©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Surg Proced. Mar 28, 2015; 5(1): 14-26
Published online Mar 28, 2015. doi: 10.5412/wjsp.v5.i1.14
Published online Mar 28, 2015. doi: 10.5412/wjsp.v5.i1.14
Techniques that accurately identify the sentinel lymph node in cancer
Kelly J Rosso, S David Nathanson, Department of Surgery, Wayne State Medical School at Henry Ford Health System, Detroit, MI 48202, United States
Author contributions: Both authors contributed to this manuscript.
Conflict-of-interest: The authors have no conflicts of interest to disclose.
Correspondence to: S David Nathanson, MD, Department of Surgery, Wayne State Medical School at Henry Ford Health System, 2799 West Grand Blvd, Detroit, MI 48202, United States. dnathan1@hfhs.org
Telephone: +1-800-4367936
Received: September 29, 2014
Peer-review started: September 29, 2014
First decision: December 12, 2014
Revised: January 19, 2015
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: March 28, 2015
Processing time: 185 Days and 12.4 Hours
Peer-review started: September 29, 2014
First decision: December 12, 2014
Revised: January 19, 2015
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: March 28, 2015
Processing time: 185 Days and 12.4 Hours
Core Tip
Core tip: Novel localization techniques including near infrared fluorescence, high resolution imaging and molecular targeted agents have been developed to address the limitations of conventional sentinel lymph node (SLN) detection practices in many solid tumor types. This article reviews the indications, techniques and detection rates for SLN biopsy in several different solid tumor types as well as the promising novel techniques created to address the contemporary limitations of this procedure.