©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Crit Care Med. Mar 9, 2026; 15(1): 114998
Published online Mar 9, 2026. doi: 10.5492/wjccm.v15.i1.114998
Published online Mar 9, 2026. doi: 10.5492/wjccm.v15.i1.114998
Revisiting acute kidney injury outcomes in traumatic brain injury
Nupur Karan, Department of Anaesthesiology, All India Institute of Medical Sciences, Raipur 492099, Chhattisgarh, India
Rohit Patnaik, Department of Critical Care Medicine, Medeor 24x7 Hospital, Abu Dhabi 40330, United Arab Emirates
Author contributions: Karan N wrote the original draft; Karan N and Patnaik R contributed to the conceptualization, writing, reviewing, and editing, participated in drafting the manuscript; all authors have read and approved the final version of the manuscript.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Corresponding author: Rohit Patnaik, DM, Department of Critical Care Medicine, Medeor 24x7 Hospital, Al Falah Street – Al Danah – Zone 1, Abu Dhabi 40330, United Arab Emirates.
Received: October 9, 2025
Revised: November 21, 2025
Accepted: January 9, 2026
Published online: March 9, 2026
Processing time: 143 Days and 17.5 Hours
Revised: November 21, 2025
Accepted: January 9, 2026
Published online: March 9, 2026
Processing time: 143 Days and 17.5 Hours
Core Tip
Core Tip: Trauma-related acute kidney injury is a critical concern in traumatic brain injury care, affecting up to 10% of intensive care unit patients. Since creatinine is a late marker, early prediction is vital. Strategies must focus on preventing hyperchloremia using novel biomarkers (e.g., neutrophil gelatinase-associated lipocalin/kidney injury molecule 1) and risk stratification tools to detect subclinical injury and prevent collateral kidney damage.