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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Exp Med. Mar 20, 2025; 15(1): 100402
Published online Mar 20, 2025. doi: 10.5493/wjem.v15.i1.100402
Published online Mar 20, 2025. doi: 10.5493/wjem.v15.i1.100402
Alcohol and alcoholism associated neurological disorders: Current updates in a global perspective and recent recommendations
Prashanti Sahu, Department of Zoology, GGU Bilaspur, Bilaspur 495009, Chhattīsgarh, India
Henu Kumar Verma, Department of Lung Health and Immunity, Helmholtz Zentrum Munich, Munich 85764, Bayren, Germany
LVKS Bhaskar, Department of Zoology, Guru Ghasidas Vishwavidyalaya, Bilaspur 495001, Chhattīsgarh, India
Author contributions: Sahu P and Verma HK performed the literature search, collected and assembled the data, and analyzed the obtained articles; Verma HK and Bhaskar L designed the review; Bhaskar L supervised the complete article; Sahu P, Verma HK, and Bhaskar L wrote the manuscript and revised the manuscript critically; all authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: LVKS Bhaskar, DSc, PhD, Professor, Department of Zoology, Guru Ghasidas Vishwavidyalaya, Koni Bilaspur, Bilaspur 495001, Chhattīsgarh, India.
Received: August 16, 2024
Revised: November 27, 2024
Accepted: December 16, 2024
Published online: March 20, 2025
Processing time: 132 Days and 19.6 Hours
Revised: November 27, 2024
Accepted: December 16, 2024
Published online: March 20, 2025
Processing time: 132 Days and 19.6 Hours
Core Tip
Core Tip: This review delves into the neurobiology of alcohol use disorder (AUD), highlighting the role of neurotransmitter imbalances, genetic factors like alcohol dehydrogenase 1B gene and aldehyde dehydrogenase 2 gene, and the associated neurological disorders. It explores the complex mechanisms underlying neuronal degeneration and blood brain barrier dysfunction in AUD, offering insights for future research into the acute and chronic neurological effects of alcoholism.