Modality matters: Effect of dialysis modality on soluble intercellular adhesion molecule-1 in children on regular hemodialysis

doi:10.5409/wjcp.120090

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 3

This Article

(1)

(5)

(0)

(20)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Clinical Pediatrics

ISSN

2219-2808

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Sep 9, 2026; 15(3): 120090
Published online Sep 9, 2026. doi: 10.5409/wjcp.120090

Table 1 Values of serum intercellular adhesion molecule-1 levels

Parameters	HD modality	Cases		Controls		P value	Mean difference (95%CI)
Parameters	HD modality	mean ± SD	Median (IQR)	mean ± SD	Median (IQR)	P value	Mean difference (95%CI)
Pre-session ICAM-1 (ng/L)	LFHD	1174.48 ± 1221.36	676.55 (493.88-1426.00)	174.61 ± 55.50	171.15 (125.23-226.98)	< 0.001¹	523.6³ (391.0-784.2)
	HFHD	1665.82 ± 1566.27	1080.00 (785.75-2009.50)			< 0.001¹	929.6³ (691.2-1496.4)
	OL-HDF	1493.76 ± 863.61	1207.00 (640.05-2529.00)			< 0.001¹	1045.7³ (593.0-1998.1)
Post-session cICAM-1 (ng/L)	LFHD	2217.18 ± 1675.90	1481.50 (1147.30-2993.10)			< 0.001¹	1312.6³ (1056.8-2133.2)
	HFHD	316.51 ± 262.17	240.97 (148.91-390.61)			0.026¹	62.2³ (6.9-144.4)
	OL-HDF	172.24 ± 74.83	163.63 (121.93-204.36)			0.890²	-2.4⁴ (-39.3-34.6)

¹Mann-Whitney test.

²Student t test.

³Hodges-Lehman median difference estimate.

⁴Mean difference.

ICAM-1: Intercellular adhesion molecule-1; cICAM-1: Corrected intercellular adhesion molecule-1; HD: Hemodialysis; LFHD: Low flux hemodialysis; HFHD: High flux hemodialysis; OL-HDF: Online hemodiafiltration; IQR: Interquartile range; CI: Confidence interval.

Full Size Table

Table 2 Comparisons of serum intercellular adhesion molecule-1 levels

Cases		P value	Mean difference (95%CI)
Pre-session sICAM-1	LFHD vs HFHD	0.058¹	378.9² (-10.1-864.6)
	LFHD vs OL-HDF	0.051¹	737.7² (100.9-1449.0)
	HFHD vs OL-HDF	0.751¹	13.3² (-364.2-812.4)
Post-session cICAM-1	LFHD vs HFHD	< 0.001¹	-1655.6² (-2633.7 to -1088.0)
	LFHD vs OL-HDF	< 0.001¹	-1727.2² (-2782.8 to -1188.8)
	HFHD vs OL-HDF	0.011¹	-84.1² (-173.7 to -25.3)
Pre-session vs post-session cICAM-1	LFHD	0.002¹	871.5² (373.2-1749.9)
	HFHD	< 0.001¹	-1087.1² (-1439.5 to -755.6)
	OL-HDF	< 0.001¹	-1372.9² (-2143.8 to -786.9)

¹Wilcoxon signed ranks test.

²Hodges-Lehman median difference estimate.

sICAM-1: Soluble intercellular adhesion molecule-1; cICAM-1: Corrected intercellular adhesion molecule-1; LFHD: Low flux hemodialysis; HFHD: High flux hemodialysis; OL-HDF: Online hemodiafiltration; CI: Confidence interval.

Full Size Table

Citation: Kasem MF, Said RM, Dahshan DR, Elhadedy SH, Mohammed NR, Hashem NU. Modality matters: Effect of dialysis modality on soluble intercellular adhesion molecule-1 in children on regular hemodialysis. World J Clin Pediatr 2026; 15(3): 120090
URL: https://www.wjgnet.com/2219-2808/full/v15/i3/120090.htm
DOI: https://dx.doi.org/10.5409/wjcp.120090

Kasem MF, Said RM, Dahshan DR, Elhadedy SH, Mohammed NR, Hashem NU. Modality matters: Effect of dialysis modality on soluble intercellular adhesion molecule-1 in children on regular hemodialysis. World J Clin Pediatr 2026; 15(3): 120090 [DOI: 10.5409/wjcp.120090]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.