©Author(s) (or their employer(s)) 2026.
World J Clin Pediatr. Mar 9, 2026; 15(1): 111388
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.111388
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.111388
Table 1 Demographic and clinical characteristics of participants, n (%)
| Variable | Category | Experimental group (n = 300) | Control group (n = 300) | χ2 | P value |
| Age (years) | 3, 4 | 135 (45.0) | 106 (35.3) | 6.72 | 0.034 |
| 4, 5 | 68 (22.7) | 90 (30.0) | |||
| 5, 6 | 97 (32.3) | 104 (34.7) | |||
| Gender | Male | 187 (62.3) | 200 (66.7) | 0.81 | 0.369 |
| Female | 113 (37.7) | 100 (33.3) | |||
| Residence | Rural | 164 (54.7) | 192 (64.0) | 4.58 | 0.032 |
| Urban | 136 (45.3) | 108 (36.0) | |||
| IV site | Cephalic vein | 5 (1.7) | 21 (7.0) | 12.45 | 0.002 |
| Metacarpal vein | 259 (86.3) | 266 (88.7) | |||
| Median vein | 36 (12.0) | 13 (4.3) | |||
| IV cannula size | 22 G | 63 (21.0) | 98 (32.7) | 7.88 | 0.005 |
| 24 G | 237 (79.0) | 202 (67.3) |
Table 2 Post-test pain levels (Wong-Baker FACES Pain Rating Scale) by group, n (%)
| Pain level (Wong-Baker FACES Pain Rating Scale) | Experimental group (n = 300) | Control group (n = 300) | P value |
| No hurt (0) | 20 (6.67) | 0 (0.00) | < 0.001 |
| Hurts little bit (1) | 114 (38.00) | 0 (0.00) | |
| Hurts little more (2) | 151 (50.33) | 0 (0.00) | |
| Hurts even more (3) | 15 (5.00) | 0 (0.00) | |
| Hurts whole lot (4) | 0 (0.00) | 167 (55.66) | |
| Hurts worst (5) | 0 (0.00) | 133 (44.33) |
Table 3 Predictors of severe pain
| Variable | Category | B | SE | Odds ratio (95%CI) | P value |
| Group | Control vs experimental | 5.98 | 0.58 | 396.4 (125.9-1247.7) | < 0.001 |
| Age (years) | 3, 4 (refence: 5, 6) | 0.64 | 0.28 | 1.89 (1.10-3.25) | 0.021 |
| Gender | Male vs female | 0.29 | 0.26 | 1.34 (0.80-2.23) | 0.263 |
| Residence | Rural vs urban | 0.41 | 0.25 | 1.51 (0.93-2.45) | 0.098 |
| Intravenous site | Cephalic vs metacarpal | 1.88 | 0.58 | 6.54 (2.08-20.54) | 0.001 |
| Median vs metacarpal) | 0.72 | 0.35 | 2.06 (1.05-4.06) | 0.036 | |
| Cannula size | 22 G vs 24 G | 0.86 | 0.26 | 2.36 (1.39-4.02) | 0.002 |
Table 4 Comparison of post-test pain scores
| Group | Mean (Wong-Baker FACES Pain Rating Scale) | SD | Mean difference | t value | P value |
| Experimental (n = 300) | 3.07 | 1.390 | 5.73 | 58.56 | < 0.001 |
| Control (n = 300) | 8.80 | 1.007 |
Table 5 Predictors of high anxiety
| Variable | Category | B | SE | Odds ratio (95%CI) | P value |
| Group | Control vs experimental) | 4.86 | 0.55 | 129.2 (44.7-373.6) | < 0.001 |
| Age (years) | 3, 4 (refence: 5, 6) | 0.72 | 0.30 | 2.06 (1.14-3.72) | 0.017 |
| Gender | Male vs female | 0.33 | 0.27 | 1.39 (0.81-2.39) | 0.232 |
| Residence | Rural vs urban | 0.48 | 0.26 | 1.62 (0.97-2.71) | 0.066 |
| Intravenous site | Cephalic vs metacarpal | 1.55 | 0.53 | 4.72 (1.66-13.42) | 0.004 |
| Median vs metacarpal | 0.61 | 0.32 | 1.84 (0.98-3.43) | 0.057 | |
| Cannula size | 22 G vs 24 G | 0.91 | 0.27 | 2.48 (1.46-4.21) | 0.001 |
Table 6 Comparison of post-test anxiety scores
| Group | Mean (Visual Analogue Anxiety Scale) | SD | Mean difference | t value | P value |
| Experimental (n = 300) | 5.85 | 1.560 | 3.54 | 35.55 | < 0.00001 |
| Control (n = 300) | 9.39 | 0.730 |
Table 7 Correlation between pain and anxiety scores by group
| Group | Pain, mean (SD) | Anxiety, mean (SD) | r value | P value |
| Experimental (n = 300) | 3.07 (1.39) | 5.85 (1.56) | 0.67 | < 0.05 |
| Control (n = 300) | 8.80 (1.01) | 9.39 (0.73) | 0.66 | < 0.05 |
- Citation: Wilson LP, Khan Z, Patil PN, Konnur RG, Sriram N. Multimodal distraction reduces intravenous cannulation pain and anxiety in preschoolers: Controlled prospective study. World J Clin Pediatr 2026; 15(1): 111388
- URL: https://www.wjgnet.com/2219-2808/full/v15/i1/111388.htm
- DOI: https://dx.doi.org/10.5409/wjcp.v15.i1.111388
