1
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Wang DD, Lin S, Lyu GR. Advances in the Application of Artificial Intelligence in the Ultrasound Diagnosis of Vulnerable Carotid Atherosclerotic Plaque. ULTRASOUND IN MEDICINE & BIOLOGY 2025; 51:607-614. [PMID: 39828500 DOI: 10.1016/j.ultrasmedbio.2024.12.010] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 09/23/2024] [Revised: 12/16/2024] [Accepted: 12/17/2024] [Indexed: 01/22/2025]
Abstract
Vulnerable atherosclerotic plaque is a type of plaque that poses a significant risk of high mortality in patients with cardiovascular disease. Ultrasound has long been used for carotid atherosclerosis screening and plaque assessment due to its safety, low cost and non-invasive nature. However, conventional ultrasound techniques have limitations such as subjectivity, operator dependence, and low inter-observer agreement, leading to inconsistent and possibly inaccurate diagnoses. In recent years, a promising approach to address these limitations has emerged through the integration of artificial intelligence (AI) into ultrasound imaging. It was found that by training AI algorithms with large data sets of ultrasound images, the technology can learn to recognize specific characteristics and patterns associated with vulnerable plaques. This allows for a more objective and consistent assessment, leading to improved diagnostic accuracy. This article reviews the application of AI in the field of diagnostic ultrasound, with a particular focus on carotid vulnerable plaques, and discusses the limitations and prospects of AI-assisted ultrasound. This review also provides a deeper understanding of the role of AI in diagnostic ultrasound and promotes more research in the field.
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Affiliation(s)
- Dan-Dan Wang
- Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China
| | - Shu Lin
- Centre of Neurological and Metabolic Research, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China; Group of Neuroendocrinology, Garvan Institute of Medical Research, Sydney, Australia
| | - Guo-Rong Lyu
- Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China; Departments of Medical Imaging, Quanzhou Medical College, Quanzhou, China.
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2
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Chevalier O, Dubey G, Benkabbou A, Majbar MA, Souadka A. Comprehensive overview of artificial intelligence in surgery: a systematic review and perspectives. Pflugers Arch 2025; 477:617-626. [PMID: 40087157 DOI: 10.1007/s00424-025-03076-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/05/2024] [Revised: 03/06/2025] [Accepted: 03/07/2025] [Indexed: 03/17/2025]
Abstract
The rapid integration of artificial intelligence (AI) into surgical practice necessitates a comprehensive evaluation of its applications, challenges, and physiological impact. This systematic review synthesizes current AI applications in surgery, with a particular focus on machine learning (ML) and its role in optimizing preoperative planning, intraoperative decision-making, and postoperative patient management. Using PRISMA guidelines and PICO criteria, we analyzed key studies addressing AI's contributions to surgical precision, outcome prediction, and real-time physiological monitoring. While AI has demonstrated significant promise-from enhancing diagnostics to improving intraoperative safety-many surgeons remain skeptical due to concerns over algorithmic unpredictability, surgeon autonomy, and ethical transparency. This review explores AI's physiological integration into surgery, discussing its role in real-time hemodynamic assessments, AI-guided tissue characterization, and intraoperative physiological modeling. Ethical concerns, including algorithmic opacity and liability in high-stakes scenarios, are critically examined alongside AI's potential to augment surgical expertise. We conclude that longitudinal validation, improved AI explainability, and adaptive regulatory frameworks are essential to ensure safe, effective, and ethically sound integration of AI into surgical decision-making. Future research should focus on bridging AI-driven analytics with real-time physiological feedback to refine precision surgery and patient safety strategies.
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Affiliation(s)
- Olivia Chevalier
- Institut-Mines Telecom Business School, Université Paris 1 Panthéon-Sorbonne, Paris, France
| | - Gérard Dubey
- Institut-Mines Telecom Business School, Université Paris 1 Panthéon-Sorbonne, Paris, France
| | - Amine Benkabbou
- Surgical Oncology Department, National Institute of Oncology, Mohammed V University, Rabat, Morocco
| | - Mohammed Anass Majbar
- Surgical Oncology Department, National Institute of Oncology, Mohammed V University, Rabat, Morocco
| | - Amine Souadka
- Surgical Oncology Department, National Institute of Oncology, Mohammed V University, Rabat, Morocco.
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3
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Stefanis C, Manisalidis I, Stavropoulou E, Stavropoulos A, Tsigalou C, Voidarou C(C, Constantinidis TC, Bezirtzoglou E. Assessing the Impact of Aviation Emissions on Air Quality at a Regional Greek Airport Using Machine Learning. TOXICS 2025; 13:217. [PMID: 40137544 PMCID: PMC11945904 DOI: 10.3390/toxics13030217] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/18/2025] [Revised: 03/04/2025] [Accepted: 03/14/2025] [Indexed: 03/29/2025]
Abstract
Aviation emissions significantly impact air quality, contributing to environmental degradation and public health risks. This study aims to assess the impact of aviation-related emissions on air quality at Alexandroupolis Regional Airport, Greece, and evaluate the role of meteorological factors in pollution dispersion. Using machine learning models, we analyzed emissions data, including CO2, NOx, CO, HC, SOx, PM2.5, fuel consumption, and meteorological parameters from 2019-2020. Results indicate that NOx and CO2 emissions showed the highest correlation with air traffic volume and fuel consumption (R = 0.63 and 0.67, respectively). Bayesian Linear Regression and Linear Regression emerged as the most accurate models, achieving an R2 value of 0.96 and 0.97, respectively, for predicting PM2.5 concentrations. Meteorological factors had a moderate influence, with precipitation negatively correlated with PM2.5 (-0.03), while temperature and wind speed showed limited effects on emissions. A significant decline in aviation emissions was observed in 2020, with CO2 emissions decreasing by 28.1%, NOx by 26.5%, and PM2.5 by 35.4% compared to 2019, reflecting the impact of COVID-19 travel restrictions. Carbon dioxide had the most extensive percentage distribution, accounting for 75.5% of total emissions, followed by fuels, which accounted for 24%, and the remaining pollutants, such as NOx, CO, HC, SOx, and PM2.5, had more minor impacts. These findings highlight the need for optimized air quality management at regional airports, integrating machine learning for predictive monitoring and supporting policy interventions to mitigate aviation-related pollution.
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Affiliation(s)
- Christos Stefanis
- Laboratory of Hygiene and Environmental Protection, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece; (I.M.); (E.S.); (C.T.); (T.C.C.); (E.B.)
| | - Ioannis Manisalidis
- Laboratory of Hygiene and Environmental Protection, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece; (I.M.); (E.S.); (C.T.); (T.C.C.); (E.B.)
- Delphis S.A., 14564 Kifisia, Greece
| | - Elisavet Stavropoulou
- Laboratory of Hygiene and Environmental Protection, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece; (I.M.); (E.S.); (C.T.); (T.C.C.); (E.B.)
| | | | - Christina Tsigalou
- Laboratory of Hygiene and Environmental Protection, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece; (I.M.); (E.S.); (C.T.); (T.C.C.); (E.B.)
| | | | - Theodoros C. Constantinidis
- Laboratory of Hygiene and Environmental Protection, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece; (I.M.); (E.S.); (C.T.); (T.C.C.); (E.B.)
| | - Eugenia Bezirtzoglou
- Laboratory of Hygiene and Environmental Protection, Faculty of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece; (I.M.); (E.S.); (C.T.); (T.C.C.); (E.B.)
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4
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Lo Bianco G, Robinson CL, D’Angelo FP, Cascella M, Natoli S, Sinagra E, Mercadante S, Drago F. Effectiveness of Generative Artificial Intelligence-Driven Responses to Patient Concerns in Long-Term Opioid Therapy: Cross-Model Assessment. Biomedicines 2025; 13:636. [PMID: 40149612 PMCID: PMC11940240 DOI: 10.3390/biomedicines13030636] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/14/2025] [Revised: 02/28/2025] [Accepted: 03/04/2025] [Indexed: 03/29/2025] Open
Abstract
Background: While long-term opioid therapy is a widely utilized strategy for managing chronic pain, many patients have understandable questions and concerns regarding its safety, efficacy, and potential for dependency and addiction. Providing clear, accurate, and reliable information is essential for fostering patient understanding and acceptance. Generative artificial intelligence (AI) applications offer interesting avenues for delivering patient education in healthcare. This study evaluates the reliability, accuracy, and comprehensibility of ChatGPT's responses to common patient inquiries about opioid long-term therapy. Methods: An expert panel selected thirteen frequently asked questions regarding long-term opioid therapy based on the authors' clinical experience in managing chronic pain patients and a targeted review of patient education materials. Questions were prioritized based on prevalence in patient consultations, relevance to treatment decision-making, and the complexity of information typically required to address them comprehensively. We assessed comprehensibility by implementing the multimodal generative AI Copilot (Microsoft 365 Copilot Chat). Spanning three domains-pre-therapy, during therapy, and post-therapy-each question was submitted to GPT-4.0 with the prompt "If you were a physician, how would you answer a patient asking…". Ten pain physicians and two non-healthcare professionals independently assessed the responses using a Likert scale to rate reliability (1-6 points), accuracy (1-3 points), and comprehensibility (1-3 points). Results: Overall, ChatGPT's responses demonstrated high reliability (5.2 ± 0.6) and good comprehensibility (2.8 ± 0.2), with most answers meeting or exceeding predefined thresholds. Accuracy was moderate (2.7 ± 0.3), with lower performance on more technical topics like opioid tolerance and dependency management. Conclusions: While AI applications exhibit significant potential as a supplementary tool for patient education on opioid long-term therapy, limitations in addressing highly technical or context-specific queries underscore the need for ongoing refinement and domain-specific training. Integrating AI systems into clinical practice should involve collaboration between healthcare professionals and AI developers to ensure safe, personalized, and up-to-date patient education in chronic pain management.
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Affiliation(s)
- Giuliano Lo Bianco
- Anesthesiology and Pain Department, Foundation G. Giglio Cefalù, 90015 Palermo, Italy
| | - Christopher L. Robinson
- Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Harvard University, Boston, MA 02115, USA;
| | - Francesco Paolo D’Angelo
- Department of Anaesthesia, Intensive Care and Emergency, University Hospital Policlinico Paolo Giaccone, 90127 Palermo, Italy;
| | - Marco Cascella
- Anesthesia and Pain Medicine, Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, 84081 Baronissi, Italy;
| | - Silvia Natoli
- Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy;
- Pain Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
| | - Emanuele Sinagra
- Gastroenterology and Endoscopy Unit, Fondazione Istituto San Raffaele Giglio, 90015 Cefalù, Italy;
| | - Sebastiano Mercadante
- Main Regional Center for Pain Relief and Supportive/Palliative Care, La Maddalena Cancer Center, Via San Lorenzo 312, 90146 Palermo, Italy;
| | - Filippo Drago
- Department of Biomedical and Biotechnological Sciences, University of Catania, 95124 Catania, Italy;
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5
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Antel R, Whitelaw S, Gore G, Ingelmo P. Moving towards the use of artificial intelligence in pain management. Eur J Pain 2025; 29:e4748. [PMID: 39523657 PMCID: PMC11755729 DOI: 10.1002/ejp.4748] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/10/2024] [Revised: 09/15/2024] [Accepted: 10/14/2024] [Indexed: 11/16/2024]
Abstract
BACKGROUND AND OBJECTIVE While the development of artificial intelligence (AI) technologies in medicine has been significant, their application to acute and chronic pain management has not been well characterized. This systematic review aims to provide an overview of the current state of AI in acute and chronic pain management. DATABASES AND DATA TREATMENT This review was registered with PROSPERO (ID# CRD42022307017), the international registry for systematic reviews. The search strategy was prepared by a librarian and run in four electronic databases (Embase, Medline, Central, and Web of Science). Collected articles were screened by two reviewers. Included studies described the use of AI for acute and chronic pain management. RESULTS From the 17,601 records identified in the initial search, 197 were included in this review. Identified applications of AI were described for treatment planning as well as treatment delivery. Described uses include prediction of pain, forecasting of individualized responses to treatment, treatment regimen tailoring, image-guidance for procedural interventions and self-management tools. Multiple domains of AI were used including machine learning, computer vision, fuzzy logic, natural language processing and expert systems. CONCLUSION There is growing literature regarding applications of AI for pain management, and their clinical use holds potential for improving patient outcomes. However, multiple barriers to their clinical integration remain including lack validation of such applications in diverse patient populations, missing infrastructure to support these tools and limited provider understanding of AI. SIGNIFICANCE This review characterizes current applications of AI for pain management and discusses barriers to their clinical integration. Our findings support continuing efforts directed towards establishing comprehensive systems that integrate AI throughout the patient care continuum.
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Affiliation(s)
- Ryan Antel
- Department of AnesthesiaMcGill UniversityMontrealQuebecCanada
- Faculty of Medicine and Health SciencesMcGill UniversityMontrealQuebecCanada
| | - Sera Whitelaw
- Faculty of Medicine and Health SciencesMcGill UniversityMontrealQuebecCanada
| | - Genevieve Gore
- Schulich Library of Physical Sciences, Life Sciences, and EngineeringMcGill UniversityMontrealQuebecCanada
| | - Pablo Ingelmo
- Department of AnesthesiaMcGill UniversityMontrealQuebecCanada
- Edwards Family Interdisciplinary Center for Complex Pain, Montreal Children's HospitalMcGill University Health CenterMontrealQuebecCanada
- Alan Edwards Center for Research in PainMontrealQuebecCanada
- Research InstituteMcGill University Health CenterMontrealQuebecCanada
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6
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Zhan Y, Hao Y, Wang X, Guo D. Advances of artificial intelligence in clinical application and scientific research of neuro-oncology: Current knowledge and future perspectives. Crit Rev Oncol Hematol 2025; 209:104682. [PMID: 40032186 DOI: 10.1016/j.critrevonc.2025.104682] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/01/2024] [Revised: 02/16/2025] [Accepted: 02/25/2025] [Indexed: 03/05/2025] Open
Abstract
Brain tumors refer to the abnormal growths that occur within the brain's tissue, comprising both primary neoplasms and metastatic lesions. Timely detection, precise staging, suitable treatment, and standardized management are of significant clinical importance for extending the survival rates of brain tumor patients. Artificial intelligence (AI), a discipline within computer science, is leveraging its robust capacity for information identification and combination to revolutionize traditional paradigms of oncology care, offering substantial potential for precision medicine. This article provides an overview of the current applications of AI in brain tumors, encompassing the primary AI technologies, their working mechanisms and working workflow, the contributions of AI to brain tumor diagnosis and treatment, as well as the role of AI in brain tumor scientific research, particularly in drug innovation and revealing tumor microenvironment. Finally, the paper addresses the existing challenges, potential solutions, and the future application prospects. This review aims to enhance our understanding of the application of AI in brain tumors and provide valuable insights for forthcoming clinical applications and scientific inquiries.
