Universal screening for hemoglobinopathies in today's multi-ethnic societies: How and when

doi:10.5317/wjog.v4.i4.86

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 4, Issue 4

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (17006)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-3) series.

Item

Count

PDF

958

WORD

446

HTML

8482

Figures (1-3)

726

Tables (1-3)

573

Sum=11185

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

660

Download

1839

Sum=2499

Publishing Process of This Article

Item

Count

Browse

1260

Download

2067

Sum=3327

Nov 10, 2015 (publication date) through Mar 5, 2026

Times Cited of This Article

Times Cited (1)

Journal Information of This Article

Publication Name

World Journal of Obstetrics and Gynecology

ISSN

2218-6220

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Obstet Gynecol. Nov 10, 2015; 4(4): 86-94
Published online Nov 10, 2015. doi: 10.5317/wjog.v4.i4.86

Universal screening for hemoglobinopathies in today's multi-ethnic societies: How and when

Piero C Giordano

Piero C Giordano, Department of Human and Clinical Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands

Author contributions: The author solely contributed to this paper.

Conflict-of-interest statement: The author declares that this review is not subjected to submission to ethical codes and that no conflicts of interest are present.

Correspondence to: Piero C Giordano, PhD, Emeritus Associated Professor, Clinical Biochemical Molecular Geneticist, Consultant at the Hemoglobinopathies Laboratory, Department of Human and Clinical Genetics, Leiden University Medical Center, Einthovenweg 20, 2300 RC Leiden, The Netherlands. p.c.giordano@lumc.nl

Telephone: +31-71-5269800 Fax: +31-71-5268276

Received: July 19, 2015
Peer-review started: July 27, 2015
First decision: September 17, 2015
Revised: September 27, 2015
Accepted: October 16, 2015
Article in press: October 19, 2015
Published online: November 10, 2015
Processing time: 113 Days and 16.8 Hours

Core Tip

Core tip: All women in most modern countries are offered screening for rhesus antagonism and infectious diseases early in pregnancy. Hemoglobinopathy (HBP) screening done together with rhesus screening using an inexpensive routine high performance liquid chromatography or capillary electrophoresis analysis could identify all women carriers of the frequent traits associated with the severe forms of HBP. Subsequent partner analysis could identify all couples at risk to be confirmed by molecular analysis in time for prenatal diagnosis when requested. This procedure will allow the prevention task to be offered at the most logical moment and by the most specialized hands of the gynecologists and obstetricians in collaboration with the local labs and the genetic counselors.