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World J Surg Proced. Mar 28, 2016; 6(1): 1-7
Published online Mar 28, 2016. doi: 10.5412/wjsp.v6.i1.1
Review of intraoperative parathormone monitoring with the miami criterion: A 25-year experience
Tanaz M Vaghaiwalla, Zahra F Khan, John I Lew
Tanaz M Vaghaiwalla, Zahra F Khan, John I Lew, Division of Endocrine Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, United States
Author contributions: The conception and design was performed by Vaghaiwalla TM, Khan ZF and Lew JI; the data collection was performed by Vaghaiwalla TM and Lew JI; the analysis and interpretation was performed by Vaghaiwalla TM and Lew JI; the writing of article was performed by Vaghaiwalla TM, Khan ZF and Lew JI; the critical revision of article was performed by Vaghaiwalla TM, Khan ZF and Lew JI.
Conflict-of-interest statement: The authors have no conflicts of interest to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: John I Lew, MD, FACS, Associate Professor of Surgery, Chief, Division of Endocrine Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, 1120 NW 14th St, 4th Floor, Clinical Research Building 410P, Miami, FL 33136, United States. jlew@med.miami.edu
Telephone: +1-305-2434211 Fax: +1-305-2434221
Received: August 29, 2015
Peer-review started: September 6, 2015
First decision: October 30, 2015
Revised: December 3, 2015
Accepted: December 29, 2015
Article in press: January 4, 2016
Published online: March 28, 2016
Processing time: 209 Days and 8.3 Hours
Core Tip

Core tip: Intraoperative parathormone monitoring (IPM) is vital component of the focused parathyroidectomy, the management of choice for primary hyperparathyroidism at the authors’ institution. IPM is used to confirm complete removal of hyperfunctioning glands while preserving any remaining normally functioning glands before the operation is finished, guide the surgeon to continue neck exploration for additional hyperfunctioning glands when the intraoperative parathormone (PTH) levels do not drop sufficiently, identify parathyroid tissue by measurement of intraoperative PTH levels in fine needle aspiration samples, and lateralize hypersecreting parathyroid(s) through differential jugular venous sampling when preoperative localization studies are equivocal.