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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Pediatr. Sep 9, 2026; 15(3): 118387
Published online Sep 9, 2026. doi: 10.5409/wjcp.118387
Neonatal varicella zoster transmission from mother, management in a resource-limited setting: A case report
Kamil Ahmad Kamil, Sadaf Naz, Humaira, Zainab Khattak, Ali Dad, Inayat Ullah, Hakim Ullah Wazir
Hakim Ullah Wazir, Department of Medicine, Lady Reading Hospital, Peshawar 25000, Khyber Pakhtunkhwa, Pakistan
Inayat Ullah, Department of Pediatrics, Gujju Khan Medical College, Swabi 35100, Khyber Pakhtunkhwa, Pakistan
Ali Dad, Zainab Khattak, Humaira, Sadaf Naz, Department of Medicine, Gujju Khan Medical College, Swabi 35100, Khyber Pakhtunkhwa, Pakistan
Kamil Ahmad Kamil, Department of Internal Medicine, Mirwais Regional Hospital, Kandahar 3801, Kandahār, Afghanistan
Kamil Ahmad Kamil, Medical Faculty, Malalay Institute of Higher Education, Kandahar 3802, Kandahār, Afghanistan
Author contributions: Wazir HU contributed to conceptualization, investigation, writing – original draft, preparation; Ullah I contributed to supervision; Hateef AD contributed to formal analysis, data collection; Humaira contributed to visualization, project administration; Kamil KA contributed to corresponding author responsibilities; Wazir HU and Naz S contributed to data curation; Ullah I, Khattak Z, and Kamil KA contributed to writing – review & editing; Ullah I and Naz S contributed to resources; Khattak Z and Kamil KA contributed to validation.
AI contribution statement: AI-based tools (e.g., ChatGPT and/or Grammarly) were used to assist with minor language refinement and to improve clarity and readability.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Kamil Ahmad Kamil, MD, Chief Physician, Consultant, Department of Internal Medicine, Mirwais Regional Hospital, Shahre-Naw, Kandahar 3801, Kandahār, Afghanistan. drkamilahmad1@gmail.com
Received: December 31, 2025
Revised: January 27, 2026
Accepted: March 9, 2026
Published online: September 9, 2026
Processing time: 213 Days and 9.9 Hours
Core Tip

Core Tip: This case report highlights the critical management of neonatal varicella in a resource-limited setting where standard interventions like varicella-zoster immunoglobulin and polymerase chain reaction testing are unavailable. It demonstrates that a timely clinical diagnosis based on characteristic rash and maternal history, coupled with prompt intravenous acyclovir therapy and meticulous supportive care, can lead to a favourable outcome. The case underscores the importance of clinical acumen and accessible antiviral treatment as effective alternatives for managing this life-threatening condition when advanced resources are constrained.

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