that low-threshold online interventions with a focus on positive aspects of people's lives may be helpful to support mental health during pandemic crises. From a mental health perspective, the results also reinforce the approach of countries that allow their citizens to, for example, still go for walks during periods of contact restrictions, compared to full lock-down conditions.

The aim of this study was to conduct a network meta-analysis to assess the effectiveness of various forms of exercise as an intervention for post-cancer depression and to provide a guiding program based on evidence-based medicine for subsequent clinical practice.

This review was registered on the PROSPERO website with ID CRD42023485407. Pubmed, Embase, Cochrane Library, and Web of Science were comprehensively searched to obtain published articles from the establishment of the database until October 7, 2023. Bayesian network meta-analysis was conducted. Statistical analysis was conducted using R4.3.2 and Stata 15.1.

This study ultimately included 51 articles and 4956 samples. Aerobic exercise (SMD = -0.33, 95%CI: 0.58, -0.08), combined exercise (SMD = -0.48, 95%CI: 0.71, -0.26), and mind-body exercise (SMD = -0.35, 95%CI: 0.6, -0.09) significantly improved depression compared with usual care (UC). According to the SUCRA value and cumulative probability, the rank of depression improvement effect of various sports interventions is as follows: combined exercise (90.71%), mind-body exercise (69.64%), aerobic exercise (65.81%), resistance training (35.86%).

Exercise intervention can significantly improve post-cancer depression, but there is no significant difference in the effectiveness of various forms of exercise in improving post-cancer depression.

Occupational drivers are exposed to a wide range of risk factors, including sedentary behavior and physical inactivity, which can contribute to various chronic diseases. However, exercise interventions are likely to alleviate the negative associations and reduce chronic disease risks. This systematic review aimed to inventorize research studies investigating the effects of physical activity and exercise interventions on health outcomes in occupational drivers, and to assess interventions that have demonstrated effectiveness on health outcomes in occupational drivers.

The electronic databases "Web of Science," "Scopus," and "PubMed" were searched using keywords related to "occupational drivers," "exercise," and "health outcomes." Studies were included if they examined the effects of physical activity and exercise among occupational drivers on the following health outcomes: pain, disability, lifestyle factors (sleep, weight, physical activity, nutrition), fatigue, stress, and cardiometabolic risk factors. The methodological quality of the studies was assessed by the Cochrane Risk of Bias tools for randomized and non-randomized studies.

Fourteen articles were included (three randomized and 11 non-randomized controlled trials). All studies were judged to have an overall risk of bias as "some concerns, low, moderate or serious." Evidence suggests that stretching and isometric exercises have significantly improved pain, disability, and fatigue. In contrast, multicomponent lifestyle interventions have enhanced physical activity levels, cardiometabolic risk factors, anthropometrics (body mass index, weight, waist circumference), sleep, and dietary intake among occupational drivers.

The available evidence indicates the potential benefits of exercise interventions and physical activity for health outcomes in occupational drivers. However, high-quality studies are needed in the future to establish stronger evidence supporting the effect of the exercise intervention.

This study investigated the association between gait speed, handgrip strength, and their combination, and the risk for developing clinically relevant depressive symptoms in community-dwelling older adults.

A secondary analysis was conducted using data from the ASPirin in Reducing Events in the Elderly study. Participants were community-dwelling older adults in Australia and the United States of America followed for a median (interquartile range) of 3.97 (2.26) years. Baseline handgrip strength and gait speed were used as exposure variables, and their combination categories were also explored. Depression was measured using the modified Center for Epidemiological Studies Depression 10-item scale (CES-D 10). Cox regression was used to estimate Adjusted Hazard Ratios (AHR) with 95 % Confidence Intervals (CI) after adjusting for a range of potential confounders.

A total of 17,231 participants (55.3 % women) were included in the analysis. Slow gait and weak grip at baseline were associated with the risk of depression (AHR: 1.20; CI: 1.11-1.29 and 1.14; 1.06-1.23, respectively). The combination of the two physical performance measures was associated with a 31 % increase in the risk of depression (1.31; 1.16-1.47) and a significant dose-response association was observed for quintiles of gait and grip with depression.

Although the CES-D 10 is a validated scale, it is a self-reported tool rather than a clinical diagnosis of depression.

Low physical function may be a risk factor for depression in older adults. This highlights the inextricable link between the physical and mental health of older adults, which can inform potential clinical and public health prevention strategies for depression in later life.