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For: Badawy AAB, Dawood S, Bano S. Kynurenine pathway of tryptophan metabolism in pathophysiology and therapy of major depressive disorder. World J Psychiatry 2023; 13(4): 141-148 [PMID: 37123095 DOI: 10.5498/wjp.v13.i4.141]
URL: https://www.wjgnet.com/2220-3206/full/v13/i4/141.htm
Number Citing Articles
1
Wen Li, Lili Yang, Haozhi Chen, Jia Miao, Yutong Wang, Changlin Zhou, Yanqi Chen, Ziyang Kong, Chengyue Shen, Jiafei Wu, Jinyi Li, Luoying Zhu, Zhengjun Li, Yaoyao Bian. Depression, stress, and tryptophan metabolism through the kynurenine pathway: treatment strategies from the perspective of Chinese herbal medicineMetabolic Brain Disease 2024; 40(1) doi: 10.1007/s11011-024-01461-1
2
Huiying Zhao, Wei Wu. Nutritional Interventions for Perimenopausal Anxiety and Depression Targeting Tryptophan and GABA Pathways: A Narrative ReviewNutrients 2026; 18(13) doi: 10.3390/nu18132185
3
Wei Guo, Jing-Zheng Zhang, Lu-Yuan Cui, Kai-Ming Wang, Juan Zhang, Cheng-Shi Jiang. Current applications and development of dual-target inhibitors of Ido1/TDO: From tumor immunology to neuropsychiatric disordersEuropean Journal of Medicinal Chemistry 2026; 314 doi: 10.1016/j.ejmech.2026.118946
4
Yingying Pan, Peiwei Xu, Xueli Sun, Rosemary Bassey. Associations between Kynurenine pathway metabolites and cognitive dysfunction in major depressive disorderPLOS One 2025; 20(8) doi: 10.1371/journal.pone.0328886
5
Sudeepa Bhattacharyya, Siamak MahmoudianDehkordi, Matthew J. Sniatynski, Marina Belenky, Vasant R. Marur, A. John Rush, W. Edward Craighead, Helen S. Mayberg, Boadie W. Dunlop, Bruce S. Kristal, Rima Kaddurah-Daouk. Metabolomics signatures of serotonin reuptake inhibitor (escitalopram), serotonin norepinephrine reuptake inhibitor (duloxetine) and cognitive-behavioral therapy on key neurotransmitter pathways in major depressive disorderJournal of Affective Disorders 2025; 375 doi: 10.1016/j.jad.2025.01.064
6
Hadi Nasiri, Zahra Valedkarimi, Morteza Akbari. Gut–brain–immune axis implications for mental health and diseaseMolecular and Cellular Biochemistry 2025; 480(10) doi: 10.1007/s11010-025-05325-9
7
Yuxin Lin, Luyao Wang, Sining Meng, Jianjia Liu, Xinyu Li, Wenjuan Wang, Miaoyang Hu, Xi Wang, Weixia Duan, Shangcheng Xu, Jun Wang, Rong Gao. 3-hydroxykynurenine increase in kynurenine pathway driven bisphenol F induced anxiety- and depression-like behaviorsScience of The Total Environment 2025; 995 doi: 10.1016/j.scitotenv.2025.180073
8
Maryna Tsvetkova , Nataliia Korzh, Pavlo Petrushanko. Psychoneuroimmunological mechanisms of stress-induced mental and psychosomatic disordersMedical Science of Ukraine (MSU) 2026; 22(2) doi: 10.32345/2664-4738.2.2026.20
9
Nisang Chen, Xiaoting Wu, Mingqi Tu, Sangsang Xiong, Junyan Jin, Siying Qu, Shuangyi Pei, Jianqiao Fang, Xiaomei Shao. Optimizing Treatment for Major Depressive Disorder in Adolescents: The Impact of Intradermal Acupuncture - A Randomized Controlled Trial ProtocolNeuropsychiatric Disease and Treatment 2023;  doi: 10.2147/NDT.S420489
10
Trevor W. Stone, L. Gail Darlington, Abdulla A.-B. Badawy, Richard O. Williams. The Complex World of Kynurenic Acid: Reflections on Biological Issues and Therapeutic StrategyInternational Journal of Molecular Sciences 2024; 25(16) doi: 10.3390/ijms25169040
11
Dian He, Si-Yi Guo, Yi-Chun Yang, Hai-Yang Wang, Yi Zhang, Xiao-Long Mo, Lan-Xiang Liu, Zheng-Hong Qin, Peng Xie. NADPH alleviates LPS-induced neuropathology and depression-like behaviors by suppressing microglial inflammatory responseTranslational Psychiatry 2025; 16(1) doi: 10.1038/s41398-025-03761-1
12
