Preclinical pharmacology studies of zingerone with special reference to potential therapeutic applications

Table 1 Zingerone possessing various pharmacological activities

No.	Activities	Doses	Route	Animals	Treatment duration	Ref.
1	Antioxidant	20 mg/kg	Oral	Rats	30 days	[20]
2	Anti-inflammatory	100 mg/kg	Oral	Mice	4 hours	[24]
3	Anti-cancer	10 mg/kg	Intraperitoneal	Mice	14 days	[8]
4	Radioprotective	20 mg/kg	Oral	Mice	5 days	[37]
5	Nephroprotective	50 mg/kg	Ora	Rats	7 days	[44]
6	Hepatoprotective	20 mg/kg	Oral	Rats	30 days	[52]
7	Cardioprotective	6 mg/kg	Oral	Rats	14 days	[60]
8	Neuroprotective	100 mg/kg	Oral	Rats	24 hours	[67]
9	Anti-diarrheal	10 mg/kg	Intraluminal	Rats	-	[71]
10	Anti-microbial	1 mg/mL	In-vitro			[76]
11	Anti-diabetic	100 mg/kg	Oral	Rats	21 days	[80]
12	Gonad-protective	40 mg/kg and 50 mg/kg	Oral	Male mice and female rats	35 days and 7 days	[84]
13	Ant-arthritic activity	25 mg/kg	Oral	Rats	21 days	[87]