Pinocembrin as a novel anti-cancer agent: Exploring preclinical evidence along with therapeutic potential
Neelam Singla, Piyush Mittal, M Arockia Babu, Soumya V Menon, Subhashree Ray, Haider Ali, Manish Purohit, Kavita Goyal, Rakhi Mishra, Md Sadique Hussain, Arcot Rekha, Gaurav Gupta
Neelam Singla, Manish Purohit, School of Pharmacy, Suresh Gyan Vihar University, Jaipur 302017, Rajasthan, India
Piyush Mittal, School of Pharmacy, Sharda University, Greater Noida 201306, India
M Arockia Babu, Institute of Pharmaceutical Research, GLA University, Mathura 281406, Uttar Pradesh, India
Soumya V Menon, Department of Chemistry and Biochemistry, Jain (Deemed to be University), Bengaluru 560041, Karnataka, India
Subhashree Ray, Department of Nephrology IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhuban 751003, Odisha, India
Haider Ali, Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, Tamil Nadu, India
Manish Purohit, Department of Pharmacy, Govt Polytechnic Malab, Nuh 122107, Haryana, India
Kavita Goyal, Department of Biotechnology, Graphic Era (Deemed to be University), Dehra Dun 248002, Uttarakhand, India
Rakhi Mishra, Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida 201306, India
Md Sadique Hussain, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehra Dun 248007, Uttarakhand, India
Arcot Rekha, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune 411018, Maharashtra, India
Gaurav Gupta, Centre for Research Impact and Outcome-Chitkara College of Pharmacy, Chitkara University, Rajpura 433221, Punjab, India
Gaurav Gupta, Centre of Medical and Bio-allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates
Author contributions: Singla N, Mittal P, and Babu MA were responsible for formal analysis, data curation; V Menon S, Ray S, and Ali H were responsible for methodology and investigation; Purohit M, Goyal K, Mishra R, and Hussain MS were responsible for resources and project administration; Rekha A and Gupta G were responsible for validation, software, writing original draft, and visualization; all authors have read and approved the final version of the file.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Gaurav Gupta, PhD, Professor, Research Dean, Centre for Research Impact and Outcome-Chitkara College of Pharmacy, Chitkara University, Chitkara, Rajpura 433221, Punjab, India.
gauravpharma25@gmail.com
Received: June 10, 2025
Revised: July 2, 2025
Accepted: October 9, 2025
Published online: December 20, 2025
Processing time: 195 Days and 17 Hours
