©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Review of immunological responses to porcine coronaviruses and implications on population based control strategies in epidemic and endemic infections
Elsa Kanner-Acerbo, James Lowe, Integrated Food Animal Medicine Systems, Department of Veterinary Clinical Medicine, University of Illinois, Urbana, IL 61802, United States
Author contributions: Kanner-Acerbo E and Lowe J contributed equally to this paper.
Conflict-of-interest statement: The authors report no conflicts of interest.
Correspondence to: James Lowe, DVM, MS, DABVP, Associate Professor and Director, Integrated Food Animal Medicine Systems, Department of Veterinary Clinical Medicine, University of Illinois, 230 LAC, 1008 W, Hazelwood Dr, Urbana, IL 61802, United States. jlowe@illinois.edu
Telephone: +1-217-3006398 Fax: +1-217-3334628
Received: June 27, 2015
Peer-review started: June 29, 2015
First decision: August 16, 2015
Revised: February 22, 2016
Accepted: March 14, 2016
Article in press: March 26, 2016
Published online: March 27, 2016
Processing time: 274 Days and 11 Hours
Peer-review started: June 29, 2015
First decision: August 16, 2015
Revised: February 22, 2016
Accepted: March 14, 2016
Article in press: March 26, 2016
Published online: March 27, 2016
Processing time: 274 Days and 11 Hours
Core Tip
Core tip: Coronaviruses (COVs) cause severe disease in both pigs and humans. New immunological research in pigs has revealed many similarities between porcine and human responses to COVs. Understanding the immunological responses of pigs to COVs may prove that they are a viable human model to study these diseases, as well as providing new and more efficacious control mechanisms for veterinarians and swine producers worldwide.