Short-term blood pressure variability as an indicator of the adaptive capacity of patients with chronic heart failure

doi:10.5493/wjem.v15.i4.110904

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Dec 20, 2025 (publication date) through Dec 19, 2025

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Exp Med. Dec 20, 2025; 15(4): 110904
Published online Dec 20, 2025. doi: 10.5493/wjem.v15.i4.110904

Table 1 The main clinical characteristics in the groups of examined patients, n (%)/median (25^th-75^th percentiles)/mean ± SD

Indicator	Main group (n = 46)	Comparison group (n = 28)	Significance of differences, (P value)
Age (years)	60 (56.0,64.0)	60.0 (55.0,65.0)	0.975
Male	30 (65.22)	18 (64.29)	0.934
Female	16 (34.78)	10 (35.71)	0.769
Height (cm)	166.8 ± 7.7	167.1 ± 6.6	0.885
Body weight (kg)	86.2 (74.3-94.2)	82.7 (70.2-90.3)	0.921
BMI (kg/m²)	32.07 (25.64-35.14)	29.13 (28.12-30.22)	0.806
FC CHF			0.309
II FC	16 (34.7)	12 (42.9)
III FC	30 (55.3)	16 (57.1)
DECG parameters
LVEDD (cm)	5.08 (4.7-5.2)	5.2 (4.8-5.3)	0.578
LVESD	3.22 (2.9-3.6)	3.13 (3.1-3.6)	0.888
LAESD	3.7 (3.5-4.1)	3.7 (3.6-4.1)	0.527
LVEF (%)	64.0 (58.0-66.0)	61.0 (59.0-67.0)	0.737
LVMMI (g/m²)	108.0 (99.0-128.0)	105.0 (94.0-150.0)	0.283
SPAP (mmHg)	28.0 (25.0-36.0)	27.0 (24.0-27.0)	0.052
TAPSE (cm)	2.12 (2.0-2.22)	2.1 (2.0-2.2)	0.599
6MWT parameters
Distance covered, test 1 (meters)	362.0 (310.0-440.0)	394.0 (375.0-451.0)	0.328
Distance covered, test 2 (meters)	390.0 (307.0-471.0)	416.0 (395.0-487.0)	0.205
THRR, test 1 (second)	94.0 (41.0-197.0)	62.5 (45.0-68.0)	0.403
Adaptation index	1.05 (1.02-1.1)	1.07 (1.03-1.1)	0.317
SBP initial (before starting 6MWT) (mmHg)	127.9 (117-139)	129.6 (109,136)	0.783
SBP1 (immediately after 6MWT) (mmHg)	137.6 (116-151)	140.1 (123-154)	0.728
SBP2 (20 minutes after 6MWT) (mmHg)	120.2 (110-129)	120.9 (108-126)	0.896
SBPV1-2 6MWT (mmHg)	36.0 (25.0-41.0)	32.0 (26.0-43.0)	0.709

BMI: Body mass index; FC CHF: Functional class of chronic heart failure; DECG: Doppler echocardiography; LVEDD: Left ventricular end-diastolic dimension; LVESD: Left ventricular end-systolic dimension; LAESD: Left atrium end-systolic dimension; LVEF: Left ventricular ejection fraction; LVMMI: Left ventricular myocardial mass index; SPAP: Systolic pulmonary arterial pressure; TAPSE: Tricuspid annular plane systolic excursion; 6MWT: 6-minute walk test; THRR: Time of heart rate recovery; SBP: Systolic blood pressure; SBPV1-2 6MWT: Systolic blood pressure variability during 6-minute walk test.

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Citation: Akimova NS, Konshina LE, Runnova AE, Zhuravlev MO, Bogdanova TM, Kiselev AR, Shvarts YG. Short-term blood pressure variability as an indicator of the adaptive capacity of patients with chronic heart failure. World J Exp Med 2025; 15(4): 110904
URL: https://www.wjgnet.com/2220-315X/full/v15/i4/110904.htm
DOI: https://dx.doi.org/10.5493/wjem.v15.i4.110904