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Affiliation(s)
- Yankun Zhan
- First People's Hospital of Linping District; Linping Campus, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311100, China
| | - Yanying Hao
- First People's Hospital of Linping District; Linping Campus, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311100, China
| | - Xiang Wang
- First People's Hospital of Linping District; Linping Campus, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311100, China.
| | - Duancheng Guo
- Cancer Institute, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
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7
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Joe YE, Ha N, Lee W, Byon HJ. Prediction of Postoperative Pain and Side Effects of Patient-Controlled Analgesia in Pediatric Orthopedic Patients Using Machine Learning: A Retrospective Study. J Clin Med 2025; 14:1459. [PMID: 40094919 PMCID: PMC11899821 DOI: 10.3390/jcm14051459] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/27/2024] [Revised: 02/06/2025] [Accepted: 02/12/2025] [Indexed: 03/19/2025] Open
Abstract
Background/Objectives: Appropriate postoperative management, especially in pediatric patients, can be challenging for anesthesiologists. This retrospective study used machine learning to investigate the effects and complications of patient-controlled analgesia (PCA) in children undergoing orthopedic surgery. Methods: The medical records of children who underwent orthopedic surgery in a single tertiary hospital and received intravenous and epidural PCA were analyzed. Predictive models were developed using machine learning, and various demographic, anesthetic, and surgical factors were investigated to predict postoperative pain and complications associated with PCA. Results: Data from 1968 children were analyzed. Extreme gradient boosting effectively predicted moderate postoperative pain for the 6-24-h (area under curve (AUC): 0.85, accuracy (ACC): 0.79) and 24-48-h (AUC: 0.89, ACC: 0.87) periods after surgery. The factors that predicted moderate postoperative pain included the pain score immediately before the measurement period, the total amount of opioid infused, and age. For predicting side effects during the 6-24-h period after surgery, a least absolute shrinkage and selection operator model (AUC: 0.75, ACC: 0.64) was selected, while a random forest model (AUC: 0.91, ACC: 0.87) was chosen for the 24-48-h period post-surgery. The factors that predicted complications included the occurrence of side effects immediately before the measurement period, the total amount of opioid infused before the measurement period, and age. Conclusions: This retrospective study introduces machine-learning-based models and factors aimed at forecasting moderate postoperative pain and complications of PCA in children undergoing orthopedic surgery. This research has the potential to enhance postoperative pain management strategies for children.
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Affiliation(s)
- Young-Eun Joe
- Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea
| | - Nayoung Ha
- Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul 08826, Republic of Korea
| | - Woojoo Lee
- Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul 08826, Republic of Korea
| | - Hyo-Jin Byon
- Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
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Saxena S, Barreto Chang OL, Suppan M, Meco BC, Vacas S, Radtke F, Matot I, Devos A, Maze M, Gisselbaek M, Berger-Estilita J. A comparison of large language model-generated and published perioperative neurocognitive disorder recommendations: a cross-sectional web-based analysis. Br J Anaesth 2025:S0007-0912(25)00006-6. [PMID: 39922789 DOI: 10.1016/j.bja.2025.01.001] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/15/2024] [Revised: 01/02/2025] [Accepted: 01/02/2025] [Indexed: 02/10/2025] Open
Abstract
BACKGROUND Perioperative neurocognitive disorders (PNDs) are common complications after surgery and anaesthesia, particularly in older adults, leading to increased morbidity, mortality, and healthcare costs. Therefore, major medical societies have developed recommendations for the prevention and treatment of PNDs. Our study evaluated the reliability of large language models, specifically ChatGPT-4 and Gemini, in generating recommendations for PND management and comparing them with published guidelines. METHODS We conducted an online cross-sectional web-based analysis over 48 h in June 2024. Artificial intelligence (AI)-generated recommendations were produced in six different locations across five countries (Switzerland, Belgium, Turkey, Canada, and the East and West Coasts of the USA). The English prompt 'a table of a bundle of care for perioperative neurocognitive disorders' was entered into ChatGPT-4 and Gemini, generating tables evaluated by independent reviewers. The primary outcomes were the Total Disagreement Score (TDS) and Quality Assessment of Medical Artificial Intelligence (QAMAI), which compared AI-generated recommendations with published guidelines. RESULTS The study generated 14 tables, with TDS and QAMAI scores showing similar results for ChatGPT-4 and Gemini (2 [1-3] vs 2 [2-3], P=0.636 and 4 [4-4] vs 4 [3-4], P=0.424, respectively). AI-generated recommendations aligned well with published guidelines, with the highest alignment observed in ChatGPT-4-generated recommendations. No complete agreement with guidelines was achieved, and lack of cited sources was a noted limitation. CONCLUSIONS Large language models can generate perioperative neurocognitive disorder recommendations that align closely with published guidelines. However, further validation and integration of clinician feedback are required before clinical application.
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Affiliation(s)
- Sarah Saxena
- Department of Surgery, Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium; Department of Anesthesiology, Helora, Mons, Belgium
| | - Odmara L Barreto Chang
- Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, USA. https://twitter.com/@OdmaraBarreto
| | - Melanie Suppan
- Division of Anesthesiology, Department of Anesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
| | - Basak Ceyda Meco
- Department of Anaesthesia and Intensive Care, Ankara University Faculty of Medicine, Ankara, Turkey; Ankara University Brain Research Center (BAUM), Ankara, Turkey
| | - Susana Vacas
- Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
| | - Finn Radtke
- Department of Anaesthesia and Intensive Care, Hospital of Nykøbing Falster, University of Southern Denmark, Odense, Denmark
| | - Idit Matot
- Division of Anesthesia, Intensive Care, and Pain Management, Tel-Aviv Medical Center, Tel-Aviv University, Tel-Aviv, Israel
| | - Arnout Devos
- ETH AI Center, Swiss Federal Institute of Technology Zurich (ETH Zurich), Zurich, Switzerland
| | - Mervyn Maze
- Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, USA
| | - Mia Gisselbaek
- Division of Anesthesiology, Department of Anesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; Unit of Development and Research in Medical Education (UDREM), Faculty of Medicine, University of Geneva, Geneva, Switzerland
| | - Joana Berger-Estilita
- Institute for Medical Education, University of Bern, Bern, Switzerland; CINTESIS@RISE, Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal.
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9
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Kong AYH, Liu N, Tan HS, Sia ATH, Sng BL. Artificial intelligence in obstetric anaesthesiology - the future of patient care? Int J Obstet Anesth 2025; 61:104288. [PMID: 39577145 DOI: 10.1016/j.ijoa.2024.104288] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/07/2023] [Revised: 08/28/2024] [Accepted: 10/13/2024] [Indexed: 11/24/2024]
Abstract
The use of artificial intelligence (AI) in obstetric anaesthesiology shows great potential in enhancing our practice and delivery of care. In this narrative review, we summarise the current applications of AI in four key areas of obstetric anaesthesiology (perioperative care, neuraxial procedures, labour analgesia and obstetric critical care), where AI has been employed to varying degrees for decision support, event prediction, risk stratification and procedural assistance. We also identify gaps in current practice and propose areas for further research. While promising, AI cannot replace the expertise and clinical judgement of a trained obstetric anaesthesiologist. It should, instead, be viewed as a valuable tool to facilitate and support our practice.
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Affiliation(s)
- A Y H Kong
- Department of Women's Anaesthesia, KK Women's and Children's Hospital, Singapore.
| | - N Liu
- Centre for Quantitative Medicine and Programme in Health Services and Systems Research, Duke-NUS Medical School, Singapore
| | - H S Tan
- Department of Women's Anaesthesia, KK Women's and Children's Hospital, Singapore; Anaesthesiology and Perioperative Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore
| | - A T H Sia
- Department of Women's Anaesthesia, KK Women's and Children's Hospital, Singapore; Anaesthesiology and Perioperative Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore
| | - B L Sng
- Department of Women's Anaesthesia, KK Women's and Children's Hospital, Singapore; Anaesthesiology and Perioperative Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore
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10
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Nie S, Zhang S, Zhao Y, Li X, Xu H, Wang Y, Wang X, Zhu M. Machine Learning Applications in Acute Coronary Syndrome: Diagnosis, Outcomes and Management. Adv Ther 2025; 42:636-665. [PMID: 39641854 DOI: 10.1007/s12325-024-03060-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/18/2024] [Accepted: 08/20/2024] [Indexed: 12/07/2024]
Abstract
Acute coronary syndrome (ACS) is a leading cause of death worldwide. Prompt and accurate diagnosis of acute myocardial infarction (AMI) or ACS is crucial for improved management and prognosis of patients. The rapid growth of machine learning (ML) research has significantly enhanced our understanding of ACS. Most studies have focused on applying ML to detect ACS, predict prognosis, manage treatment, identify risk factors, and discover potential biomarkers, particularly using data from electrocardiograms (ECGs), electronic medical records (EMRs), imaging, and omics as the main data modality. Additionally, integrating ML with smart devices such as wearables, smartphones, and sensor technology enables real-time dynamic assessments, enhancing clinical care for patients with ACS. This review provided an overview of the workflow and key concepts of ML as they relate to ACS. It then provides an overview of current ML algorithms used for ACS diagnosis, prognosis, identification of potential risk biomarkers, and management. Furthermore, we discuss the current challenges faced by ML algorithms in this field and how they might be addressed in the future, especially in the context of medicine.
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Affiliation(s)
- Shanshan Nie
- Department of Cardiovascular Disease, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450000, Henan, China
| | - Shan Zhang
- Department of Digestive Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China
| | - Yuhang Zhao
- Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
| | - Xun Li
- College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan, China
| | - Huaming Xu
- School of Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan, China
| | - Yongxia Wang
- Department of Cardiovascular Disease, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450000, Henan, China
| | - Xinlu Wang
- Department of Cardiovascular Disease, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450000, Henan, China.
| | - Mingjun Zhu
- Department of Cardiovascular Disease, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450000, Henan, China.
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11
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Sandhu MRS, Tickoo M, Bardia A. Data Science and Geriatric Anesthesia Research: Opportunity and Challenges. Clin Geriatr Med 2025; 41:101-116. [PMID: 39551536 DOI: 10.1016/j.cger.2024.03.009] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/19/2024]
Abstract
With an increase in geriatric population undergoing surgical procedures, research focused on enhancing their perioperative outcomes is of paramount importance. Currently, most of the evidence-based medicine protocols are driven by studies concentrating on adults encompassing all adult age groups. Given the alterations in physiology with aging, geriatric patients respond differently to anesthetics and, therefore, require specific research initiatives to further expound on the same. Large databases and the development of sophisticated analytic tools can provide meaningful insights into this. Here, we discuss a few research opportunities and challenges that data scientists face when focusing on geriatric perioperative research.
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Affiliation(s)
- Mani Ratnesh S Sandhu
- Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
| | - Mayanka Tickoo
- Division of Pulmonary, Department of Medicine, Critical Care and Sleep Medicine, Tufts Medical Center, Biewend Building, 3Road Floor, 260 Tremont Street, Boston, MA 02118, USA
| | - Amit Bardia
- Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 06520, USA.
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Ma Y, Yang X, Weng C, Wang X, Zhang B, Liu Y, Wang R, Bao Z, Yang P, Zhang H, Liu Y. Unsupervised machine learning model for phenogroup-based stratification in acute type A aortic dissection to identify postoperative acute gastrointestinal injury. Front Cardiovasc Med 2025; 11:1514751. [PMID: 39872883 PMCID: PMC11770000 DOI: 10.3389/fcvm.2024.1514751] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/21/2024] [Accepted: 12/30/2024] [Indexed: 01/30/2025] Open
Abstract
Objective We aimed to explore the application value of unsupervised machine learning in identifying acute gastrointestinal injury (AGI) after extracorporeal circulation for acute type A aortic dissection (ATAAD). Methods Patients who underwent extracorporeal circulation for ATAAD at the First Hospital of Lanzhou University from January 2016 to January 2021 were included. Unsupervised machine learning algorithm was used to stratify patients into different phenogroups according to the similarity of their clinical features and laboratory test results. The differences in the incidence of perioperative AGI and other adverse events among different phenogroups were compared. Logistic regression was used to analyze the high-risk factors for AGI in each phenogroups and random forest (RF) algorithms were used to construct diagnostic models for AGI in different phenogroups. Results A total of 188 patients were included, with 166 males and 22 females. Unsupervised Machine Learning stratified patients into three phenogroups (phenogroup A, B, and C). Compared with other phenogroups, phenogroup B patients were older (P < 0.01), had higher preoperative lactate and D-dimer levels, and had the highest incidence of AGI (52.5%, P < 0.001) and in-hospital mortality (18.6%, P = 0.002). The random forest model showed that the top four risk factors for AGI in phenogroup B were cardiopulmonary bypass time, operation time, aortic clamping time, and ventilator time, which were significantly different from other phenogroups. The areas under the curve (AUCs) for diagnosing postoperative AGI of phenogroup A, B, and C were 0.943 (0.854-0.992), 0.990 (0.966-1.000), and 0.964 (0.899-0.997) using the RF model, respectively. Conclusion Phenogroup stratification based on unsupervised learning can accurately identify high-risk populations for postoperative AGI in ATAAD, providing a new approach for implementing individualized preventive and therapeutic measures in clinical practice.
