Systematic Reviews
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Jun 9, 2025; 14(2): 102002
Published online Jun 9, 2025. doi: 10.5409/wjcp.v14.i2.102002
Importance of celiac disease oral manifestations in pediatric patients: A systematic review
Viviana Macho, Rita Rodrigues, Diana Pinto, Rita Castro, Cátia Carvalho Silva, Cristina Cardoso Silva, Sandra Clara Soares
Viviana Macho, Rita Rodrigues, Diana Pinto, Rita Castro, Cátia Carvalho Silva, Cristina Cardoso Silva, Sandra Clara Soares, Faculty of Health Sciences, University Fernando Pessoa, Porto 4249-004, Portugal
Co-first authors: Viviana Macho and Rita Rodrigues.
Author contributions: Macho V, Pinto D, Rodrigues R designed the overall concept and outline of the manuscript; Macho V, Pinto D, Rodrigues R, Soares CC contributed to the discussion and design of the manuscript; Castro R, Silva CC, contributed to the writing, and editing the manuscript and review of literature; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: No financial or non-financial benefits have been received or will be received from any party related directly or indirectly to the subject of this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sandra Clara Soares, PhD, Assistant Professor, Doctor, Faculty of Health Sciences, University Fernando Pessoa, Praça de 9 de Abril 349, Porto 4249-004, Portugal. vmacho@ufp.edu.pt
Received: October 5, 2024
Revised: February 6, 2025
Accepted: February 20, 2025
Published online: June 9, 2025
Processing time: 163 Days and 17.3 Hours
Core Tip

Core Tip: Celiac disease is a chronic enteropathy with atypical manifestations and complex etiopathogenesis, challenging clinicians. Understanding its oral manifestations can greatly improve patients' quality of life. These manifestations occur in the non-keratinized oral mucosa, impacting feeding, speech, swallowing, and tooth brushing. Dentists play a crucial role in treating oral consequences, identifying cases early, and referring patients for medical evaluation. Their involvement is essential for timely diagnosis and management. Multidisciplinary collaboration between dentists and physicians ensures comprehensive care, addressing both oral and gastrointestinal aspects. Early detection and intervention can significantly improve outcomes and prevent long-term complications for affected individuals.