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World J Respirol. Jul 28, 2015; 5(2): 152-159
Published online Jul 28, 2015. doi: 10.5320/wjr.v5.i2.152
Role of hydrogen sulphide in airways
Apostolia Hatziefthimiou, Rodopi Stamatiou
Apostolia Hatziefthimiou, Rodopi Stamatiou, Laboratory of Physiology, Department of Medicine, School of Health Sciences, University of Thessaly, 41110 Larissa, Greece
Author contributions: All authors contributed equally; all authors read and approved the final manuscript for publication.
Conflict-of-interest statement: The authors declare that there is no conflict of interest.
Correspondence to: Apostolia Hatziefthimiou, Associate Professor of Medical Physiology, Laboratory of Physiology, Department of Medicine, School of Health Sciences, University of Thessaly, Panepistimiou 3, Biopolis, 41110 Larissa, Greece. axatzi@med.uth.gr
Telephone: +30-24-10685561 Fax: +30-24-10685555
Received: December 23, 2014
Peer-review started: December 23, 2014
First decision: January 20, 2015
Revised: February 4, 2015
Accepted: March 5, 2015
Article in press: March 9, 2015
Published online: July 28, 2015
Processing time: 224 Days and 10.7 Hours
Core Tip

Core tip: Hydrogen sulfide (H2S) is a metabolite produced in mammalian organisms both in physiological and in pathological conditions. The measured levels appear differentiated in inflammatory airway diseases, showing the need to acknowledge H2S not only as a metabolic mediator but as a signaling biomarker as well. This could be of clinical importance since H2S levels could be used in order to access staging or treatment efficiency in patients suffering from airway diseases.