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Affiliation(s)
- Yuhu Ma
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Xiaofang Yang
- Department of Cardiac Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Chenxiang Weng
- The First School of Clinical Medicine, Lanzhou University, Lanzhou, China
| | - Xiaoqing Wang
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Baoping Zhang
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Ying Liu
- The First School of Clinical Medicine, Lanzhou University, Lanzhou, China
| | - Rui Wang
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Zhenxing Bao
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Peining Yang
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Hong Zhang
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
| | - Yatao Liu
- Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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Shi Y, Wang X, Chen S, Zhao Y, Wang Y, Sheng X, Qi X, Zhou L, Feng Y, Liu J, Wang C, Xing K. Identification of key genes affecting intramuscular fat deposition in pigs using machine learning models. Front Genet 2025; 15:1503148. [PMID: 39834552 PMCID: PMC11743517 DOI: 10.3389/fgene.2024.1503148] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/28/2024] [Accepted: 12/09/2024] [Indexed: 01/22/2025] Open
Abstract
Intramuscular fat (IMF) is an important indicator for evaluating meat quality. Transcriptome sequencing (RNA-seq) is widely used for the study of IMF deposition. Machine learning (ML) is a new big data fitting method that can effectively fit complex data, accurately identify samples and genes, and it plays an important role in omics research. Therefore, this study aimed to analyze RNA-seq data by ML method to identify differentially expressed genes (DEGs) affecting IMF deposition in pigs. In this study, a total of 74 RNA-seq data from muscle tissue samples were used. A total of 155 DEGs were identified using a limma package between the two groups. 100 and 11 significant genes were identified by support vector machine recursive feature elimination (SVM-RFE) and random forest (RF) models, respectively. A total of six intersecting genes were in both models. KEGG pathway enrichment analysis of the intersecting genes revealed that these genes were enriched in pathways associated with lipid deposition. These pathways include α-linolenic acid metabolism, linoleic acid metabolism, ether lipid metabolism, arachidonic acid metabolism, and glycerophospholipid metabolism. Four key genes affecting intramuscular fat deposition, PLA2G6, MPV17, NUDT2, and ND4L, were identified based on significant pathways. The results of this study are important for the elucidation of the molecular regulatory mechanism of intramuscular fat deposition and the effective improvement of IMF content in pigs.
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Affiliation(s)
- Yumei Shi
- College of Animal Science and Technology, China Agricultural University, Beijing, China
- College of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
| | - Xini Wang
- College of Animal Science and Technology, China Agricultural University, Beijing, China
| | | | - Yanhui Zhao
- College of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
| | - Yan Wang
- College of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
| | - Xihui Sheng
- College of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
| | - Xiaolong Qi
- College of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
| | - Lei Zhou
- College of Animal Science and Technology, China Agricultural University, Beijing, China
| | - Yu Feng
- College of Animal Science and Technology, China Agricultural University, Beijing, China
| | - Jianfeng Liu
- College of Animal Science and Technology, China Agricultural University, Beijing, China
| | - Chuduan Wang
- College of Animal Science and Technology, China Agricultural University, Beijing, China
| | - Kai Xing
- College of Animal Science and Technology, China Agricultural University, Beijing, China
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Çelik E, Turgut MA, Aydoğan M, Kılınç M, Toktaş İ, Akelma H. Comparison of AI applications and anesthesiologist's anesthesia method choices. BMC Anesthesiol 2025; 25:2. [PMID: 39754097 PMCID: PMC11697632 DOI: 10.1186/s12871-024-02882-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/11/2024] [Accepted: 12/27/2024] [Indexed: 01/07/2025] Open
Abstract
BACKGROUND In medicine, Artificial intelligence has begun to be utilized in nearly every domain, from medical devices to the interpretation of imaging studies. There is still a need for more experience and more studies related to the comprehensive use of AI in medicine. The aim of the present study is to evaluate the ability of AI to make decisions regarding anesthesia methods and to compare the most popular AI programs from this perspective. METHODS The study included orthopedic patients over 18 years of age scheduled for limb surgery within a 1-month period. Patients classified as ASA I-III who were evaluated in the anesthesia clinic during the preoperative period were included in the study. The anesthesia method preferred by the anesthesiologist during the operation and the patient's demographic data, comorbidities, medications, and surgical history were recorded. The obtained patient data were discussed as if presenting a patient scenario using the free versions of the ChatGPT, Copilot, and Gemini applications by a different anesthesiologist who did not perform the operation. RESULTS Over the course of 1 month, a total of 72 patients were enrolled in the study. It was observed that both the anesthesia specialists and the Gemini application chose spinal anesthesia for the same patient in 68.5% of cases. This rate was higher compared to the other AI applications. For patients taking medication, it was observed that the Gemini application presented choices that were highly compatible (85.7%) with the anesthesiologists' preferences. CONCLUSION AI cannot fully master the guidelines and exceptional and specific cases that arrive in the course of medical treatment. Thus, we believe that AI can serve as a valuable assistant rather than replacing doctors.
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Affiliation(s)
- Enes Çelik
- Department of Anesthesiology and Reanimation, Mardin Artuklu University School of Medicine, Diyarbakır Road, Artuklu, Mardin, 47100, Turkey.
| | - Mehmet Ali Turgut
- Mardin Training and Research Hospital, Anesthesia Clinic, Mardin, Turkey
| | - Mesut Aydoğan
- Private Baglar Hospital, Anesthesia Clinic, Diyarbakir, Turkey
| | - Metin Kılınç
- Department of Anesthesiology and Reanimation, Mardin Artuklu University School of Medicine, Diyarbakır Road, Artuklu, Mardin, 47100, Turkey
| | - İzzettin Toktaş
- Department of Public Health, Faculty of Medicine, Mardin Artuklu University, Mardin, Turkey
| | - Hakan Akelma
- Department of Anesthesiology and Reanimation, Mardin Artuklu University School of Medicine, Diyarbakır Road, Artuklu, Mardin, 47100, Turkey
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Glicksman M, Wang S, Yellapragada S, Robinson C, Orhurhu V, Emerick T. Artificial intelligence and pain medicine education: Benefits and pitfalls for the medical trainee. Pain Pract 2025; 25:e13428. [PMID: 39588809 DOI: 10.1111/papr.13428] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/27/2024]
Abstract
OBJECTIVES Artificial intelligence (AI) represents an exciting and evolving technology that is increasingly being utilized across pain medicine. Large language models (LLMs) are one type of AI that has become particularly popular. Currently, there is a paucity of literature analyzing the impact that AI may have on trainee education. As such, we sought to assess the benefits and pitfalls that AI may have on pain medicine trainee education. Given the rapidly increasing popularity of LLMs, we particularly assessed how these LLMs may promote and hinder trainee education through a pilot quality improvement project. MATERIALS AND METHODS A comprehensive search of the existing literature regarding AI within medicine was performed to identify its potential benefits and pitfalls within pain medicine. The pilot project was approved by UPMC Quality Improvement Review Committee (#4547). Three of the most commonly utilized LLMs at the initiation of this pilot study - ChatGPT Plus, Google Bard, and Bing AI - were asked a series of multiple choice questions to evaluate their ability to assist in learner education within pain medicine. RESULTS Potential benefits of AI within pain medicine trainee education include ease of use, imaging interpretation, procedural/surgical skills training, learner assessment, personalized learning experiences, ability to summarize vast amounts of knowledge, and preparation for the future of pain medicine. Potential pitfalls include discrepancies between AI devices and associated cost-differences, correlating radiographic findings to clinical significance, interpersonal/communication skills, educational disparities, bias/plagiarism/cheating concerns, lack of incorporation of private domain literature, and absence of training specifically for pain medicine education. Regarding the quality improvement project, ChatGPT Plus answered the highest percentage of all questions correctly (16/17). Lowest correctness scores by LLMs were in answering first-order questions, with Google Bard and Bing AI answering 4/9 and 3/9 first-order questions correctly, respectively. Qualitative evaluation of these LLM-provided explanations in answering second- and third-order questions revealed some reasoning inconsistencies (e.g., providing flawed information in selecting the correct answer). CONCLUSIONS AI represents a continually evolving and promising modality to assist trainees pursuing a career in pain medicine. Still, limitations currently exist that may hinder their independent use in this setting. Future research exploring how AI may overcome these challenges is thus required. Until then, AI should be utilized as supplementary tool within pain medicine trainee education and with caution.
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Affiliation(s)
- Michael Glicksman
- Department of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, USA
| | - Sheri Wang
- Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, USA
| | - Samir Yellapragada
- University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
| | - Christopher Robinson
- Department of Anesthesiology, Perioperative, and Pain Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA
| | - Vwaire Orhurhu
- University of Pittsburgh Medical Center (UPMC), Susquehanna, Williamsport, Pennsylvania, USA
- MVM Health, East Stroudsburg, Pennsylvania, USA
| | - Trent Emerick
- Department of Anesthesiology and Perioperative Medicine, Chronic Pain Division, University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, USA
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Ventresca HC, Davis HT, Gauthier CW, Kung J, Park JS, Strasser NL, Gonzalez TA, Jackson JB. ChatGPT-4 Effectively Responds to Common Patient Questions on Total Ankle Arthroplasty: A Surgeon-Based Assessment of AI in Patient Education. FOOT & ANKLE ORTHOPAEDICS 2025; 10:24730114251322784. [PMID: 40160854 PMCID: PMC11951880 DOI: 10.1177/24730114251322784] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/02/2025] Open
Abstract
Background Patient reliance on internet resources for clinical information has steadily increased. The recent widespread accessibility of artificial intelligence (AI) tools like ChatGPT has increased patient reliance on these resources while also raising concerns about the accuracy, reliability, and appropriateness of the information they provide. Previous studies have evaluated ChatGPT and found it could accurately respond to questions on common surgeries, such as total hip arthroplasty, but is untested for uncommon procedures like total ankle arthroplasty (TAA). This study evaluates ChatGPT-4's performance in answering patient questions on TAA and further explores the opportunity for physician involvement in guiding the implementation of this technology. Methods Twelve commonly asked patient questions regarding TAA were collated from established sources and posed to ChatGPT-4 without additional input. Four fellowship-trained surgeons independently rated the responses using a 1-4 scale, assessing accuracy and need for clarification. Interrater reliability, divergence, and trends in response content were analyzed to evaluate consistency across responses. Results The mean score across all responses was 1.8, indicating an overall satisfactory performance by ChatGPT-4. Ratings were consistently good on factual questions, such as infection risk and success rates, whereas questions requiring nuanced information, such as postoperative protocols and prognosis, received poorer ratings. Significant variability was observed among surgeons' ratings and between questions, reflecting differences in interpretation and expectations. Conclusion ChatGPT-4 demonstrates its potential to reliably provide discrete information for uncommon procedures such as TAA, but it lacks the capability to effectively respond to questions requiring patient- or surgeon-specific insight. This limitation, paired with the growing reliance on AI, highlights the need for AI tools tailored to specific clinical practices to enhance accuracy and relevance in patient education.
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Affiliation(s)
- Heidi C. Ventresca
- Department of Orthopaedic Surgery, School of Medicine, University of South Carolina, Columbia, SC, USA
| | - Harley T. Davis
- Department of Orthopaedic Surgery, Prisma Health–Midlands, Columbia, SC, USA
| | - Chase W. Gauthier
- Department of Orthopaedic Surgery, School of Medicine, University of South Carolina, Columbia, SC, USA
| | - Justin Kung
- Department of Orthopaedic Surgery, School of Medicine, University of South Carolina, Columbia, SC, USA
| | - Joseph S. Park
- Department of Orthopaedic Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
| | - Nicholas L. Strasser
- Department of Orthopaedic Surgery, School of Medicine, Vanderbilt University, Nashville, TN, USA
| | - Tyler A. Gonzalez
- Department of Orthopaedic Surgery, Prisma Health–Midlands, Columbia, SC, USA
| | - J. Benjamin Jackson
- Department of Orthopaedic Surgery, School of Medicine, University of South Carolina, Columbia, SC, USA
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Xie BH, Li TT, Ma FT, Li QJ, Xiao QX, Xiong LL, Liu F. Artificial intelligence in anesthesiology: a bibliometric analysis. Perioper Med (Lond) 2024; 13:121. [PMID: 39716340 DOI: 10.1186/s13741-024-00480-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/02/2024] [Accepted: 12/10/2024] [Indexed: 12/25/2024] Open
Abstract
The application of artificial intelligence (AI) in anesthesiology has become increasingly widespread. However, no previous study has analyzed this field from the bibliometric analysis dimension. The objective of this paper was to assess the global research trends in AI in anesthesiology using bibliometric software. Literatures relevant to AI and anesthesiology were retrieved from the Web of Science until 10 April 2024 and were visualized and analyzed using Excel, CiteSpace, and VOSviewer. After screening, 491 studies were included in the final bibliometric analysis. The growth rate of publications, countries, institutions, authors, journals, literature co-citations, and keyword co-occurrences was computed. The number of publications increased annually since 2018, with the most significant contributions from the USA, China, and England. The top 3 institutions were Yuan Ze University, National Taiwan University, and Brunel University London. The top three journals were Anesthesia & Analgesia, BMC Anesthesiology, and the British Journal of Anaesthesia. The researches on the application of AI in predicting hypotension have been extensive and represented a hotspot and frontier. In terms of keyword co-occurrence cluster analysis, keywords were categorized into four clusters: ultrasound-guided regional anesthesia, postoperative pain and airway management, prediction, depth of anesthesia (DoA), and intraoperative drug infusion. This analysis provides a systematic analysis on the literature regarding the AI-related research in the field of anesthesiology, which may help researchers and anesthesiologists better understand the research trend of anesthesia-related AI.
