©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Feb 4, 2016; 5(1): 96-102
Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.96
Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.96
Mild to moderate intra-abdominal hypertension: Does it matter?
Liivi Maddison, Joel Starkopf, Annika Reintam Blaser, Department of Anaesthesiology and Intensive Care, University of Tartu, 51014 Tartu, Estonia
Liivi Maddison, Joel Starkopf, Department of Anaesthesiology and Intensive Care, Tartu University Hospital, 51014 Tartu, Estonia
Annika Reintam Blaser, Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Lucerne Cantonal Hospital, 6000 Lucerne, Switzerland
Author contributions: All authors contributed to the concept of the manuscript; Maddison L drafted the manuscript; Starkopf J and Reintam Blaser A made critical revisions related to important intellectual content of the manuscript; all authors approved the final version of the manuscript.
Supported by the Ministry of Education and Research of Estonia (IUT34-24).
Conflict-of-interest statement: The authors have no conflict of interest to declare.
Correspondence to: Annika Reintam Blaser, MD, PhD, Department of Anaesthesiology and Intensive Care, University of Tartu, Puusepa 8, 51014 Tartu, Estonia. annika.reintam.blaser@ut.ee
Telephone: +37-25-142281 Fax: +37-25-142281
Received: August 29, 2015
Peer-review started: September 6, 2015
First decision: October 27, 2015
Revised: November 18, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: February 4, 2016
Processing time: 147 Days and 11 Hours
Peer-review started: September 6, 2015
First decision: October 27, 2015
Revised: November 18, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: February 4, 2016
Processing time: 147 Days and 11 Hours
Core Tip
Core tip: This review summarizes the epidemiology, pathophysiological consequences and impact on outcome of mild to moderate intra-abdominal hypertension (IAH) and focuses on tasks for future research in the field. More than half of IAH patients present with IAH Grade I and approximately a quarter with IAH grade II. Even mild IAH can have a negative impact on tissue perfusion and be associated with impaired clinical outcomes. However, the impact of IAH and its different grades on mortality is controversial. Clear triggers for interventions in different patient groups with mild to moderate IAH are not defined.