©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Angina bullosa hemorrhagica an enigmatic oral disease
Javier Alberdi-Navarro, María Luisa Gainza-Cirauqui, María Prieto-Elías, José Manuel Aguirre-Urizar, Oral Medicine and Oral and Maxillofacial Pathology Units, Dental Clinic Service, Master in Oral Pathology, Department of Stomatology II, UFI 11/25, University of the Basque Country/EHU, 48950 Leioa, Spain
María Luisa Gainza-Cirauqui, Department of Dental Surgery, Faculty of Dental Surgery, University of Malta, 2080 Msida, Malta
Author contributions: Alberdi-Navarro J and Aguirre-Urizar JM designed study; Alberdi-Navarro J, Gainza-Cirauqui ML and Prieto-Elías M contributed to bibliographic research; Alberdi-Navarro J and Prieto-Elías M drafted paper; Gainza-Cirauqui ML and Aguirre-Urizar JM contributed to critical review.
Conflict-of-interest: The authors have no conflict of interest to declare.
Correspondence to: José Manuel Aguirre-Urizar, PhD, Oral Medicine and Oral and Maxillofacial Pathology Units, Dental Clinic Service, Master in Oral Pathology, Department of Stomatology II, UFI 11/25, University of the Basque Country/EHU, Barrio Sarrera s/n, 48950 Leioa, Spain. josemanuel.aguirre@ehu.es
Telephone: +34-94-6015711
Received: October 15, 2014
Peer-review started: October 20, 2014
First decision: December 17, 2014
Revised: December 28, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: February 20, 2015
Processing time: 138 Days and 22 Hours
Peer-review started: October 20, 2014
First decision: December 17, 2014
Revised: December 28, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: February 20, 2015
Processing time: 138 Days and 22 Hours
Core Tip
Core tip: Although it is an uncommon disease, the angina bullosa hemorrhagica should be considered in the differential diagnosis of oral vesiculo-bullous processes. Acknowledging this entity will help in differentiating it from important mucocutaneous and hematological diseases such as pemphigus vulgaris, mucous membrane pemphigoid or coagulation disorders. In this review we analyze the main etiopathogenic, clinicopathological, diagnostic and therapeutic aspects of this enigmatic oral condition.