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©The Author(s) 2023.
World J Crit Care Med. Jun 9, 2023; 12(3): 139-152
Published online Jun 9, 2023. doi: 10.5492/wjccm.v12.i3.139
Published online Jun 9, 2023. doi: 10.5492/wjccm.v12.i3.139
Figure 1 Electron transport chain through mitocondrial complexes and oxidative phosphorylation.
ADP: Adenosine diphosphtate; ATP: Adenosine triphosphate; Cyt c: Cytochrome c; GSH: Gluthatione synthetase; NAD: Nicotinamide adenine dinucleotide; NADH: Nicotinamide adenine dinucleotide (reduced); SOD: Superoxide dismuthase.
Figure 2 Mitochondrial DNA damage as a potential trigger for the inflammatory response.
DAMP: Damage associated molecular patterns; mtDNA: Mitochondrial deoxyribonucleic acid; PAMP: Pathogen associated molecular patterns; ROS: Reactive oxygen species.
Figure 3 Example of a respirometry assay.
ATP: Adenosine triphosphate.
- Citation: Nedel W, Deutschendorf C, Portela LVC. Sepsis-induced mitochondrial dysfunction: A narrative review. World J Crit Care Med 2023; 12(3): 139-152
- URL: https://www.wjgnet.com/2220-3141/full/v12/i3/139.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v12.i3.139