Al-Hussaniy HA. Letter to the Editor: Bridging the immunization gap in pediatric autoimmune disorders - insights from inflammatory bowel disease and vaccine response patterns. World J Clin Pediatr 2026; 15(2): 115247 [DOI: 10.5409/wjcp.v15.i2.115247]
Corresponding Author of This Article
Hany Akeel Al-Hussaniy, Professor, Department of Pharmacology, Al-Nisour University College, Baghdad Hayalkadsia, 602, 23, 17, Baghdad 10001, Iraq. hany_akeel2000@yahoo.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Correspondence
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jun 9, 2026 (publication date) through May 16, 2026
Times Cited of This Article
Times Cited (0)
Journal Information of This Article
Publication Name
World Journal of Clinical Pediatrics
ISSN
2219-2808
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Al-Hussaniy HA. Letter to the Editor: Bridging the immunization gap in pediatric autoimmune disorders - insights from inflammatory bowel disease and vaccine response patterns. World J Clin Pediatr 2026; 15(2): 115247 [DOI: 10.5409/wjcp.v15.i2.115247]
World J Clin Pediatr. Jun 9, 2026; 15(2): 115247 Published online Jun 9, 2026. doi: 10.5409/wjcp.v15.i2.115247
Letter to the Editor: Bridging the immunization gap in pediatric autoimmune disorders - insights from inflammatory bowel disease and vaccine response patterns
Hany Akeel Al-Hussaniy
Hany Akeel Al-Hussaniy, Department of Pharmacology, Al-Nisour University College, Baghdad 10001, Iraq
Author contributions: Al-Hussaniy HA contributed to wrote, corrected the article, analyzed the data, and writing the manuscript; the author had read and approved the final manuscript.
Conflict-of-interest statement: The author declares that he has no conflict of interest to disclose.
Corresponding author: Hany Akeel Al-Hussaniy, Professor, Department of Pharmacology, Al-Nisour University College, Baghdad Hayalkadsia, 602, 23, 17, Baghdad 10001, Iraq. hany_akeel2000@yahoo.com
Received: October 14, 2025 Revised: November 20, 2025 Accepted: February 2, 2026 Published online: June 9, 2026 Processing time: 213 Days and 9.3 Hours
Abstract
Autoimmune diseases represent serious conditions characterized by immune dysregulation, which compromises the body’s defense mechanisms and affects responses to infections and Vaccines. In addition to this, the treatment of these diseases involves mostly immunosuppressant’s. I read with great interest the study published in the World Journal of Clinical Pediatrics by Makarova et al, examining vaccines and antibody levels in children with inflammatory bowel disease (IBD), with a focus on enhancing children’s immune responses. Children with autoimmune diseases often show poor response to vaccines, which is attributed to their health condition and the immunosuppressive drugs used in treatment. One of the effective ways to protect these people in general and the children in specific is to follow personalized vaccination plans, or as mentioned in the research being discussed, to carry out revaccination and conduct serology tests and immunoglobulin G to ensure the effectiveness of vaccination plans. Those with diseases similar to IBD, and related diseases should conduct periodic checks after vaccination.
Core Tip: Children with inflammatory bowel disease (IBD) may be more susceptible to other autoimmune diseases. They may also not get an adequate response to vaccines because of the medications they take to suppress their immunity. Recent studies have addressed this issue, especially in people with IBD, antibody levels, and vaccines, and their potential effectiveness, particularly against rubella and hepatitis B.
