Bhatt MC, Singhal M, Pilania RK, Bansal SC, Khandelwal N, Gupta P, Singh S. Radiation dose analysis of computed tomography coronary angiography in Children with Kawasaki disease. World J Clin Pediatr 2023; 12(4): 230-236 [PMID: 37753492 DOI: 10.5409/wjcp.v12.i4.230]
Corresponding Author of This Article
Manphool Singhal, MD, DNB, FICR, FSCCT, FSCMR, Professor, Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Madhya Marg, Sector 12, Chandigarh 160012, India. drmsinghal74@gmail.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Bhatt MC, Singhal M, Pilania RK, Bansal SC, Khandelwal N, Gupta P, Singh S. Radiation dose analysis of computed tomography coronary angiography in Children with Kawasaki disease. World J Clin Pediatr 2023; 12(4): 230-236 [PMID: 37753492 DOI: 10.5409/wjcp.v12.i4.230]
Mahesh Chandra Bhatt, Manphool Singhal, Subhash Chand Bansal, Niranjan Khandelwal, Pankaj Gupta, Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Rakesh Kumar Pilania, Surjit Singh, Pediatric Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
Author contributions: Bhatt MC and Singhal M contributed to the data interpretation, writing of first draft, review of literature, editing of manuscript and critical revision of manuscript at all stages; Pilania RK contributed to the patient management, data interpretation, writing of first draft, review of literature, editing of manuscript and critical revision of manuscript at all stages; Bansal SC, Khandelwal N, and Gupta P contributed to the review of literature and editing of manuscript; Singh S contributed to the patient management, review of literature, editing of manuscript, critical revision of manuscript at all stages; Bhatt MC and Singhal M contributed equally; Singhal M finally approved the manuscript.
Institutional review board statement: The manuscript has been approved by Departmental Publication Review Board (RDG/EC/Pub/27 dated July 03, 2020), No. NK/1837/Res/2890.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The author(s) declare(s) that they had full access to all of the data in this study and the author(s) take(s) complete responsibility for the integrity of the data and the accuracy of the data analysis.
Corresponding author: Manphool Singhal, MD, DNB, FICR, FSCCT, FSCMR, Professor, Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Madhya Marg, Sector 12, Chandigarh 160012, India. drmsinghal74@gmail.com
Received: May 17, 2023 Peer-review started: May 17, 2023 First decision: July 4, 2023 Revised: July 12, 2023 Accepted: August 9, 2023 Article in press: August 9, 2023 Published online: September 9, 2023 Processing time: 111 Days and 15.6 Hours
ARTICLE HIGHLIGHTS
Research background
There is evolving role of computed tomography coronary angiography (CTCA) in non-invasive evaluation of coronary artery abnormalities in children with Kawasaki disease (KD). Despite this, there is lack of data on radiation dose in this group of children undergoing CTCA.
Research motivation
There is paucity of literature on radiation exposure in children with KD undergoing CTCA for coronary artery assessment.
Research objectives
To estimate the radiation dose exposure in children with KD undergoing CTCA for coronary artery assessment.
Research methods
Children with KD who underwent CTCA were either at presentation or on regular follow were included in the analysis. System generated radiation exposure dose length product (DLP in milligray-centimeters-mGy.cm) was recorded and effective radiation dose (millisieverts-mSv) was calculated by applying age adjusted conversion factors.
Research results
Total 85 children with median age of 5 years were scanned. Mean effective radiation dose was 0.83 mSv with radiation exposure significantly lower in infants (0.63 mSv) as compared to other age groups. CTCA demonstrated coronary artery abnormalities along the entire course of coronary arteries.
Research conclusions
CTCA is feasible with submillisievert radiation dose in most children with KD.
Research perspectives
CTCA has the potential to be an important adjunctive imaging modality in children with KD. To confirm our results multicentric study with larger sample size would be required.
