Garg G, Bharadwaj A, Chaudhary S, Gupta V. Chemical profiling of bioactive compounds in the methanolic extract of wild leaf and callus of Vitex negundo using gas chromatography-mass spectrometry. World J Exp Med 2024; 14(1): 88064 [PMID: 38590309 DOI: 10.5493/wjem.v14.i1.88064]
Corresponding Author of This Article
Alok Bharadwaj, PhD, Associate Professor, Biotechnology, GLA University, 17 Km Mile Stone, Mathura-Delhi Highway NH#1, Post-Chaumuhan District, Mathura 281406, Uttar Pradesh, India. alok.bhardwaj@gla.ac.in
Research Domain of This Article
Biochemical Research Methods
Article-Type of This Article
Clinical and Translational Research
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Exp Med. Mar 20, 2024; 14(1): 88064 Published online Mar 20, 2024. doi: 10.5493/wjem.v14.i1.88064
Chemical profiling of bioactive compounds in the methanolic extract of wild leaf and callus of Vitex negundo using gas chromatography-mass spectrometry
Gunjan Garg, Shweta Chaudhary, School of Biotechnology, Gautam Buddha University, Greater Noida 201312, Uttar Pradesh, India
Alok Bharadwaj, Biotechnology, GLA University, Mathura 281406, Uttar Pradesh, India
Veena Gupta, Division of Germplasm Conservation, Indian Council of Agricultural Research - National Bureau of Plant Genetic Resources, New Delhi 110012, New Delhi, India
Author contributions: Garg G and Chaudhary S contributed to the conceptualization of this study, writing the original draft, reviewing, and editing; Bharadwaj A was involved in the data collection, analysis and interpretation of results; Gupta V participated in critical revision of the article, and editing.
Institutional review board statement: This study did not involve animal or human experimentation. Thus, an institutional review board statement is not required.
Clinical trial registration statement: This study did not involve animal or human experimentation. Thus, a clinical trial registration statement is not required.
Informed consent statement: This study did not involve animal or human experimentation. Thus, an informed consent statement is not required.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data to those presented in the study are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Alok Bharadwaj, PhD, Associate Professor, Biotechnology, GLA University, 17 Km Mile Stone, Mathura-Delhi Highway NH#1, Post-Chaumuhan District, Mathura 281406, Uttar Pradesh, India. alok.bhardwaj@gla.ac.in
Received: September 8, 2023 Peer-review started: September 8, 2023 First decision: October 24, 2023 Revised: November 12, 2023 Accepted: January 30, 2024 Article in press: January 30, 2024 Published online: March 20, 2024 Processing time: 193 Days and 5 Hours
Core Tip
Core Tip: Phytopharmacological analysis of medicinal plants and their extracts can show the presence of important elements and gives insight into new methods for drug therapy. Vitex negundo (L.) is a perennial herb belonging to the Varbanaceae family, an aromatic small tree widely used in conventional medicine. In the present study, we report the gas chromatography-mass spectrometry analysis of leaf extracts from wild plants and correlate the existence of these components with those present in callus extracts. The medicinal application of Vitex negundo for various diseases has been recognized due to the identification of various bioactive compounds, and the plant is recognized as an important botanical remedy in medical research and development.