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Affiliation(s)
- Bi-Hua Xie
- Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China
- Department of Anesthesiology, The Third People's Hospital of Yibin, Yibin, 644000, Sichuan, China
| | - Ting-Ting Li
- Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China
| | - Feng-Ting Ma
- Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China
- Department of Anesthesiology, The First People's Hospital of Shuangliu District, Chengdu, 610041, Sichuan, China
| | - Qi-Jun Li
- School of Pharmacy, Zunyi Medical University, Zunyi, 563000, Guizhou, China
| | - Qiu-Xia Xiao
- Department of Anesthesiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563000, Guizhou, China
| | - Liu-Lin Xiong
- Department of Anesthesiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563000, Guizhou, China.
| | - Fei Liu
- Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
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Choudhary N, Gupta A, Gupta N. Artificial intelligence and robotics in regional anesthesia. World J Methodol 2024; 14:95762. [PMID: 39712560 PMCID: PMC11287539 DOI: 10.5662/wjm.v14.i4.95762] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/17/2024] [Revised: 06/03/2024] [Accepted: 06/13/2024] [Indexed: 07/26/2024] Open
Abstract
Artificial intelligence (AI) technology is vital for practitioners to incorporate AI and robotics in day-to-day regional anesthesia practice. Recent literature is encouraging on its applications in regional anesthesia, but the data are limited. AI can help us identify and guide the needle tip precisely to the location. This may help us reduce the time, improve precision, and reduce the associated side effects of improper distribution of drugs. In this article, we discuss the potential roles of AI and robotics in regional anesthesia.
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Affiliation(s)
- Nitin Choudhary
- Department of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India
| | - Anju Gupta
- Department of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India
| | - Nishkarsh Gupta
- Department of Onco-Anesthesiology and Palliative Medicine, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India
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Jin Y, Liang L, Li J, Xu K, Zhou W, Li Y. Artificial intelligence and glaucoma: a lucid and comprehensive review. Front Med (Lausanne) 2024; 11:1423813. [PMID: 39736974 PMCID: PMC11682886 DOI: 10.3389/fmed.2024.1423813] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/26/2024] [Accepted: 11/25/2024] [Indexed: 01/01/2025] Open
Abstract
Glaucoma is a pathologically irreversible eye illness in the realm of ophthalmic diseases. Because it is difficult to detect concealed and non-obvious progressive changes, clinical diagnosis and treatment of glaucoma is extremely challenging. At the same time, screening and monitoring for glaucoma disease progression are crucial. Artificial intelligence technology has advanced rapidly in all fields, particularly medicine, thanks to ongoing in-depth study and algorithm extension. Simultaneously, research and applications of machine learning and deep learning in the field of glaucoma are fast evolving. Artificial intelligence, with its numerous advantages, will raise the accuracy and efficiency of glaucoma screening and diagnosis to new heights, as well as significantly cut the cost of diagnosis and treatment for the majority of patients. This review summarizes the relevant applications of artificial intelligence in the screening and diagnosis of glaucoma, as well as reflects deeply on the limitations and difficulties of the current application of artificial intelligence in the field of glaucoma, and presents promising prospects and expectations for the application of artificial intelligence in other eye diseases such as glaucoma.
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Affiliation(s)
| | - Lina Liang
- Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing, China
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Yang Y, Shen H, Chen K, Li X. From pixels to patients: the evolution and future of deep learning in cancer diagnostics. Trends Mol Med 2024:S1471-4914(24)00310-1. [PMID: 39665958 DOI: 10.1016/j.molmed.2024.11.009] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/31/2024] [Revised: 10/15/2024] [Accepted: 11/14/2024] [Indexed: 12/13/2024]
Abstract
Deep learning has revolutionized cancer diagnostics, shifting from pixel-based image analysis to more comprehensive, patient-centric care. This opinion article explores recent advancements in neural network architectures, highlighting their evolution in biomedical research and their impact on medical imaging interpretation and multimodal data integration. We emphasize the need for domain-specific artificial intelligence (AI) systems capable of handling complex clinical tasks, advocating for the development of multimodal large language models that can integrate diverse data sources. These models have the potential to significantly enhance the precision and efficiency of cancer diagnostics, transforming AI from a supplementary tool into a core component of clinical decision-making, ultimately improving patient outcomes and advancing cancer care.
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Affiliation(s)
- Yichen Yang
- Tianjin Cancer Institute, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China
| | - Hongru Shen
- Tianjin Cancer Institute, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China
| | - Kexin Chen
- Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology of Tianjin, Key Laboratory of Prevention and Control of Human Major Diseases in Ministry of Education, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.
| | - Xiangchun Li
- Tianjin Cancer Institute, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.
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He X, Li T, Wang X. Research progress on the depth of anesthesia monitoring based on the electroencephalogram. IBRAIN 2024; 11:32-43. [PMID: 40103697 PMCID: PMC11911112 DOI: 10.1002/ibra.12186] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 05/22/2024] [Revised: 10/17/2024] [Accepted: 11/05/2024] [Indexed: 03/20/2025]
Abstract
General anesthesia typically involves three key components: amnesia, analgesia, and immobilization. Monitoring the depth of anesthesia (DOA) during surgery is crucial for personalizing anesthesia regimens and ensuring precise drug delivery. Since general anesthetics act primarily on the brain, this organ becomes the target for monitoring DOA. Electroencephalogram (EEG) can record the electrical activity generated by various brain tissues, enabling anesthesiologists to monitor the DOA from real-time changes in a patient's brain activity during surgery. This monitoring helps to optimize anesthesia medication, prevent intraoperative awareness, and reduce the incidence of cardiovascular and other adverse events, contributing to anesthesia safety. Different anesthetic drugs exert different effects on the EEG characteristics, which have been extensively studied in commonly used anesthetic drugs. However, due to the limited understanding of the biological basis of consciousness and the mechanisms of anesthetic drugs acting on the brain, combined with the effects of various factors on existing EEG monitors, DOA cannot be accurately expressed via EEG. The lack of patient reactivity during general anesthesia does not necessarily indicate unconsciousness, highlighting the importance of distinguishing the mechanisms of consciousness and conscious connectivity when monitoring perioperative anesthesia depth. Although EEG is an important means of monitoring DOA, continuous optimization is necessary to extract characteristic information from EEG to monitor DOA, and EEG monitoring technology based on artificial intelligence analysis is an emerging research direction.
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Affiliation(s)
- Xiaolan He
- Department of Anesthesiology, West China HospitalSichuan UniversityChengduChina
| | - Tingting Li
- Department of Anesthesiology, West China HospitalSichuan UniversityChengduChina
| | - Xiao Wang
- Department of Anesthesiology, West China HospitalSichuan UniversityChengduChina
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Brook K, Wilde M, Vannucci A, Agarwala AV. Beyond adverse events in anesthesiology: 'unanticipated events' and strategies for improved reporting. Curr Opin Anaesthesiol 2024; 37:727-735. [PMID: 39248008 DOI: 10.1097/aco.0000000000001425] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 09/10/2024]
Abstract
PURPOSE OF REVIEW Patient safety in anesthesiology has advanced significantly over the past several decades. The current process of improving care is often based on studying adverse events (AEs) and near misses. However, there is a wealth of information not captured by focusing solely on these events, potentially resulting in missed opportunities for care improvements. RECENT FINDINGS We review terms such as AEs and nonroutine events (NREs), and introduce the concept of unanticipated events (UEs), defined as events that deviate from intended care that may/may not have been caused by error, may/may not be preventable, and may/may not have caused injury to a patient. UEs incorporate AEs in addition to many other anesthetic events not routinely tracked, allowing for trend analysis over time and the identification of additional opportunities for quality improvement. We review both automated and self-reporting tools that currently exist to capture this often-neglected wealth of data. Finally, we discuss the responsibility of quality/safety leaders for data monitoring. SUMMARY Consistent reporting and monitoring for trends related to UEs could allow departments to identify risks and mitigate harm before it occurs. We review various proposed methods to expand data collection, and recommend anesthesia practices pursue UE tracking through department-specific reporting interfaces.
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Affiliation(s)
- Karolina Brook
- Department of Anesthesiology, Boston Medical Center
- Department of Anesthesiology, Boston University Chobanian & Avedisian School of Medicine, Boston
| | - Molly Wilde
- Boston College, Chestnut Hill, Massachusetts
| | - Andrea Vannucci
- Department of Anesthesia, Carver College of Medicine, University of Iowa, Iowa City, Iowa
| | - Aalok V Agarwala
- Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital
- Harvard Medical School, Boston, Massachusetts, USA
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Tewfik G, Rivoli S, Methangkool E. The electronic health record: does it enhance or distract from patient safety? Curr Opin Anaesthesiol 2024; 37:676-682. [PMID: 39248015 DOI: 10.1097/aco.0000000000001429] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 09/10/2024]
Abstract
PURPOSE OF REVIEW The electronic health record (EHR) is an invaluable tool that may be used to improve patient safety. With a variety of different features, such as clinical decision support and computerized physician order entry, it has enabled improvement of patient care throughout medicine. EHR allows for built-in reminders for such items as antibiotic dosing and venous thromboembolism prophylaxis. RECENT FINDINGS In anesthesiology, EHR often improves patient safety by eliminating the need for reliance on manual documentation, by facilitating information transfer and incorporating predictive models for such items as postoperative nausea and vomiting. The use of EHR has been shown to improve patient safety in specific metrics such as using checklists or information transfer amongst clinicians; however, limited data supports that it reduces morbidity and mortality. SUMMARY There are numerous potential pitfalls associated with EHR use to improve patient safety, as well as great potential for future improvement.
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Affiliation(s)
| | - Steven Rivoli
- Mount Sinai School of Medicine: Icahn School of Medicine at Mount Sinai
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24
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Florquin R, Florquin R, Schmartz D, Dony P, Briganti G. Pediatric cardiac surgery: machine learning models for postoperative complication prediction. J Anesth 2024; 38:747-755. [PMID: 39028323 DOI: 10.1007/s00540-024-03377-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/08/2023] [Accepted: 07/04/2024] [Indexed: 07/20/2024]
Abstract
PURPOSE Managing children undergoing cardiac surgery with cardiopulmonary bypass (CPB) presents a significant challenge for anesthesiologists. Machine Learning (ML)-assisted tools have the potential to enhance the recognition of patients at risk of complications and predict potential issues, ultimately improving outcomes. METHODS We evaluated the prediction capacity of six models, ranging from logistic regression to support vector machine, using a dataset comprising 33 variables and 1364 subjects. The Area Under the Curve (AUC) and the F1 score served as the primary evaluation metrics. Our primary objectives were twofold: first, to develop an effective prediction model, and second, to create a user-friendly comprehensive model for identifying high-risk patients. RESULTS The logistic regression model demonstrated the highest effectiveness, achieving an AUC of 83.65%, and an F1 score of 0.7296, with balanced sensitivity and specificity of 77.94% and 76.47%, respectively. In comparison, the comprehensive three-layer decision tree model achieved an AUC of 72.84%, with sensitivity (79.41%) comparable to more complex models. CONCLUSION Our machine learning-assisted tools provide an additional perspective and enhance the predictive capabilities of traditional scoring methods. These tools can assist anesthesiologists in making well-informed decisions. Furthermore, we have successfully demonstrated the feasibility of creating a practical white-box model. The next steps involve conducting clinical validation and multicenter cross-validation. TRIAL REGISTRATION NCT05537168.
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Affiliation(s)
- Rémi Florquin
- Department of Anesthesiology, CHU Charleroi, Chaussée de Bruxelles 140, 6042, Lodelinsart, Belgium.
- Chair of Artificial Intelligence and Digital Medicine, Mons University, 7000, Mons, Belgium.
| | | | - Denis Schmartz
- Department of Anesthesiology, Hôpital Universitaire de Bruxelles (H.U.B), Université Libre de Bruxelles, 1070, Brussels, Belgium
| | - Philippe Dony
- Department of Anesthesiology, CHU Charleroi, Chaussée de Bruxelles 140, 6042, Lodelinsart, Belgium
| | - Giovanni Briganti
- Chair of Artificial Intelligence and Digital Medicine, Mons University, 7000, Mons, Belgium
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Yang JM, Chen BJ, Li RY, Huang BQ, Zhao MH, Liu PR, Zhang JY, Ye ZW. Artificial Intelligence in Medical Metaverse: Applications, Challenges, and Future Prospects. Curr Med Sci 2024; 44:1113-1122. [PMID: 39673002 DOI: 10.1007/s11596-024-2960-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/23/2024] [Accepted: 10/28/2024] [Indexed: 12/15/2024]
Abstract
The medical metaverse is a combination of medicine, computer science, information technology and other cutting-edge technologies. It redefines the method of information interaction about doctor-patient communication, medical education and research through the integration of medical data, knowledge and services in a virtual environment. Artificial intelligence (AI) is a discipline that uses computer technology to study and develop human intelligence. AI has infiltrated every aspect of medical metaverse and is deeply integrated with the technologies that build medical metaverse, such as large language models (LLMs), digital twins, blockchain and extended reality (including VR/AR/XR). AI has become an integral part of the medical metaverse building process. Moreover, AI also provides richer medical metaverse functions, including diagnosis, education, and consulting. This paper aims to introduce how AI supports the development of medical metaverse, including its specific application scenarios, shortcomings and future development. Our goal is to contribute to the advancement of more sophisticated and intelligent medical methods.
