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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Exp Med. Jun 20, 2026; 16(2): 115894
Published online Jun 20, 2026. doi: 10.5493/wjem.v16.i2.115894
Letter to the Editor: Urinary infection in European guidelines 2025 vs microbiology culture results in the management of urinary infection
Mohamed Wishahi, Mohamed Badawy
Mohamed Wishahi, Mohamed Badawy, Department of Urology, Theodor Bilharz Research Institute, Cairo 12411, Egypt
Author contributions: Wishahi M and Badawy M designed the research study; performed the research; contributed to analyzing the data, wrote the manuscript; and all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Mohamed Wishahi, MD, PhD, Full Professor, Department of Urology, Theodor Bilharz Research Institute, Embaba, Giza, Cairo 12411, Egypt. moh.weshahy@gmail.com
Received: October 29, 2025
Revised: November 11, 2025
Accepted: January 21, 2026
Published online: June 20, 2026
Processing time: 228 Days and 7.9 Hours
Core Tip

Core Tip: The European Association of Urology guidelines 2025 for urinary infections (UIs) published new classification describing localized and systemic UIs. Patient’s Symptoms, clinical examinations, laboratory, and imaging investigation are required to set up the diagnosis. Localized UIs could be treated on an ambulatory basis, while systemic infection indicates hospitalization and monitoring. Urine culture would not reveal all bacterial community in urine. Second generation sequencing reveals bacterial community including dysbiosis and helper microbiota. Implementing the new guidelines would lead to personalized medicine, minimizing antibiotics use, avoid antibiotic resistance, and considering probiotics in treatment of localized infections.

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