Yaoyao Sun, Yundan Liao, Yuyanan Zhang, Zhe Lu, Yuzhuo Ma, Zhewei Kang, Xiaoyang Feng, Guorui Zhao, Junyuan Sun, Yunqing Zhu, Rui Yuan, Yang Yang, Liangkun Guo, Xiao Zhang, Dai Zhang, Runsen Chen, Wenjian Bi, Weihua Yue. Genome-wide interaction association analysis identifies interactive effects of childhood maltreatment and kynurenine pathway on depressionNature Communications 2025; 16(1) doi: 10.1038/s41467-025-57066-4
13
Junbiao Zhan, Yuxi Zhang, Hao Tian, Xizi Zhu, Manlin Guo, Zhen Qiu, Zhongyuan Xia. Mechanism of antidepressant action of ketamine and differences between its two enantiomersJournal of Anesthesia and Translational Medicine 2025; 4(3) doi: 10.1016/j.jatmed.2025.06.001
14
Qi Zhang, Yu-hui Tang, Xiao-Qing Tang. Physiology of the kynurenine pathway and its implications in CNS disordersReviews in the Neurosciences 2026; 37(4) doi: 10.1515/revneuro-2025-0130
15
Yiqing Zhou, Jiajia Fan, Li Cao, Xuan Li, Yao Dong, Shuguang Fang, Ying Wu, Shaobin Gu. A food-borne probiotic ameliorates depression by modulating tryptophan metabolism along the gut-brain axisBrain, Behavior, and Immunity 2026; 137 doi: 10.1016/j.bbi.2026.106866
16
Meishan Liu. Pathogenesis and therapeutic strategies for cancer-related depressionAmerican Journal of Cancer Research 2024; 14(9) doi: 10.62347/WVVG5364
17
Zekun Liu, Daole Wei, Siyuan An, Wenjing Cui, Julhash U. Kazi, Honglu Diao, Mingpeng Zhao, Peng-Chao Wang, Zhenshan Yang. Tryptophan metabolism in embryo implantation and decidualizationTissue and Cell 2026; 101 doi: 10.1016/j.tice.2026.103522
18
Zhihan Ye, Shuran Yang, Liu Lu, Ming Zong, Lieying Fan, Chuanyuan Kang. Unlocking the potential of the 3-hydroxykynurenine/kynurenic acid ratio: a promising biomarker in adolescent major depressive disorderEuropean Archives of Psychiatry and Clinical Neuroscience 2025; 275(4) doi: 10.1007/s00406-024-01815-x
19
Naghmeh Nikkheslat, Zuzanna Zajkowska, Cristina Legido-Quigley, Jin Xu, Pedro H. Manfro, Laila Souza, Rivka Pereira, Fernanda Rohrsetzer, Jader Piccin, Anna Viduani, Brandon A. Kohrt, Helen L. Fisher, Christian Kieling, Valeria Mondelli. Sex-Specific Alterations of the Kynurenine Pathway in Association With Risk for and Remission of Depression in AdolescenceBiological Psychiatry 2025; 98(7) doi: 10.1016/j.biopsych.2024.11.020
20
Guanwen Zhu, Jiawen Liu, Sijia Wang, Long Wang. Systemic inflammation and mental health: A J-shaped dose-response pattern in depression based on NHANES 2005 to 2018Medicine 2026; 105(27) doi: 10.1097/MD.0000000000049348
21
Abdulla A-B Badawy. Kynurenine pathway and suicidal ideation in treatment-resistant depressionJournal of Psychopharmacology 2023; 37(11) doi: 10.1177/02698811231196584
22
Yun-Tian Xie, Yu-Jing Yang. Research fronts and researchers of <i>World Journal of Psychiatry</i> in 2023: A visualization and analysis of mapping knowledge domainsWorld Journal of Psychiatry 2024; 14(7): 1118-1126 doi: 10.5498/wjp.v14.i7.1118
23
Justyna Jasionowska, Piotr Gałecki, Ewa Kalinka, Aleksandra Skiba, Janusz Szemraj, Elżbieta Turska, Monika Talarowska. Level of selected exponents of the kynurenine pathway in patients diagnosed with depression and selected cancersJournal of Psychiatric Research 2024; 179 doi: 10.1016/j.jpsychires.2024.09.008
24
Ao Yan, Zhejin Li, Yuanwei Gao, Fanglong Hu, Shuo Han, Fengjie Liu, Zhongcheng Liu, Jinting Chen, Chunmao Yuan, Chengyan Zhou. Isobicyclogermacrenal ameliorates hippocampal ferroptosis involvement in neurochemical disruptions and neuroinflammation induced by sleep deprivation in ratsPhytomedicine 2025; 136 doi: 10.1016/j.phymed.2024.156306
25
Hui Liu, Lina Hu, Yalan Wang, Zheshan Quan, Zheng Liu, Shiben Wang, Qingkun Shen. Design, Synthesis, and Biological Evaluation of Novel Morpholine–Coumarin Derivatives for Inflammation-Associated DepressionBiomolecules 2026; 16(7) doi: 10.3390/biom16071002
