Indrawan M, Chendana J, Handoko TGH, Widjaja M, Octavius GS. Clinical factors predicting rotavirus diarrhea in children: A cross-sectional study from two hospitals. World J Clin Pediatr 2023; 12(5): 319-330 [PMID: 38178938 DOI: 10.5409/wjcp.v12.i5.319]
Corresponding Author of This Article
Gilbert Sterling Octavius, MD, MM, Doctor, Researcher, Department of Pediatric, Universitas Pelita Harapan, Jl. Jend. Sudirman No. 20 Bencongan, Kec. Klp. Dua, Kabupaten Tangerang, Banten 15811, Indonesia. sterlinggilbert613@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Dec 9, 2023; 12(5): 319-330 Published online Dec 9, 2023. doi: 10.5409/wjcp.v12.i5.319
Clinical factors predicting rotavirus diarrhea in children: A cross-sectional study from two hospitals
Michelle Indrawan, Jason Chendana, Tan Gabriella Heidina Handoko, Melanie Widjaja, Gilbert Sterling Octavius
Michelle Indrawan, Jason Chendana, Tan Gabriella Heidina Handoko, Melanie Widjaja, Gilbert Sterling Octavius, Department of Pediatric, Universitas Pelita Harapan, Banten 15811, Indonesia
Author contributions: Octavius GS and Widjaja M designed the research study; Indrawan M, Chendana J, Handoko TGH, and Octavius GS performed the research; Indrawan M and Chendana J gathered and analyzed the data; Indrawan M, Chendana J, Octavius GS, and Handoko TGH wrote the draft; All authors have read, edited and approved the final manuscript.
Institutional review board statement: This study protocol was approved by the Committee on Ethics at the University of Pelita Harapan, Tangerang, Indonesia, with Code Ethic No. 430/FK-UPH/Ext./V/2019.
Informed consent statement: The ethical board exempted informed consent due to the retrospective nature of our study. Identities were removed entirely, and data were analysed anonymously.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Data sharing statement: Data is available upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gilbert Sterling Octavius, MD, MM, Doctor, Researcher, Department of Pediatric, Universitas Pelita Harapan, Jl. Jend. Sudirman No. 20 Bencongan, Kec. Klp. Dua, Kabupaten Tangerang, Banten 15811, Indonesia. sterlinggilbert613@hotmail.com
Received: July 19, 2023 Peer-review started: July 19, 2023 First decision: August 31, 2023 Revised: September 7, 2023 Accepted: September 25, 2023 Article in press: September 25, 2023 Published online: December 9, 2023 Processing time: 141 Days and 12.9 Hours
Core Tip
Core Tip: Rotavirus gastroenteritis accounted for 19.11% of diarrheal deaths worldwide in 2019 and is still a leading cause of morbidity and mortality, especially in children under five. This cross-sectional study involving 267 children found that wet season (ORadj = 2.5; 95%CI: 1.3-4.8, Padj = 0.006), length of stay ≥ 3 d (ORadj = 5.1; 95%CI: 1.4-4.8, Padj = 0.015), presence of abdominal pain (ORadj = 3.0; 95%CI: 1.3-6.8, Padj = 0.007), severe dehydration (ORadj = 2.9; 95%CI: 1.1-7.9, Padj = 0.034), abnormal white blood cell counts (ORadj = 2.8; 95%CI: 1.3-6.0, Padj = 0.006), abnormal random blood glucose (ORadj = 2.3; 95%CI: 1.2-4.4, Padj = 0.018) and presence of fecal leukocytes (ORadj = 4.1, 95%CI: 1.7-9.5, Padj = 0.001) are predictors of rotavirus diarrhea.
