Sorokina L, Kaneva M, Artamonov A, Gordeeva N, Chikova I, Kostik M. Clinical and laboratory features of juvenile idiopathic arthritis with wrist involvement: Results of a retrospective cohort study. World J Clin Pediatr 2024; 13(3): 91656 [PMID: 39350901 DOI: 10.5409/wjcp.v13.i3.91656]
Corresponding Author of This Article
Mikhail Kostik, MD, PhD, Professor, Hospital Pediatry, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint-Petersburg 194100, Russia. kost-mikhail@yandex.ru
Research Domain of This Article
Rheumatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Lyubov Sorokina, Maria Kaneva, Artem Artamonov, Irina Chikova, Mikhail Kostik, Hospital Pediatry, Saint Petersburg State Pediatric Medical University, Saint Petersburg 194100, Russia
Natalia Gordeeva, Department of Consulting and Diagnostic, Saint-Petersburg Children’s Hospital #2, n.a. Saint Mary Magdalene, Saint Petersburg 199004, Russia
Mikhail Kostik, Research Laboratory of Autoimmune and Autoinflammatory Diseases, Almazov National Medical Research Center, Saint-Petersburg 197341, Russia
Author contributions: Kostik MM and Sorokina LS contributed to conceptualization, writing—review and editing; Kostik MM and Chikova IA contributed to methodology; Artamonov AK contributed to software, resources, and data curation; Artamonov AK, Kaneva MA, and Gordeeva NA contributed to validation; Sorokina LS contributed to formal analysis; Kaneva MA contributed to investigation and visualization; Kostik MM contributed to writing—original draft preparation, funding, supervision, and project administration; All authors have read and agreed to the published version of the manuscript.
Supported byMinistry of Science and Higher Education of the Russian Federation, No. 075-15-2022-301.
Institutional review board statement: The protocol of the study was approved by the local Ethical Committee of Saint Petersburg State Pediatric Medical University (#11/10 from 23.11.2020).
Informed consent statement: Informed consent was obtained from all subjects involved in the study.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—a checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mikhail Kostik, MD, PhD, Professor, Hospital Pediatry, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint-Petersburg 194100, Russia. kost-mikhail@yandex.ru
Received: January 1, 2024 Revised: June 16, 2024 Accepted: June 26, 2024 Published online: September 9, 2024 Processing time: 241 Days and 11.1 Hours
Core Tip
Core Tip: Wrist arthritis has specific symptoms, such as muscle weakness, paresthesia, limited fist function, limited pinch grip, joint deviation, aesthetic complaints, and difficulties in writing, drawing, and working with a knife, pencil, laptop, or other device. The frequency of wrist involvement in juvenile idiopathic arthritis categories was 5.8% in oligoarthritis, 44.9% in RF(−), 15.0% in RF( +) polyarthritis, 17.7% in enthesytis-related arthritis, and 58.6% in systemic. Wrist arthritis was associated with higher inflammation, specific joint involvement (cervical spine, temporomandibular, shoulder, elbow, metacarpophalangeal, proximal interphalangeal, distal interphalangeal, hip, ankle, and tarsus), a lower probability of achieving remission, and a higher probability of being treated with biologics.
