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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Obstet Gynecol. Feb 10, 2016; 5(1): 110-117
Published online Feb 10, 2016. doi: 10.5317/wjog.v5.i1.110
Published online Feb 10, 2016. doi: 10.5317/wjog.v5.i1.110
Overview of embryonal rhabdomyosarcoma of cervix in women over 40-year-old
Malala Razakanaivo, Joseph Ravoahangy Andrianavalona University Hospital, Antananarivo 101, Madagascar
Nam P Nguyen, Radiation Oncology, Howard University Hospital, Washington, DC 20060, United States
Juliette Thariat, Antoine-Lacassagne Cancer Center, University Nice Sophia Antipolis, 06189 Nice Cedex, France
Juliette Thariat, Rare Cancer Network, Lausanne 1011, Switzerland
Vincent Molinie, Department of Pathology, University Hospital of Martinique, Fort-de-France 97200, Martinique
Anne-Therese Vlastos, Geneva Gynecology and Obstetrics, Place des Philosophes, 1205 Geneva, Switzerland
Claire Verschraegen, Division of Hematology Oncology, University of Vermont Cancer Center, Burlington, VT 05405, United States
Vincent Vinh-Hung, Radiation Oncology, University Hospital of Martinique, Fort-de-France 97200, Martinique
Vincent Vinh-Hung, Radiotherapy Department, UZ Brussel, Vrije Universiteit Brussel, 1090 Jette, Belgium
Nam P Nguyen, Juliette Thariat, Vincent Vinh-Hung, International Geriatric Radiotherapy Group (http://igrg.org/), Washington, DC 20060, United States
Author contributions: Original concept and design were developed by Nguyen NP, Thariat J and Vinh-Hung V; literature search was performed by Razakanaivo M, Nguyen NP, Verschraegen C and Vinh-Hung V; data revisions were carried out by Nguyen NP, Thariat J, Verschraegen C and Vinh-Hung V; statistical analyses were performed by Vinh-Hung V; Razakanaivo M, Molinie V and Vlastos AT contributed to the writing of the manuscript; all authors approved the final version.
Conflict-of-interest statement: The authors have no conflicts of interests to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Vincent Vinh-Hung, MD, PhD, Radiation Oncology, University Hospital of Martinique, Hôpital Clarac, Bd Pasteur, Fort-de-France 97200, Martinique. anhxang@gmail.com
Telephone: +596-696-542019 Fax: +596-596-632254
Received: June 27, 2015
Peer-review started: June 30, 2015
First decision: August 16, 2015
Revised: November 11, 2015
Accepted: December 13, 2015
Article in press: December 14, 2015
Published online: February 10, 2016
Processing time: 218 Days and 6 Hours
Peer-review started: June 30, 2015
First decision: August 16, 2015
Revised: November 11, 2015
Accepted: December 13, 2015
Article in press: December 14, 2015
Published online: February 10, 2016
Processing time: 218 Days and 6 Hours
Core Tip
Core tip: The present review of adult cervical embryonal rhabdomyosarcoma case series summarizes 5 studies reporting on 47 female patients, 22 of whom were > 40-year-old. Women over 40 had worse disease-free survival but also received less chemotherapy administration. Although radiotherapy was not often used, the longest survival in the > 40 age group was observed among those who received radiotherapy, including a case with resected lung metastasis. The review argues for multimodality management in this rare disease.