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Affiliation(s)
- Jia-Ming Yang
- Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
| | - Bao-Jun Chen
- Department of Orthopedics, the People's Hospital of Liaoning Province, Shenyang, 110000, China
| | - Rui-Yuan Li
- Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
| | - Bi-Qiang Huang
- Chengdu Hua Yu Tianfu Digital Technology Co., Ltd., Chengdu, 610000, China
| | - Mo-Han Zhao
- Chengdu Hua Yu Tianfu Digital Technology Co., Ltd., Chengdu, 610000, China
| | - Peng-Ran Liu
- Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
| | - Jia-Yao Zhang
- Department of Orthopedics, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350013, China.
| | - Zhe-Wei Ye
- Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
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Mehta D, Gonzalez XT, Huang G, Abraham J. Machine learning-augmented interventions in perioperative care: a systematic review and meta-analysis. Br J Anaesth 2024; 133:1159-1172. [PMID: 39322472 PMCID: PMC11589382 DOI: 10.1016/j.bja.2024.08.007] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/03/2024] [Revised: 08/01/2024] [Accepted: 08/05/2024] [Indexed: 09/27/2024] Open
Abstract
BACKGROUND We lack evidence on the cumulative effectiveness of machine learning (ML)-driven interventions in perioperative settings. Therefore, we conducted a systematic review to appraise the evidence on the impact of ML-driven interventions on perioperative outcomes. METHODS Ovid MEDLINE, CINAHL, Embase, Scopus, PubMed, and ClinicalTrials.gov were searched to identify randomised controlled trials (RCTs) evaluating the effectiveness of ML-driven interventions in surgical inpatient populations. The review was registered with PROSPERO (CRD42023433163) and conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Meta-analysis was conducted for outcomes with two or more studies using a random-effects model, and vote counting was conducted for other outcomes. RESULTS Among 13 included RCTs, three types of ML-driven interventions were evaluated: Hypotension Prediction Index (HPI) (n=5), Nociception Level Index (NoL) (n=7), and a scheduling system (n=1). Compared with the standard care, HPI led to a significant decrease in absolute hypotension (n=421, P=0.003, I2=75%) and relative hypotension (n=208, P<0.0001, I2=0%); NoL led to significantly lower mean pain scores in the post-anaesthesia care unit (PACU) (n=191, P=0.004, I2=19%). NoL showed no significant impact on intraoperative opioid consumption (n=339, P=0.31, I2=92%) or PACU opioid consumption (n=339, P=0.11, I2=0%). No significant difference in hospital length of stay (n=361, P=0.81, I2=0%) and PACU stay (n=267, P=0.44, I2=0) was found between HPI and NoL. CONCLUSIONS HPI decreased the duration of intraoperative hypotension, and NoL decreased postoperative pain scores, but no significant impact on other clinical outcomes was found. We highlight the need to address both methodological and clinical practice gaps to ensure the successful future implementation of ML-driven interventions. SYSTEMATIC REVIEW PROTOCOL CRD42023433163 (PROSPERO).
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Affiliation(s)
- Divya Mehta
- Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA
| | - Xiomara T Gonzalez
- Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA
| | - Grace Huang
- Medical Education, Washington University School of Medicine, St. Louis, MO, USA
| | - Joanna Abraham
- Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA; Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University School of Medicine, St. Louis, MO, USA.
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Alsaedi AR, Alneami N, Almajnoni F, Alamri O, Aljohni K, Alrwaily MK, Eid M, Budayr A, Alrehaili MA, Alghamdi MM, Almutairi ED, Eid MH. Perceived Worries in the Adoption of Artificial Intelligence Among Healthcare Professionals in Saudi Arabia: A Cross-Sectional Survey Study. NURSING REPORTS 2024; 14:3706-3721. [PMID: 39728632 DOI: 10.3390/nursrep14040271] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/04/2024] [Revised: 11/07/2024] [Accepted: 11/14/2024] [Indexed: 12/28/2024] Open
Abstract
The use of AI in the healthcare sector is facing some formidable concerns raised by the practitioners themselves. This study aimed to establish the concerns that surround the adoption of AI among Saudi Arabian healthcare professionals. Materials and methods: This was a cross-sectional study using stratified convenience sampling from September to November 2024 across health facilities. This study included all licensed healthcare professionals practicing for at least one year, whereas interns and administrative staff were excluded from the research. Data collection was conducted through a 33-item validated questionnaire that was provided in paper form and online. The questionnaire measured AI awareness with eight items, past experience with five items, and concerns in four domains represented by 20 items. Four hundred questionnaires were distributed, and the response rate was 78.5% (n = 314). The majority of the participants were females (52.5%), Saudis (89.2%), and employees of MOH (77.1%). The mean age for the participants was 35.6 ± 7.8 years. Quantitative analysis revealed high AI awareness scores with a mean of 3.96 ± 0.167, p < 0.001, and low previous experience scores with a mean of 2.65 ± 0.292. Data management-related worries came out as the top worry, with a mean of 3.78 ± 0.259, while the poor data entry impact topped with a mean of 4.15 ± 0.801; healthcare provider-related worries with a mean of 3.71 ± 0.182; and regulation/ethics-related worries with a mean of 3.67 ± 0.145. Health professionals' main concerns about AI adoption were related to data reliability and impacts on clinical decision-making, which significantly hindered successful AI integration in healthcare. These are the particular concerns that, if addressed through robust data management protocols and enhanced processes for clinical validation, will afford the best implementation of AI technology in an optimized way to bring better quality and safety to healthcare. Quantitative validation of AI outcomes and the development of standardized integration frameworks are subjects for future research.
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Affiliation(s)
- Abdulaziz R Alsaedi
- Medical Services, National Guard Health Affairs, Madinah 40740, Saudi Arabia
| | - Nada Alneami
- Medical Services, National Guard Health Affairs, Madinah 40740, Saudi Arabia
| | - Fahad Almajnoni
- Medical Services, National Guard Health Affairs, Madinah 40740, Saudi Arabia
| | - Ohoud Alamri
- King Fahad Specialist Hospital, Ministry of Health, Tabuk 71411, Saudi Arabia
| | - Khulud Aljohni
- King Fahad Specialist Hospital, Ministry of Health, Tabuk 71411, Saudi Arabia
| | - Maha K Alrwaily
- HR Department, Ministry of Health, Turaif 91411, Saudi Arabia
| | - Meshal Eid
- King Fahad Specialist Hospital, Ministry of Health, Tabuk 71411, Saudi Arabia
| | - Abdulaziz Budayr
- King Fahad Specialist Hospital, Ministry of Health, Tabuk 71411, Saudi Arabia
| | - Maram A Alrehaili
- Minister Assistant Office, Ministry of Health, Riyadh 11176, Saudi Arabia
| | - Marha M Alghamdi
- Sharourah General Hospital, Ministry of Health, Najran 55461, Saudi Arabia
| | - Eqab D Almutairi
- Operations, National Guard Health Affairs, Dammam 11426, Saudi Arabia
| | - Mohammed H Eid
- King Fahad Specialist Hospital, Ministry of Health, Tabuk 71411, Saudi Arabia
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Uchikov P, Khalid U, Dedaj-Salad GH, Ghale D, Rajadurai H, Kraeva M, Kraev K, Hristov B, Doykov M, Mitova V, Bozhkova M, Markov S, Stanchev P. Artificial Intelligence in Breast Cancer Diagnosis and Treatment: Advances in Imaging, Pathology, and Personalized Care. Life (Basel) 2024; 14:1451. [PMID: 39598249 PMCID: PMC11595975 DOI: 10.3390/life14111451] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/20/2024] [Revised: 11/04/2024] [Accepted: 11/06/2024] [Indexed: 11/29/2024] Open
Abstract
Breast cancer is the most prevalent cancer worldwide, affecting both low- and middle-income countries, with a growing number of cases. In 2024, about 310,720 women in the U.S. are projected to receive an invasive breast cancer diagnosis, alongside 56,500 cases of ductal carcinoma in situ (DCIS). Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. About 65% of women with the BRCA1 and 45% with the BRCA2 gene variants develop breast cancer by age 70. While these genes account for 5% of breast cancers, their prevalence is higher in certain populations. Advances in early detection, personalised medicine, and AI-driven diagnostics are improving outcomes by enabling a more precise analysis, reducing recurrence, and minimising treatment side effects. Our paper aims to explore the vast applications of artificial intelligence within the diagnosis and treatment of breast cancer and how these advancements can contribute to elevating patient care as well as discussing the potential drawbacks of such integrations into modern medicine. We structured our paper as a non-systematic review and utilised Google Scholar and PubMed databases to review literature regarding the incorporation of AI in the diagnosis and treatment of non-palpable breast masses. AI is revolutionising breast cancer management by enhancing imaging, pathology, and personalised treatment. In imaging, AI can improve the detection of cancer in mammography, MRIs, and ultrasounds, rivalling expert radiologists in accuracy. In pathology, AI enhances biomarker detection, improving HER2 and Ki67 assessments. Personalised medicine benefits from AI's predictive power, aiding risk stratification and treatment response. AI also shows promise in triple-negative breast cancer management, offering better prognosis and subtype classification. However, challenges include data variability, ethical concerns, and real-world validation. Despite limitations, AI integration offers significant potential in improving breast cancer diagnosis, prognosis, and treatment outcomes.
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Affiliation(s)
- Petar Uchikov
- Department of Special Surgery, Faculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria;
| | - Usman Khalid
- Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria; (U.K.); (G.H.D.-S.); (D.G.); (H.R.)
| | - Granit Harris Dedaj-Salad
- Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria; (U.K.); (G.H.D.-S.); (D.G.); (H.R.)
| | - Dibya Ghale
- Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria; (U.K.); (G.H.D.-S.); (D.G.); (H.R.)
| | - Harney Rajadurai
- Faculty of Medicine, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria; (U.K.); (G.H.D.-S.); (D.G.); (H.R.)
| | - Maria Kraeva
- Department of Otorhinolaryngology, Medical Faculty, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria; (M.K.); (S.M.)
| | - Krasimir Kraev
- Department of Propedeutics of Internal Diseases, Medical Faculty, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria
| | - Bozhidar Hristov
- Second Department of Internal Diseases, Section “Gastroenterology”, Medical Faculty, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria;
| | - Mladen Doykov
- Department of Urology and General Medicine, Medical Faculty, Medical University of Plovdiv, 4001 Plovdiv, Bulgaria;
| | - Vanya Mitova
- University Specialized Hospital for Active Oncology Treatment “Prof. Ivan Chernozemsky”, 1756 Sofia, Bulgaria;
| | - Maria Bozhkova
- Medical College, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria;
| | - Stoyan Markov
- Department of Otorhinolaryngology, Medical Faculty, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria; (M.K.); (S.M.)
| | - Pavel Stanchev
- Clinic of Endocrinology and Metabolic Diseases, St George University Hospital, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria;
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Shukla A, Salma A, Patel D, David John J, Kantamneni R, Patel T, Kantamaneni K. Harnessing Artificial Intelligence (AI) in Anaesthesiology: Enhancing Patient Outcomes and Clinical Efficiency. Cureus 2024; 16:e73383. [PMID: 39659330 PMCID: PMC11631157 DOI: 10.7759/cureus.73383] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 11/09/2024] [Indexed: 12/12/2024] Open
Abstract
The rapid rise and potential of artificial intelligence (AI) have created growing excitement and much debate on its potential to bring transformative changes across entire industries, including the medical industry. This systematic review aims to investigate the advancements in the AI industry and its potential implementation, specifically in the field of anaesthesiology. AI has already been integrated into different areas of medicine, including diagnostic uses in radiology and pathology and therapeutic and interventional uses in cardiology and surgery. In the field of anaesthesiology, AI has made significant progress. Potential applications include personalised drug dosing, real-time monitoring of vital signs, automated anaesthesia delivery systems, and predictive analytics for adverse events. As AI technologies continue to advance and become more prevalent in medicine, clinicians across all specialities need to understand these technologies and how they can be utilised to provide safer and more efficient care. With the rapid evolution of AI and the introduction of new concepts such as machine learning (ML), deep learning (DL), and neural networks, the field of anaesthesiology is set to undergo transformative changes. In this systematic review, we examine the existing literature to explore the current state of AI in the field of anaesthesiology, along with a prospective look at potential applications in the future. Along with its various applications, we will also discuss its limitations and flaws. As the field progresses, it is crucial to thoughtfully examine the ethical aspects of using AI in anaesthesia and ensure these technologies are applied responsibly and transparently.
