Anti-aging based on stem cell therapy: A scoping review

Figure 1 Telomeres on the end of chromosomes are believed to protect the DNA strands and prevent them from fusing with other strands. Telomeres lose a little of their length during each cell division. Since replicative DNA polymerases are not able to replicate telomeres, and telomerase is not expressed in normal mammalian somatic cells, telomeres become too short to replicate after a fixed number of cell divisions. Eventually, the cell will stop growing and enter cellular senescence.