Revisiting modifiable determinants of bronchopulmonary dysplasia in very preterm infants

doi:10.5409/wjcp.120197

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Pediatr. Sep 9, 2026; 15(3): 120197
Published online Sep 9, 2026. doi: 10.5409/wjcp.120197

Revisiting modifiable determinants of bronchopulmonary dysplasia in very preterm infants

Pushparaj Nilkanth Patil

Pushparaj Nilkanth Patil, Department of Pediatrics, NAMO Medical Education and Research Institute, Silvassa 396230, Dādra and Nagar Haveli and Damān and Diu, India

Author contributions: Patil PN conceptualized and designed the study, performed the literature review, conducted data analysis and interpretation, drafted the manuscript, and approved the final version for submission

Conflict-of-interest statement: The author declares that there are no conflicts of interest related to this manuscript.

Corresponding author: Pushparaj Nilkanth Patil, MD, Associate Professor, Department of Pediatrics, NAMO Medical Education and Research Institute, Sayali Road, Silvassa 396230, Dādra and Nagar Haveli and Damān and Diu, India. piyush.patil05@gmail.com

Received: February 24, 2026
Revised: March 30, 2026
Accepted: April 15, 2026
Published online: September 9, 2026
Processing time: 165 Days and 11.9 Hours

Core Tip

Core Tip: The study by Algharabeh et al suggests that bronchopulmonary dysplasia in preterm infants remains strongly associated with modifiable exposures, including prolonged mechanical ventilation, oxygen toxicity, and sepsis. Significant maternal interactions are also found in the present study, which includes associations between preeclampsia and patent ductus arteriosus, and between multiple gestation and late-onset sepsis. These findings highlight the importance of respiratory care, infection control, and appropriate prenatal care to reduce lung injury and improve long-term respiratory outcomes.