Published online Jun 9, 2026. doi: 10.5492/wjccm.v15.i2.114619
Revised: November 11, 2025
Accepted: February 2, 2026
Published online: June 9, 2026
Processing time: 239 Days and 14.3 Hours
Urolithiasis is one of the most prevalent condition with evolving management strategies. While extracorporeal shock wave lithotripsy (ESWL) and ureteroscopic lithotripsy (URSL) are common minimally invasive treatments, their comparative efficacy, safety, and impact on quality of life (QoL) require continuous evaluation.
To compare the clinical efficacy, safety, patient satisfaction, and economic outcomes of ESWL vs URSL in the management of lower ureteric stones.
This randomized controlled trial included 240 adult patients with confirmed lower ureteric calculi, allocated equally to ESWL or URSL groups. Baseline characteristics, stone parameters, procedural details, complications, and follow-up outcomes - including stone clearance, pain, QoL, workdays lost, cost, and satisfaction - were systematically analyzed over a 3-month follow-up.
URSL demonstrated significantly higher stone-free rates at all time points (e.g., 95% at 3 months) compared to ESWL (55.83%). While ESWL was associated with fewer complications, it required more sessions and resulted in lower immediate postoperative QoL and higher workdays lost. Conversely, ESWL was more cost-effective and highly satisfactory, with better early pain scores. Stone size and density influenced success, favoring URSL for larger or denser stones. Overall, both modalities are effective, but treatment choice should be individualized based on stone characteristics and patient factors.
URSL offers superior stone clearance, particularly for larger stones, with acceptable safety profiles. ESWL remains a viable non-invasive option for smaller stones, providing better QoL recovery and economic benefits. Individualized treatment planning is essential for optimal outcomes.
Core Tip: Management of acute colic due to lower ureteric calculi requires balancing stone clearance, patient comfort, and treatment costs. Ureteroscopic lithotripsy achieves higher stone-free rates and patient satisfaction, especially in larger or complex stones, whereas extracorporeal shock wave lithotripsy remains a less invasive, cost-effective option suitable for smaller stones. Treatment should therefore be individualized, considering stone characteristics, patient preferences, and resource availability.