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Affiliation(s)
- Arnesh Shukla
- Psychiatry, St. Martinus University, Foster City, USA
| | - Ayesha Salma
- Internal Medicine, Shadan Institute of Medical Sciences, Hyderabad, IND
| | - Dev Patel
- Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, IND
| | - Jabez David John
- Surgery, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA
| | | | - Tirath Patel
- Medicine, American University of Antigua, St. John, ATG
| | - Ketan Kantamaneni
- Trauma and Orthopaedics, East Kent University Hospitals NHS Foundation Trust, Ashford, GBR
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30
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Wang Y, Hong Y. Unlocking the potential of artificial intelligence in reproductive medicine: a bibliometric analysis from 1999 to 2024. J Assist Reprod Genet 2024; 41:3245-3247. [PMID: 39264529 PMCID: PMC11621298 DOI: 10.1007/s10815-024-03251-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/13/2024] [Accepted: 09/03/2024] [Indexed: 09/13/2024] Open
Affiliation(s)
- Yi Wang
- The First School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
| | - Yanggang Hong
- The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
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31
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Labib KM, Ghumman H, Jain S, Jarstad JS. Applications of Artificial Intelligence in Ophthalmology: Glaucoma, Cornea, and Oculoplastics. Cureus 2024; 16:e73522. [PMID: 39677277 PMCID: PMC11638466 DOI: 10.7759/cureus.73522] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/31/2024] [Accepted: 11/12/2024] [Indexed: 12/17/2024] Open
Abstract
Artificial intelligence (AI) is transforming ophthalmology by leveraging machine learning (ML) and deep learning (DL) techniques, particularly artificial neural networks (ANN) and convolutional neural networks (CNN) to mimic human brain functions and enhance accuracy through data exposure. These AI systems are particularly effective in analyzing ophthalmic images for early disease detection, improving diagnostic precision, streamlining clinical workflows, and ultimately enhancing patient outcomes. This study aims to explore the specific applications and impact of AI in the fields of glaucoma, corneal diseases, and oculoplastics. This study reviews current AI technologies in ophthalmology, examining the implementation of ML and DL techniques. It evaluates AI's role in early disease detection, diagnostic accuracy, clinical workflow enhancement, and patient outcomes. AI has significantly advanced the early detection and management of various ocular conditions. In glaucoma, AI systems provide standardized, rapid identification of disease characteristics, reducing intra- and interobserver bias and workload. For corneal diseases, AI tools enhance diagnostic methods for conditions such as keratitis and keratoconus, improving early detection and treatment planning. In oculoplastics, AI assists in the diagnosis and monitoring of eyelid and orbital diseases, facilitating precise surgical planning and postoperative management. The integration of AI in ophthalmology has revolutionized eye care by enhancing diagnostic precision, streamlining clinical workflows, and improving patient outcomes. As AI technologies continue to evolve, their applications in ophthalmology are expected to expand, offering innovative solutions for the diagnosis, monitoring, treatment, and surgical outcomes of various eye conditions.
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Affiliation(s)
- Kristie M Labib
- Department of Ophthalmology, University of South Florida Morsani College of Medicine, Tampa, USA
| | - Haider Ghumman
- Department of Ophthalmology, University of South Florida Morsani College of Medicine, Tampa, USA
| | - Samyak Jain
- Department of Ophthalmology, University of South Florida Morsani College of Medicine, Tampa, USA
| | - John S Jarstad
- Department of Ophthalmology, University of South Florida Morsani College of Medicine, Tampa, USA
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32
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Allam RM, Abdelfatah D, Khalil MIM, Elsaieed MM, El Desouky ED. Medical students and house officers' perception, attitude and potential barriers towards artificial intelligence in Egypt, cross sectional survey. BMC MEDICAL EDUCATION 2024; 24:1244. [PMID: 39482613 PMCID: PMC11529482 DOI: 10.1186/s12909-024-06201-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 03/03/2024] [Accepted: 10/15/2024] [Indexed: 11/03/2024]
Abstract
BACKGROUND Artificial intelligence (AI) is one of the sectors of medical research that is expanding the fastest right now in healthcare. AI has rapidly advanced in the field of medicine, helping to treat a variety of illnesses and reducing the number of diagnostic and follow-up errors. OBJECTIVE This study aims to assess the perception and attitude towards artificial intelligence (AI) among medical students & house officers in Egypt. METHODS An online cross-sectional study was done using a questionnaire on the Google Form website. The survey collected demographic data and explored participants' perception, attitude & potential barriers towards AI. RESULTS There are 1,346 responses from Egyptian medical students (25.8%) & house officers (74.2%). Most participants have inadequate perception (76.4%) about the importance and usage of AI in the medical field, while the majority (87.4%) have a negative attitude. Multivariate analysis revealed that age is the only independent predictor of AI perception (AOR = 1.07, 95% CI 1.01-1.13). However, perception level and gender are both independent predictors of attitude towards AI (AOR = 1.93, 95% CI 1.37-2.74 & AOR = 1.80, 95% CI 1.30-2.49, respectively). CONCLUSION The study found that medical students and house officers in Egypt have an overall negative attitude towards the integration of AI technologies in healthcare. Despite the potential benefits of AI-driven digital medicine, most respondents expressed concerns about the practical application of these technologies in the clinical setting. The current study highlights the need to address the concerns of medical students and house officers towards AI integration in Egypt. A multi-pronged approach, including education, targeted training, and addressing specific concerns, is necessary to facilitate the wider adoption of AI-enabled healthcare.
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Affiliation(s)
- Rasha Mahmoud Allam
- Cancer Epidemiology & Biostatistics Department, National Cancer Institute, Cairo University, Cairo, Egypt
| | - Dalia Abdelfatah
- Cancer Epidemiology & Biostatistics Department, National Cancer Institute, Cairo University, Cairo, Egypt.
| | | | | | - Eman D El Desouky
- Cancer Epidemiology & Biostatistics Department, National Cancer Institute, Cairo University, Cairo, Egypt
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33
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Kim SG, Hwang JS, George NP, Jang YE, Kwon M, Lee SS, Lee G. Integrative Metabolome and Proteome Analysis of Cerebrospinal Fluid in Parkinson's Disease. Int J Mol Sci 2024; 25:11406. [PMID: 39518959 PMCID: PMC11547079 DOI: 10.3390/ijms252111406] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/30/2024] [Revised: 10/18/2024] [Accepted: 10/22/2024] [Indexed: 11/16/2024] Open
Abstract
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra. Recent studies have highlighted the significant role of cerebrospinal fluid (CSF) in reflecting pathophysiological PD brain conditions by analyzing the components of CSF. Based on the published literature, we created a single network with altered metabolites in the CSF of patients with PD. We analyzed biological functions related to the transmembrane of mitochondria, respiration of mitochondria, neurodegeneration, and PD using a bioinformatics tool. As the proteome reflects phenotypes, we collected proteome data based on published papers, and the biological function of the single network showed similarities with that of the metabolomic network. Then, we analyzed the single network of integrated metabolome and proteome. In silico predictions based on the single network with integrated metabolomics and proteomics showed that neurodegeneration and PD were predicted to be activated. In contrast, mitochondrial transmembrane activity and respiration were predicted to be suppressed in the CSF of patients with PD. This review underscores the importance of integrated omics analyses in deciphering PD's complex biochemical networks underlying neurodegeneration.
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Affiliation(s)
- Seok Gi Kim
- Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea
- Department of Physiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea
| | - Ji Su Hwang
- Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea
- Department of Physiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea
| | - Nimisha Pradeep George
- Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea
- Department of Physiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea
| | - Yong Eun Jang
- Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea
- Department of Physiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea
| | - Minjun Kwon
- Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea
- Department of Physiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea
| | - Sang Seop Lee
- Department of Pharmacology, Inje University College of Medicine, Busan 50834, Republic of Korea
| | - Gwang Lee
- Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea
- Department of Physiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea
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34
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Shah A, Dhiman P. Artificial intelligence in peri-operative prediction model research: are we there yet? Anaesthesia 2024; 79:1017-1022. [PMID: 38747301 DOI: 10.1111/anae.16315] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 04/26/2024] [Indexed: 09/16/2024]
Affiliation(s)
- Akshay Shah
- Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
| | - Paula Dhiman
- Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Centre for Statistics in Medicine, University of Oxford, Oxford, UK
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Al Harbi M, Alotaibi A, Alanazi A, Alsughayir F, Alharbi D, Bin Qassim A, Alkhwaiter T, Olayan L, Al Zaid M, Alsabani M. Perspectives toward the application of Artificial Intelligence in anesthesiology-related practices in Saudi Arabia: A cross-sectional study of physicians views. Health Sci Rep 2024; 7:e70099. [PMID: 39410950 PMCID: PMC11473377 DOI: 10.1002/hsr2.70099] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/11/2024] [Revised: 09/03/2024] [Accepted: 09/05/2024] [Indexed: 10/19/2024] Open
Abstract
Background and Aims The use of Artificial Intelligence (AI) relies on computer science and large datasets, with the technology mimicking human intelligence as it makes logical decisions. This study aims to assess the perceptions and experiences of anesthesiology practitioners toward AI and identify its benefits to healthcare professionals and patients, along with current and future applications of AI. Methods This cross-sectional descriptive online survey study was disseminated to physicians who work in anesthesiology practice in Saudi Arabia. Descriptive statistics were used to report the characteristics of the respondents and summarize the results of the survey. Results There were 109 responses, with 85.32% being male, 35.78% being aged 40-49 years, and 69.72% being consultant anesthesiologists. The majority of participants (73.39%) believed that AI could be used in multiple settings related to anesthesiology practice. Participants also believed that AI could facilitate access to data (76.15%), enable precise decision-making (75.23%), reduce medical errors (55.04%), reduce workload and shortage of healthcare personnel (53.21%), and allow healthcare personnel to focus on more demanding cases (69.72%). In addition, the majority of participants believed that AI can be beneficial to patients, in which 69.72% believed that AI can improve patient access to care, 77.06% believed that AI can facilitate patient education, and 65.14% believed that AI can guide patients during treatment. Lastly, 70.64% believed that AI would be beneficial to anesthesiology practices in the future. However, 61.47% claimed that their workplace has no plan for adopting AI. Conclusions The anesthesiologists showed generally positive attitudes towards AI, in spite of its limited utilization and implementation challenges. Strong beliefs exist about AI's future potential in anesthesia care and postgraduate education.
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Affiliation(s)
- Mohammed Al Harbi
- Department of Anesthesia Ministry of National Guard Health Affairs Riyadh Saudi Arabia
- King Abdullah International Medical Research Centre Riyadh Saudi Arabia
- College of Medicine King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
| | - Ahmed Alotaibi
- King Abdullah International Medical Research Centre Riyadh Saudi Arabia
- Anesthesia Technology Department, College of Applied Medical Sciences King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
| | - Amal Alanazi
- College of Medicine King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
| | - Fatimah Alsughayir
- College of Medicine King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
| | - Deema Alharbi
- College of Medicine University of Tabuk Tabuk Saudi Arabia
| | - Ahmad Bin Qassim
- College of Medicine Imam Mohammad ibn Saud Islamic University Riyadh Saudi Arabia
| | - Talal Alkhwaiter
- College of Medicine Imam Mohammad ibn Saud Islamic University Riyadh Saudi Arabia
| | - Lafi Olayan
- King Abdullah International Medical Research Centre Riyadh Saudi Arabia
- Anesthesia Technology Department, College of Applied Medical Sciences King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
| | - Manal Al Zaid
- King Abdullah International Medical Research Centre Riyadh Saudi Arabia
- College of Medicine King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
- Department of Surgery Ministry of National Guard Health Affairs Riyadh Saudi Arabia
| | - Mohmad Alsabani
- King Abdullah International Medical Research Centre Riyadh Saudi Arabia
- Anesthesia Technology Department, College of Applied Medical Sciences King Saud bin Abdulaziz University for Health Sciences Riyadh Saudi Arabia
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Green RW, Castro H. Transforming Otolaryngology-Head and Neck Surgery: The Pivotal Role of Artificial Intelligence in Clinical Workflows. Otolaryngol Clin North Am 2024; 57:909-918. [PMID: 38719713 DOI: 10.1016/j.otc.2024.04.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 09/06/2024]
Abstract
Use of artificial intelligence (AI) is expanding exponentially as it pertains to workflow operations. Otolaryngology-Head and Neck Surgery (OHNS), as with all medical fields, is just now beginning to realize the exciting upsides of AI as it relates to patient care but otolaryngologists should also be critical when considering using AI solutions. This paper highlights how AI can optimize clinical workflows in the outpatient, inpatient, and surgical settings while also discussing some of the possible drawbacks with the burgeoning technology.
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Radaviciute I, Hunn CA, Lunkiewicz J, Milovanovic P, Willms JF, Nöthiger CB, Keller E, Tscholl DW, Gasciauskaite G. Survey-based qualitative exploration of user perspectives on the philips visual patient avatar in clinical situation management. Sci Rep 2024; 14:22176. [PMID: 39333568 PMCID: PMC11437179 DOI: 10.1038/s41598-024-72338-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/12/2024] [Accepted: 09/05/2024] [Indexed: 09/29/2024] Open
Abstract
Philips Visual Patient Avatar is an innovative approach to patient monitoring. Computer-based simulation studies have shown that it can improve diagnostic accuracy and confidence while reducing perceived workload. Following its integration into clinical practice, we conducted a single-centre qualitative study at the University Hospital Zurich to explore the views of anaesthesia, post-anaesthesia and intensive care providers on their experience with the technology. We used an online survey to assess its contributions in different clinical situations. We analysed the data thematically to identify key themes. Of the 510 healthcare providers contacted, 131 (25.7%) completed the survey and 154 comments were collected. Key themes included the detection of specific vital sign changes, focusing on temperature and oxygen saturation (41.9%, 34/81 comments in the operating room; 38.6%, 17/44 comments in the intensive care unit; 10.3%, 3/29 comments in the post-anaesthesia care unit). Additionally, the technology was perceived to support daily routines and situational awareness (28.4%, 23/81 comments in the OR; 9.1%, 4/44 comments in the ICU; 10.3%, 3/29 comments in the PACU). The study provides early, but strong evidence that the Philips Visual Patient Avatar assists healthcare providers in specific clinical situations in the perioperative and critical care settings.
