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©The Author(s) 2024.
World J Crit Care Med. Mar 9, 2024; 13(1): 88540
Published online Mar 9, 2024. doi: 10.5492/wjccm.v13.i1.88540
Published online Mar 9, 2024. doi: 10.5492/wjccm.v13.i1.88540
Characteristic | All patients (n =218) | Blood culture results | P value | |
Negative or contamination (n = 133) | Positive with pathogen (n = 85) | |||
Age (yr) | 63 (53–73) | 64 (53–73) | 62 (52–70) | 0.253 |
Sex (male/female) | 218 (122/96) | 133 (81/52) | 85 (41/44) | 0.066 |
Comorbidities | ||||
Hypertension | 79 (36.2) | 50 (37.6) | 29 (34.1) | 0.603 |
Diabetes | 49 (22.5) | 29 (21.8) | 20 (23.5) | 0.766 |
Cardiovascular disease | 23 (10.6) | 17 (12.8) | 6 (7.1) | 0.18 |
COPD | 16 (7.3) | 13 (9.8) | 3 (3.5) | 0.085 |
Cerebrovascular disease | 34 (15.6) | 26 (19.5) | 8 (9.4) | 0.044 |
Primary diagnosis for cultures | ||||
Respiratory | 101 (46.3) | 81 (60.9) | 20 (23.5) | < 0.001 |
Intestinal | 50 (22.9) | 28 (21.1) | 22 (25.9) | 0.408 |
Urogenital | 33 (15.1) | 12 (9.0) | 21 (24.7) | 0.002 |
Hepatobiliary | 21 (9.6) | 6 (4.5) | 15 (17.6) | 0.001 |
Skin/soft tissue | 5 (2.3) | 3 (2.3) | 2 (2.4) | 1.0 |
Other | 8 (3.7) | 3 (2.3) | 5 (5.9) | 0.308 |
APACHE II | 20 (14-25) | 19 (14-25) | 20 (14-27) | 0.533 |
Mechanical ventilation (yes/no) | 218 (156/62) | 133 (100/33) | 85 (56/29) | 0.137 |
Renal replacement (yes/no) | 218 (29/189) | 133 (13/120) | 85 (16/69) | 0.055 |
28-d mortality | 81 (37.2) | 46 (34.6) | 35 (41.2) | 0.326 |
Characteristic | All patients (n = 218) | Blood culture results | P value | |
Negative or contamination (n = 133) | Positive with pathogen (n = 85) | |||
PCT (ng/mL) | 6.9 (1.1-32.1) | 2.85 (0.4-16.6) | 16.8 (4.1-112.3) | < 0.001 |
CRP (mg/mL) | 113.3 (47.9-174.3) | 99.4 (41.1-168.3) | 128.1 (68.5-189.7) | 0.047 |
WBC (× 109/L) | 12.3 (8.1–17.8) | 11.7 (8.8–16.8) | 13.1 (7.5–21.7) | 0.404 |
Neutrophils (%) | 90.1 (82.5-93.5) | 88.9 (83.4-92.3) | 92.2 (82.3-94.7) | 0.029 |
Haemoglobin (g/L) | 109.6 ± 23.8 | 109.9 ± 24 | 109.2 ± 23.6 | 0.824 |
HBA1C | 5.9 (5.4-7.2) | 6.0 (5.6-7.1) | 5.8 (5.3-8.6) | 0.7 |
PT (s) | 14.4 (12.7-16.7) | 13.9 (12.7-15.7) | 15.5 (12.7-17.5) | 0.012 |
APTT (s) | 34.5 (30.2-41.5) | 33.3 (29.6-38.0) | 37.2 (30.2-44.8) | 0.005 |
Fib (g/L) | 3.94 (3.0-4.97) | 3.95 (3.19-5.26) | 3.93 (2.85-4.87) | 0.344 |
D-dimer (μg/mL) | 6.37 (2.62-12.34) | 5.33 (2.19-10.94) | 8.06 (3.93-13.81) | 0.02 |
Alanine aminotransferase (U/L) | 31.8 (18–61.2) | 24.2 (14.8–47.5) | 43.4 (23.1–113.9) | < 0.001 |
Aspartate aminotransferase (U/L) | 46.2 (29.6–87.1) | 37.9 (25.8–70) | 67.2 (35.2–170.4) | < 0.001 |
Total bilirubin (μmol/L) | 15.6 (9.1–29.1) | 13.5 (8.9–23.7) | 20.6 (10.7–49) | 0.009 |
Serum albumin (g/L) | 28.8 (24.4-31.7) | 28 (24.2-32.2) | 29.4 (25-31.5) | 0.444 |
BUN (mmol/L) | 9.9 (6.0–15.3) | 9.2 (5.9–14.2) | 10.8 (6.2–15.9) | 0.147 |
Cr (μmol/L) | 99.6 (67.3–180) | 89.1 (62.4–146) | 134.5 (84.7–221) | 0.001 |
Microorganism | No. (%) isolated from blood cultures |
Gram-positive bacteria | 24 (28.2) |
Staphylococcus aureus | 6 (7.1) |
Staphylococcus epidermidis | 3 (3.5) |
Staphylococcus haemolyticus | 2 (2.4) |
Staphylococcus hominis | 2 (2.4) |
Staphylococcus caprae | 1 (1.2) |
Enterococcus faecium | 5 (5.9) |
Streptococcus pyogenes | 3 (3.5) |
Streptococcus viridans | 1 (1.2) |
Enterococcus gallinarum | 1 (1.2) |
Gram-negative bacteria | 59 (69.4) |
Escherichia coli | 36 (42.3) |
Klebsiella pneumoniae | 15 (17.6) |
Pseudomonas aeruginosa | 3 (3.5) |
Aeromonas sobria | 2 (2.4) |
Enterobacter cloacae | 1 (1.2) |
Klebsiella oxytoca | 1 (1.2) |
Acinetobacter lwoffii | 1 (1.2) |
Fungus | 2 (2.4) |
Candida albicans | 2 (2.4) |
- Citation: Li X, Wang S, Ma J, Bai SG, Fu SZ. Predictive value of thrombocytopenia for bloodstream infection in patients with sepsis and septic shock. World J Crit Care Med 2024; 13(1): 88540
- URL: https://www.wjgnet.com/2220-3141/full/v13/i1/88540.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v13.i1.88540