Garg PK, Chowdhury S, Seenivasagam RK, Poonia DR. Regional lymphadenectomy in advanced ovarian cancer: The enigma continues. World J Surg Proced 2020; 10(1): 1-2 [DOI: 10.5412/wjsp.v10.i1.1]
Corresponding Author of This Article
Pankaj Kumar Garg, MS, DNB, MCh, FACS, Additional Professor, Department of Surgical Oncology, All India Institute of Medical Sciences, Veerbhadra Marg, Rishikesh, Uttarakhand 249203, India. dr.pankajgarg@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Letter To The Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Pankaj Kumar Garg, Rajkumar K Seenivasagam, Dharma Ram Poonia, Department of Surgical Oncology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203, India
Sandipan Chowdhury, Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203, India
Author contributions: Garg PK wrote the initial draft; all the authors read the final draft and approved it.
Conflict-of-interest statement: The authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Pankaj Kumar Garg, MS, DNB, MCh, FACS, Additional Professor, Department of Surgical Oncology, All India Institute of Medical Sciences, Veerbhadra Marg, Rishikesh, Uttarakhand 249203, India. dr.pankajgarg@gmail.com
Received: July 11, 2019 Peer-review started: July 17, 2019 First decision: November 12, 2019 Revised: November 19, 2019 Accepted: December 23, 2019 Article in press: December 23, 2019 Published online: January 3, 2020 Processing time: 170 Days and 8.3 Hours
Abstract
The role of regional lymphadenectomy has always been a matter of discussion in the surgical management of solid tumors – Pelvic and para-aortic lymphadenectomy in ovarian cancer is one such issue. A recently published randomized trial suggested that regional lymphadenectomy in patients with advanced ovarian cancer is unlikely to offer a survival advantage. However, para-aortic and pelvic lymphadenectomy is warranted in the presence of macroscopically suspicious nodes to achieve complete cytoreduction. A long-term follow-up of the trial will demonstrate whether a prophylactic regional lymphadenectomy is associated with survival benefit in a subgroup of patients with advanced ovarian cancer who have grossly normal regional lymphnodes as evident in a widely open retroperitoneum.
Core tip: Para-aortic and pelvic lymphadenectomy is warranted in macroscopically suspicious nodes in patients with advanced ovarian cancer to achieve complete cytoreduction.