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Affiliation(s)
- Indre Radaviciute
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - Cynthia A Hunn
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - Justyna Lunkiewicz
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - Petar Milovanovic
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - Jan F Willms
- Neurosurgical Intensive Care Unit, Department of Neurosurgery and Institute of Intensive Care Medicine, University Hospital and University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - Christoph B Nöthiger
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - Emanuela Keller
- Neurosurgical Intensive Care Unit, Department of Neurosurgery and Institute of Intensive Care Medicine, University Hospital and University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
| | - David W Tscholl
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
| | - Greta Gasciauskaite
- Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
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Zhou P, Deng H, Zeng J, Ran H, Yu C. Unconscious classification of quantitative electroencephalogram features from propofol versus propofol combined with etomidate anesthesia using one-dimensional convolutional neural network. Front Med (Lausanne) 2024; 11:1447951. [PMID: 39359920 PMCID: PMC11445052 DOI: 10.3389/fmed.2024.1447951] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/14/2024] [Accepted: 09/05/2024] [Indexed: 10/04/2024] Open
Abstract
Objective Establishing a convolutional neural network model for the recognition of characteristic raw electroencephalogram (EEG) signals is crucial for monitoring consciousness levels and guiding anesthetic drug administration. Methods This trial was conducted from December 2023 to March 2024. A total of 40 surgery patients were randomly divided into either a propofol group (1% propofol injection, 10 mL: 100 mg) (P group) or a propofol-etomidate combination group (1% propofol injection, 10 mL: 100 mg, and 0.2% etomidate injection, 10 mL: 20 mg, mixed at a 2:1 volume ratio) (EP group). In the P group, target-controlled infusion (TCI) was employed for sedation induction, with an initial effect site concentration set at 5-6 μg/mL. The EP group received an intravenous push with a dosage of 0.2 mL/kg. Six consciousness-related EEG features were extracted from both groups and analyzed using four prediction models: support vector machine (SVM), Gaussian Naive Bayes (GNB), artificial neural network (ANN), and one-dimensional convolutional neural network (1D CNN). The performance of the models was evaluated based on accuracy, precision, recall, and F1-score. Results The power spectral density (94%) and alpha/beta ratio (72%) demonstrated higher accuracy as indicators for assessing consciousness. The classification accuracy of the 1D CNN model for anesthesia-induced unconsciousness (97%) surpassed that of the SVM (83%), GNB (81%), and ANN (83%) models, with a significance level of p < 0.05. Furthermore, the mean and mean difference ± standard error of the primary power values for the EP and P groups during the induced period were as follows: delta (23.85 and 16.79, 7.055 ± 0.817, p < 0.001), theta (10.74 and 8.743, 1.995 ± 0.7045, p < 0.02), and total power (24.31 and 19.72, 4.588 ± 0.7107, p < 0.001). Conclusion Large slow-wave oscillations, power spectral density, and the alpha/beta ratio are effective indicators of changes in consciousness during intravenous anesthesia with a propofol-etomidate combination. These indicators can aid anesthesiologists in evaluating the depth of anesthesia and adjusting dosages accordingly. The 1D CNN model, which incorporates consciousness-related EEG features, represents a promising tool for assessing the depth of anesthesia. Clinical Trial Registration https://www.chictr.org.cn/index.html.
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Affiliation(s)
- Pan Zhou
- Department of Anesthesiology, Stomatological Hospital of Chongqing Medical University, Chongqing, China
- Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China
- Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China
| | - Haixia Deng
- Department of Anesthesiology, Stomatological Hospital of Chongqing Medical University, Chongqing, China
- Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China
- Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China
| | - Jie Zeng
- Department of Anesthesiology, Stomatological Hospital of Chongqing Medical University, Chongqing, China
- Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China
- Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China
| | - Haosong Ran
- College of Artificial Intelligent, Chongqing University of Technology, Chongqing, China
| | - Cong Yu
- Department of Anesthesiology, Stomatological Hospital of Chongqing Medical University, Chongqing, China
- Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China
- Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China
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Zahoor F, Nisar A, Bature UI, Abbas H, Bashir F, Chattopadhyay A, Kaushik BK, Alzahrani A, Hussin FA. An overview of critical applications of resistive random access memory. NANOSCALE ADVANCES 2024:d4na00158c. [PMID: 39263252 PMCID: PMC11382421 DOI: 10.1039/d4na00158c] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/26/2024] [Accepted: 08/10/2024] [Indexed: 09/13/2024]
Abstract
The rapid advancement of new technologies has resulted in a surge of data, while conventional computers are nearing their computational limits. The prevalent von Neumann architecture, where processing and storage units operate independently, faces challenges such as data migration through buses, leading to decreased computing speed and increased energy loss. Ongoing research aims to enhance computing capabilities through the development of innovative chips and the adoption of new system architectures. One noteworthy advancement is Resistive Random Access Memory (RRAM), an emerging memory technology. RRAM can alter its resistance through electrical signals at both ends, retaining its state even after power-down. This technology holds promise in various areas, including logic computing, neural networks, brain-like computing, and integrated technologies combining sensing, storage, and computing. These cutting-edge technologies offer the potential to overcome the performance limitations of traditional architectures, significantly boosting computing power. This discussion explores the physical mechanisms, device structure, performance characteristics, and applications of RRAM devices. Additionally, we delve into the potential future adoption of these technologies at an industrial scale, along with prospects and upcoming research directions.
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Affiliation(s)
- Furqan Zahoor
- Department of Computer Engineering, College of Computer Sciences and Information Technology, King Faisal University Saudi Arabia
| | - Arshid Nisar
- Department of Electronics and Communication Engineering, Indian Institute of Technology Roorkee India
| | - Usman Isyaku Bature
- Department of Electrical and Electronics Engineering, Universiti Teknologi Petronas Malaysia
| | - Haider Abbas
- Department of Nanotechnology and Advanced Materials Engineering, Sejong University Seoul 143-747 Republic of Korea
| | - Faisal Bashir
- Department of Computer Engineering, College of Computer Sciences and Information Technology, King Faisal University Saudi Arabia
| | - Anupam Chattopadhyay
- College of Computing and Data Science, Nanyang Technological University 639798 Singapore
| | - Brajesh Kumar Kaushik
- Department of Electronics and Communication Engineering, Indian Institute of Technology Roorkee India
| | - Ali Alzahrani
- Department of Computer Engineering, College of Computer Sciences and Information Technology, King Faisal University Saudi Arabia
| | - Fawnizu Azmadi Hussin
- Department of Electrical and Electronics Engineering, Universiti Teknologi Petronas Malaysia
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Shimada K, Inokuchi R, Ohigashi T, Iwagami M, Tanaka M, Gosho M, Tamiya N. Artificial intelligence-assisted interventions for perioperative anesthetic management: a systematic review and meta-analysis. BMC Anesthesiol 2024; 24:306. [PMID: 39232648 PMCID: PMC11373311 DOI: 10.1186/s12871-024-02699-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/25/2024] [Accepted: 08/26/2024] [Indexed: 09/06/2024] Open
Abstract
BACKGROUND Integration of artificial intelligence (AI) into medical practice has increased recently. Numerous AI models have been developed in the field of anesthesiology; however, their use in clinical settings remains limited. This study aimed to identify the gap between AI research and its implementation in anesthesiology via a systematic review of randomized controlled trials with meta-analysis (CRD42022353727). METHODS We searched the databases of Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica Database (Embase), Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), Institute of Electrical and Electronics Engineers Xplore (IEEE), and Google Scholar and retrieved randomized controlled trials comparing conventional and AI-assisted anesthetic management published between the date of inception of the database and August 31, 2023. RESULTS Eight randomized controlled trials were included in this systematic review (n = 568 patients), including 286 and 282 patients who underwent anesthetic management with and without AI-assisted interventions, respectively. AI-assisted interventions used in the studies included fuzzy logic control for gas concentrations (one study) and the Hypotension Prediction Index (seven studies; adding only one indicator). Seven studies had small sample sizes (n = 30 to 68, except for the largest), and meta-analysis including the study with the largest sample size (n = 213) showed no difference in a hypotension-related outcome (mean difference of the time-weighted average of the area under the threshold 0.22, 95% confidence interval -0.03 to 0.48, P = 0.215, I2 93.8%). CONCLUSIONS This systematic review and meta-analysis revealed that randomized controlled trials on AI-assisted interventions in anesthesiology are in their infancy, and approaches that take into account complex clinical practice should be investigated in the future. TRIAL REGISTRATION This study was registered with the International Prospective Register of Systematic Reviews (PROSPERO ID: CRD42022353727).
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Affiliation(s)
- Kensuke Shimada
- Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan
- Translational Research Promotion Center, Tsukuba Clinical Research & Development Organization, University of Tsukuba, Ibaraki, Japan
- Department of Anesthesiology, University of Tsukuba Hospital, Ibaraki, Japan
| | - Ryota Inokuchi
- Department of Health Services Research, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.
- Department of Emergency and Critical Care Medicine, The University of Tokyo Hospital, Tokyo, Japan.
- Department of Clinical Engineering, The University of Tokyo Hospital, Tokyo, Japan.
| | - Tomohiro Ohigashi
- Department of Information and Computer Technology, Faculty of Engineering, Tokyo University of Science, Tokyo, Japan
- Department of Biostatistics, Institute of Medicine, University of Tsukuba, Ibaraki, Japan
| | - Masao Iwagami
- Department of Health Services Research, Institute of Medicine, University of Tsukuba, Ibaraki, Japan
| | - Makoto Tanaka
- Department of Anesthesiology, Institute of Medicine, University of Tsukuba, Ibaraki, Japan
| | - Masahiko Gosho
- Department of Biostatistics, Institute of Medicine, University of Tsukuba, Ibaraki, Japan
| | - Nanako Tamiya
- Department of Health Services Research, Institute of Medicine, University of Tsukuba, Ibaraki, Japan
- Health Services Research and Development Center, University of Tsukuba, Ibaraki, Japan
- Center for Artificial Intelligence Research, University of Tsukuba, Ibaraki, Japan
- Cybermedicine Research Center, University of Tsukuba, Ibaraki, Japan
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Hurley NC, Gupta RK, Schroeder KM, Hess AS. Danger, Danger, Gaston Labat! Does zero-shot artificial intelligence correlate with anticoagulation guidelines recommendations for neuraxial anesthesia? Reg Anesth Pain Med 2024; 49:661-667. [PMID: 38253610 DOI: 10.1136/rapm-2023-104868] [Citation(s) in RCA: 2] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/17/2023] [Accepted: 09/18/2023] [Indexed: 01/24/2024]
Abstract
INTRODUCTION Artificial intelligence and large language models (LLMs) have emerged as potentially disruptive technologies in healthcare. In this study GPT-3.5, an accessible LLM, was assessed for its accuracy and reliability in performing guideline-based evaluation of neuraxial bleeding risk in hypothetical patients on anticoagulation medication. The study also explored the impact of structured prompt guidance on the LLM's performance. METHODS A dataset of 10 hypothetical patient stems and 26 anticoagulation profiles (260 unique combinations) was developed based on American Society of Regional Anesthesia and Pain Medicine guidelines. Five prompts were created for the LLM, ranging from minimal guidance to explicit instructions. The model's responses were compared with a "truth table" based on the guidelines. Performance metrics, including accuracy and area under the receiver operating curve (AUC), were used. RESULTS Baseline performance of GPT-3.5 was slightly above chance. With detailed prompts and explicit guidelines, performance improved significantly (AUC 0.70, 95% CI (0.64 to 0.77)). Performance varied among medication classes. DISCUSSION LLMs show potential for assisting in clinical decision making but rely on accurate and relevant prompts. Integration of LLMs should consider safety and privacy concerns. Further research is needed to optimize LLM performance and address complex scenarios. The tested LLM demonstrates potential in assessing neuraxial bleeding risk but relies on precise prompts. LLM integration should be approached cautiously, considering limitations. Future research should focus on optimization and understanding LLM capabilities and limitations in healthcare.
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Affiliation(s)
- Nathan C Hurley
- Department of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA
| | - Rajnish K Gupta
- Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
| | | | - Aaron S Hess
- Department of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA
- Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA
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Harfaoui W, Alilou M, El Adib AR, Zidouh S, Zentar A, Lekehal B, Belyamani L, Obtel M. Patient Safety in Anesthesiology: Progress, Challenges, and Prospects. Cureus 2024; 16:e69540. [PMID: 39416553 PMCID: PMC11482646 DOI: 10.7759/cureus.69540] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 09/16/2024] [Indexed: 10/19/2024] Open
Abstract
Anesthesiology is considered a complex medical specialty. Its history has been marked by radical advances and profound transformations, owing to technical and pharmacological developments and innovations in the field, enabling us over the years to improve patient outcomes and perform longer, more complex surgical procedures on more fragile patients. However, anesthesiology has never been safe and free of challenges. Despite the advances made, it still faces risks associated with the practice of anesthesia, for both patients and healthcare professionals, and with some of the specific challenges encountered in low and middle-income countries. In this context, certain actions and initiatives must be carried out collaboratively. In addition, recent technologies and innovations such as simulation, genomics, artificial intelligence, and robotics hold promise for further improving patient safety in anesthesiology and overcoming existing challenges, making it possible to offer safer, more effective, and personalized anesthesia. However, this requires rigorous monitoring of ethical aspects and the reliability of the studies to reap the full benefits of the new technology. This literature review presents the evolution of anesthesiology over time, its current challenges, and its promising future. It underlines the importance of the new technologies and the need to pursue efforts and strengthen research in anesthesiology to overcome the persistent challenges and benefit from the advantages of the latest technology to guarantee safe, high-quality anesthesia with universal access.