26
Lingzhuo Kong, Huaizhi Wang, Ruiqi Sang, Saboor Saeed, Yuting Shen, Jianbo Lai, Shaohua Hu. Down-regulated expressions of LOC151174, GSTT1, and IFI27L1 in the peripheral blood exhibit the biological and immunological features of major depressive disorderJournal of Affective Disorders 2026; 394 doi: 10.1016/j.jad.2025.120687
27
Kirolos Eskandar. The gut–brain axis in depression, anxiety, and schizophrenia: a scoping review of mechanisms, biomarkers, and therapeutic implicationsMiddle East Current Psychiatry 2025; 32(1) doi: 10.1186/s43045-025-00585-z
28
Kiuanne Lino Lobo Metzker, Khiany Mathias, Richard Simon Machado, Sandra Bonfante, Larissa Joaquim, Marina Goulart da Silva, Guilherme Cabreira Daros, Elisa Mitkus Flores Lins, Fernanda Belle, Carolina Giassi Alano, Rafaela Tezza Matiola, Isabela da Silva Lemos, Lucinéia Gainski Danielski, Fernanda Frederico Gava, Rafael Mariano de Bitencourt, Franciane Bobinski, Emilio Luiz Streck, Gislaine Zilli Reus, Fabricia Petronilho. Amelioration of Neurochemical Alteration and Memory and Depressive Behavior in Sepsis by Allopurinol, a Tryptophan 2,3-Dioxygenase InhibitorCNS & Neurological Disorders - Drug Targets 2024; 23(12) doi: 10.2174/0118715273282363240415045927
29
Raed M. Al-Zoubi, Mai Elaarag, Ahmad R. Al-Qudimat, Enas A. Al-Hurani, Zainab E. Fares, Ala’a Farhan, Sally R. Al-Zoubi, Abbas Khan, Abdelali Agouni, Mohanad Shkoor, Hiba Bawadi, Zain Z. Zakaria, Mazhar Al Zoubi, Khalid Alrumaihi. IDO and TDO inhibitors in cancer immunotherapy: mechanisms, clinical development, and future directionsFrontiers in Pharmacology 2025; 16 doi: 10.3389/fphar.2025.1632446
30
Shan Huang, Yanping Bai, Xingwu Duan. The Kynurenine Pathway in Psoriasis: Mechanisms and Therapeutic OpportunitiesInflammation 2025; 48(6) doi: 10.1007/s10753-025-02339-9
31
Francesco Bavato, Andrea Steuer, Anna M. Jacobsen, Amelie Zacher, Josua Zimmermann, David M. Cole, Antje Opitz, Markus R. Baumgartner, Ann-Kathrin Stock, Christian Beste, Boris B. Quednow. Differential alterations in peripheral tryptophan pathways in methamphetamine versus MDMA users are linked to their contrasting psychiatric symptomsTranslational Psychiatry 2026; 16(1) doi: 10.1038/s41398-026-04069-4
32
Muntajin Rahman, Khadija Akter, Amama Rani, Moon Nyeo Park, Bonglee Kim. Herbal Neurotherapeutics for Cognitive Disorders: Integrative Mechanisms Linking Neurotransmitter Systems, Neurodegeneration, and the Gut-Brain AxisNutrients 2026; 18(11) doi: 10.3390/nu18111796
33
Samina Bano, Humaira Sharif, Faiza Sajid, Sumaiya Binte Hamid, Abdulla A-B Badawy. Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour – studies with chronic nicotine administration in ratsBehavioural Pharmacology 2023; 34(6) doi: 10.1097/FBP.0000000000000736
34
Valerio Dell’Oste, Lionella Palego, Andrea Bordacchini, Berenice Rimoldi, Livia Parrini, Virginia Pedrinelli, Gino Giannaccini, Laura Betti, Claudia Carmassi. Comparing plasma levels and ratios of tryptophan, serotonin, kynurenine and quinolinic acid between patients with bipolar disorder and healthy controls: impact of depressive episode or post-traumatic stress disorder symptomsFrontiers in Psychiatry 2026; 16 doi: 10.3389/fpsyt.2025.1680907
35
Dominika Ładno, Beata Nowak, Aleksandra Palka, Dominik Strzelecki, Oliwia Gawlik-Kotelnicka. Selected Lipidome Components and Their Association with Perinatal DepressionNutrients 2025; 17(22) doi: 10.3390/nu17223590
36
Reiji YOSHIMURA, Chihiro WATANABE. Comorbidity of Major Depression and Type 2 Diabetes Mellitus: Epidemiology, Pathophysiology, and Treatment ApproachesJournal of UOEH 2025; 47(2) doi: 10.7888/juoeh.47.95