Basic Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Exp Med. Mar 20, 2025; 15(1): 94022
Published online Mar 20, 2025. doi: 10.5493/wjem.v15.i1.94022
SARS-CoV-2 proteins show great binding affinity to resin composite monomers and polymerized chains
Pedro Henrique Sette-de-Souza, Moan Jéfter Fernandes Costa, Boniek Castillo Dutra Borges
Pedro Henrique Sette-de-Souza, Moan Jéfter Fernandes Costa, Faculdade de Odontologia, Universidade de Pernambuco-campus Arcoverde, Arcoverde 56503-146, Pernambuco, Brazil
Pedro Henrique Sette-de-Souza, Programa de Pós-Graduação em Saúde e Desenvolvimento Socioambiental, Universidade de Pernambuco-campus Garanhuns, Garanhuns 55294-902, Pernambuco, Brazil
Moan Jéfter Fernandes Costa, Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada, Universidade de Pernambuco-campus Santo Amaro, Recife 50100-130, Pernambuco, Brazil
Boniek Castillo Dutra Borges, Department of Odontologia, Universidade Federal do Rio Grande do Norte, Natal 59056-000, Rio Grande do Norte, Brazil
Boniek Castillo Dutra Borges, Programa de Pós-Graduação em Ciências Odontológicas, Universidade Federal do Rio Grande do Norte, Natal 59056-000, Rio Grande do Norte, Brazil
Author contributions: Sette-de-Souza PH, Fernandes Costa MJ and Dutra Borges BC designed, performed the experiments, acquired, analyzed, and interpreted the data; all of the authors wrote the manuscript and approved the final version of the article.
Supported by The Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES), No. 001.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Data sharing statement: Request to the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Pedro Henrique Sette-de-Souza, DDS, MSc, PhD, Full Professor, Faculdade de Odontologia, Universidade de Pernambuco-campus Arcoverde, Rua Cícero Monteiro de Melo, s/n-São Cristóvão, Arcoverde/PE, Arcoverde 56503-146, Pernambuco, Brazil. pedro.souza@upe.br
Received: March 10, 2024
Revised: October 3, 2024
Accepted: October 30, 2024
Published online: March 20, 2025
Processing time: 291 Days and 7.6 Hours
Core Tip

Core Tip: The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) may interact with monomers of resin composites; triethylene glycol dimethacrylate has the smallest affinity with SARS-CoV-2 among monomers; bisphenol-A glycol dimethacrylate and bisphenol-A ethoxylated dimethacrylate show a remarkable affinity mainly with papain-like protease.