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Affiliation(s)
- Wafaa Harfaoui
- Epidemiology and Public Health, Laboratory of Community Health, Preventive Medicine and Hygiene, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
- Epidemiology and Public Health, Laboratory of Biostatistics, Clinical Research and Epidemiology, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
| | | | - Ahmed Rhassane El Adib
- Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakesh, MAR
- Mohamed VI Faculty of Medicine, Mohammed VI University of Health Sciences, Casablanca, MAR
| | - Saad Zidouh
- Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
- Emergency Unit, Mohammed V Military Hospital, Rabat, MAR
| | - Aziz Zentar
- Direction, Military Nursing School of Rabat, Rabat, MAR
- General Surgery, Mohammed V Military Hospital, Rabat, MAR
- Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
| | - Brahim Lekehal
- Vascular Surgery, Ibn Sina University Hospital Center, Rabat, MAR
- Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
| | - Lahcen Belyamani
- Mohammed VI Foundation of Health Sciences, Mohammed VI University, Rabat, MAR
- Royal Medical Clinic, Mohammed V Military Hospital, Rabat, MAR
- Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
| | - Majdouline Obtel
- Epidemiology and Public Health, Laboratory of Community Health, Preventive Medicine and Hygiene, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
- Epidemiology and Public Health, Laboratory of Biostatistics, Clinical Research and Epidemiology, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR
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Zatt FP, Rocha ADO, Anjos LMD, Caldas RA, Cardoso M, Rabelo GD. Artificial intelligence applications in dentistry: A bibliometric review with an emphasis on computational research trends within the field. J Am Dent Assoc 2024; 155:755-764.e5. [PMID: 39093229 DOI: 10.1016/j.adaj.2024.05.013] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/15/2024] [Revised: 05/28/2024] [Accepted: 05/31/2024] [Indexed: 08/04/2024]
Abstract
BACKGROUND The aim of this study was to understand the trends regarding the use of artificial intelligence in dentistry through a bibliometric review. TYPES OF STUDIES REVIEWED The authors performed a literature search on Web of Science. They collected the following data: articles-number and density of citations, year, key words, language, document type, study design, and theme (main objective, diagnostic method, and specialties); journals-impact factor; authors-country, continent, and institution. The authors used Visualization of Similarities Viewer software (Leiden University) to analyze the data and Spearman test for correlation analysis. RESULTS After selection, 1,478 articles were included. The number of citations ranged from 0 through 327. The articles were published from 1984 through 2024. Most articles were characterized as proof of concept (979). Definition and classification of structures and diseases was the most common theme (550 articles). There was an emphasis on radiology (333 articles) and radiographic-based diagnostic methods (715 articles). China was the country with the most articles (251), and Asia was the continent with the most articles (871). The Charité-University of Medicine Berlin was the institution with the most articles (42), and the author with the most articles was Schwendicke (53). PRACTICAL IMPLICATIONS Artificial intelligence is an important clinical tool to facilitate diagnosis and provide automation in various processes.
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Harris J, Matthews J. Artificial Intelligence: Predicting Perioperative Problems. Br J Hosp Med (Lond) 2024; 85:1-4. [PMID: 39212575 DOI: 10.12968/hmed.2024.0262] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 09/04/2024]
Abstract
The rapidly developing field of artificial intelligence (AI) may soon equip clinicians with algorithms that model and predict perioperative problems with extreme accuracy. Here, we outline emerging AI applications in preoperative risk stratification and intraoperative event prediction, where algorithm performance has been shown to outstrip commonly used conventional risk prediction tools. While offering an enticing view of a novel perioperative practice with superhuman foresight, AI's limited scope and lack of transparency remain key challenges for widespread adoption. As yet it is unclear whether machine learning alone can influence human clinical practice to exert real-world effects on patient outcomes.
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Affiliation(s)
- Joseph Harris
- Department of Anaesthesia, Royal London Hospital, London, UK
| | - James Matthews
- Department of Anaesthesia, Royal London Hospital, London, UK
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Mergler BD, Toles AO, Alexander A, Mosquera DC, Lane-Fall MB, Ejiogu NI. Racial and Ethnic Patient Care Disparities in Anesthesiology: History, Current State, and a Way Forward. Anesth Analg 2024; 139:420-431. [PMID: 38153872 DOI: 10.1213/ane.0000000000006716] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/30/2023]
Abstract
Disparities in patient care and outcomes are well-documented in medicine but have received comparatively less attention in anesthesiology. Those disparities linked to racial and ethnic identity are pervasive, with compelling evidence in operative anesthesiology, obstetric anesthesiology, pain medicine, and critical care. This narrative review presents an overview of disparities in perioperative patient care that is grounded in historical context followed by potential solutions for mitigating disparities and inequities.
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Affiliation(s)
- Blake D Mergler
- From the Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
| | - Allyn O Toles
- From the Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
| | - Anthony Alexander
- Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
| | - Diana C Mosquera
- Department of Anesthesiology, Albany Medical Center, Albany, New York
| | - Meghan B Lane-Fall
- From the Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
| | - Nwadiogo I Ejiogu
- From the Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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46
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Savage M, Spence A, Turbitt L. The educational impact of technology-enhanced learning in regional anaesthesia: a scoping review. Br J Anaesth 2024; 133:400-415. [PMID: 38824073 DOI: 10.1016/j.bja.2024.04.045] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/31/2023] [Revised: 04/16/2024] [Accepted: 04/19/2024] [Indexed: 06/03/2024] Open
Abstract
BACKGROUND Effective training in regional anaesthesia (RA) is paramount to ensuring widespread competence. Technology-based learning has assisted other specialties in achieving more rapid procedural skill acquisition. If applicable to RA, technology-enhanced training has the potential to provide an effective learning experience and to overcome barriers to RA training. We review the current evidence base for use of innovative technologies in assisting learning of RA. METHODS Using scoping review methodology, three databases (MEDLINE, Embase, and Web of Science) were searched, identifying 158 relevant citations. Citations were screened against defined eligibility criteria with 27 studies selected for inclusion. Data relating to study details, technological learning interventions, and impact on learner experience were extracted and analysed. RESULTS Seven different technologies were used to train learners in RA: artificial intelligence, immersive virtual reality, desktop virtual reality, needle guidance technology, robotics, augmented reality, and haptic feedback devices. Of 27 studies, 26 reported a positive impact of technology-enhanced RA training, with different technologies offering benefits for differing components of RA training. Artificial intelligence improved sonoanatomical knowledge and ultrasound skills for RA, whereas needle guidance technologies enhanced confidence and improved needling performance, particularly in novices. Immersive virtual reality allowed more rapid acquisition of needling skills, but its functionality was limited when combined with haptic feedback technology. User friendly technologies enhanced participant experience and improved confidence in RA; however, limitations in technology-assisted RA training restrict its widespread use. CONCLUSIONS Technology-enhanced RA training can provide a positive and effective learning experience, with potential to reduce the steep learning curve associated with gaining RA proficiency. A combined approach to RA education, using both technological and traditional approaches, should be maintained as no single method has been shown to provide comprehensive RA training.
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Affiliation(s)
- Mairead Savage
- Department of Anaesthesia, Belfast Health and Social Care Trust, Belfast, UK.
| | - Andrew Spence
- Department of Gastroenterology, Belfast Health and Social Care Trust, Belfast, UK; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
| | - Lloyd Turbitt
- Department of Anaesthesia, Belfast Health and Social Care Trust, Belfast, UK
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Han L, Char DS, Aghaeepour N. Artificial Intelligence in Perioperative Care: Opportunities and Challenges. Anesthesiology 2024; 141:379-387. [PMID: 38980160 PMCID: PMC11239120 DOI: 10.1097/aln.0000000000005013] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 07/10/2024]
Abstract
Artificial intelligence (AI) applications have great potential to enhance perioperative care. This paper explores promising areas for AI in anesthesiology; expertise, stakeholders, and infrastructure for development; and barriers and challenges to implementation.
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Affiliation(s)
- Lichy Han
- Department of Anesthesiology, Perioperative, and Pain Medicine, School of Medicine, Stanford University, Stanford, California
| | - Danton S Char
- Department of Anesthesiology, Perioperative, and Pain Medicine, School of Medicine, Stanford University, Stanford, California
| | - Nima Aghaeepour
- Department of Anesthesiology, Perioperative, and Pain Medicine, School of Medicine, Stanford University, Stanford, California
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48
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Bedia AS, Mulla SA, Patil A, Bedia SV, Ghadage M, Mali S. Attitudes and Perceptions of Dentists and Dental Residents Practicing in the Navi Mumbai Region Toward the Use of Artificial Intelligence in Dentistry: A Descriptive Survey. Cureus 2024; 16:e66836. [PMID: 39280475 PMCID: PMC11393789 DOI: 10.7759/cureus.66836] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 08/14/2024] [Indexed: 09/18/2024] Open
Abstract
Introduction Artificial intelligence (AI) has been gaining considerable attention in recent years within the healthcare field. It has established a presence in various aspects of health sciences, including accurate diagnosis and precise, streamlined treatment. This study aimed to assess the attitudes of dental residents and dentists in the Navi Mumbai region toward the use of AI in dentistry. Methods An online questionnaire-based survey was conducted, inviting 130 dental residents and dentists from the Navi Mumbai region. The collected data were compiled on a worksheet and subjected to descriptive statistical tests, which were expressed in numbers and frequencies. Results A total of 100 responses were received. Sixty-eight percent of individuals agreed that AI helps enhance diagnosis and treatment planning in the dental field. Sixty-five percent of the respondents stated that they are most likely to incorporate AI tools into their practice within the next five years. Conclusion From the present study, it can be inferred that AI is a promising and essential subsidiary tool in dentistry as well as in healthcare as a whole. However, major concerns such as extensive, in-depth training, data security, and cybercrime must be addressed before the full-scale incorporation of AI in the health sciences.
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Affiliation(s)
- Aarti S Bedia
- Oral Medicine and Radiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND
| | - Sayem A Mulla
- Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND
| | - Amit Patil
- Conservative Dentistry and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND
| | - Sumit V Bedia
- Prosthodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND
| | - Mahesh Ghadage
- Prosthodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND
| | - Sheetal Mali
- Conservative Dentistry and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND
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Akduman S, Yilmaz K. Examining the effectiveness of artificial intelligence applications in asthma and COPD outpatient support in terms of patient health and public cost: SWOT analysis. Medicine (Baltimore) 2024; 103:e38998. [PMID: 39029048 PMCID: PMC11398804 DOI: 10.1097/md.0000000000038998] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 07/21/2024] Open
Abstract
This research aimed to examine the effectiveness of artificial intelligence applications in asthma and chronic obstructive pulmonary disease (COPD) outpatient treatment support in terms of patient health and public costs. The data obtained in the research using semiotic analysis, content analysis and trend analysis methods were analyzed with strengths, weakness, opportunities, threats (SWOT) analysis. In this context, 18 studies related to asthma, COPD and artificial intelligence were evaluated. The strengths of artificial intelligence applications in asthma and COPD outpatient treatment stand out as early diagnosis, access to more patients and reduced costs. The points that stand out among the weaknesses are the acceptance and use of technology and vulnerabilities related to artificial intelligence. Opportunities arise in developing differential diagnoses of asthma and COPD and in examining prognoses for the diseases more effectively. Malicious use, commercial data leaks and data security issues stand out among the threats. Although artificial intelligence applications provide great convenience in the outpatient treatment process for asthma and COPD diseases, precautions must be taken on a global scale and with the participation of international organizations against weaknesses and threats. In addition, there is an urgent need for accreditation for the practices to be carried out in this regard.
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Affiliation(s)
- Seha Akduman
- Department of Pulmonary Diseases, Yeditepe University, Faculty of Medicine, Istanbul, Türkiye
| | - Kadir Yilmaz
- Istanbul Commerce University, Social Sciences Institute, Industrial Policies and Technology Management Program (DR), Istanbul, Türkiye
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50
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Song Z, Cai J, Zhou Y, Jiang Y, Huang S, Gu L, Tan J. Knowledge, Attitudes and Practices Among Anesthesia and Thoracic Surgery Medical Staff Toward Ai-PCA. J Multidiscip Healthc 2024; 17:3295-3304. [PMID: 39006875 PMCID: PMC11246636 DOI: 10.2147/jmdh.s468539] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/12/2024] [Accepted: 06/27/2024] [Indexed: 07/16/2024] Open
Abstract
Purpose Artificial intelligence (AI) is increasingly influencing various medical fields, including anesthesiology. The Introduction of artificial intelligent patient-controlled analgesia (Ai-PCA) has been seen as a significant advancement in pain management. However, the adoption and practical application of Ai-PCA by medical staff, particularly in anesthesia and thoracic surgery, have not been extensively studied. This study aimed to investigate the knowledge, attitudes and practices (KAP) among anesthesia and thoracic surgery medical staff toward artificial intelligent patient-controlled analgesia (Ai-PCA). Participants and Methods This web-based cross-sectional study was conducted between November 1, 2023 and November 15, 2023 at Jiangsu Cancer Hospital. A self-designed questionnaire was developed to collect demographic information of anesthesia and thoracic surgery medical staff, and to assess their knowledge, attitudes and practices toward Ai-PCA. Results A total of 519 valid questionnaires were collected. Among the participants, 278 (53.56%) were female, 497 (95.76%) were employed in the field of anesthesiology, and 188 (36.22%) had participated in Ai-PCA training. The mean knowledge, attitude, and practice scores were 7.8±1.75 (possible range: 0-10), 37.43±4.16 (possible range: 9-45), and 28.38±9.27 (possible range: 9-45), respectively. Conclusion The findings revealed that anesthesia and thoracic surgery medical staff have sufficient knowledge, active attitudes, but poor practices toward the Ai-PCA. Comprehensive training programs are needed to improve anesthesia and thoracic surgery medical staff's practices in this area.
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Affiliation(s)
- Zhenghuan Song
- Department of Anesthesiology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 21009, People’s Republic of China
| | - Jiaqin Cai
- Xuzhou Medical University, Xuzhou, 21009, People’s Republic of China
| | - Yihu Zhou
- Nanjing Medical University, Nanjing, 21009, People’s Republic of China
| | - Yueyi Jiang
- Nanjing Medical University, Nanjing, 21009, People’s Republic of China
| | - Shiyi Huang
- Xuzhou Medical University, Xuzhou, 21009, People’s Republic of China
| | - Lianbing Gu
- Department of Anesthesiology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 21009, People’s Republic of China
- Xuzhou Medical University, Xuzhou, 21009, People’s Republic of China
| | - Jing Tan
- Department of Anesthesiology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 21009, People’s Republic of China
- Xuzhou Medical University, Xuzhou, 21009, People’s Republic of China
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