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Pyrzak A, Foley OW, Grace AK, Barber EL. Effect of Centering Preoperative Counseling on Patient-Reported Anxiety in Patients with Gynecologic Malignancies. J Gynecol Surg 2022. [DOI: 10.1089/gyn.2022.0107] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/29/2022] Open
Affiliation(s)
- Adam Pyrzak
- The Southeastern Permanente Medical Group, Atlanta, Georgia, USA
- Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
- Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA
| | - Olivia W. Foley
- Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
- Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA
- Northwestern Hospital Obstetrics and Gynecology, Division of Gynecologic Oncology and Prentice Women's Hospital, Chicago, Illinois, USA
| | - Anne K. Grace
- Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
| | - Emma L. Barber
- Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
- Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA
- Surgical Outcomes and Quality Improvement Center, Institute for Public Health in Medicine, Chicago, Illinois, USA
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Manne SL, Kashy DA, Kissane DW, Ozga M, Virtue SM, Heckman CJ. The course and predictors of perceived unsupportive responses by family and friends among women newly diagnosed with gynecological cancers. Transl Behav Med 2020; 9:682-692. [PMID: 30189025 DOI: 10.1093/tbm/iby087] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/14/2022] Open
Abstract
Perceived unsupportive responses from close others play an important role in psychological adaptation of patients with cancer. Little is known about whether these negative responses change after someone experiences a serious life event, and even less is known about the individual characteristics and related factors that might contribute to both the levels of and changes in perceived unsupportive responses over the course of adaptation to an experience. This longitudinal study aimed to evaluate changes in perceived unsupportive behavior from family and friends among women newly with gynecologic cancer as well as initial demographic, disease, and psychological factors that predict the course of perceived unsupportive behavior over time. Women (N = 125) assigned to the usual care arm of a randomized clinical trial comparing a coping and communication intervention with a supportive counseling intervention to usual care completed six surveys over an 18 month period. Growth models using multilevel modeling were used to predict unsupportive responses over time. Average levels of perceived unsupportive responses from family and friends were low. Unsupportive responses varied from patient to patient, but patients did not report a systematic change in perceived unsupportive responses over time. Cultivating meaning and peace and coping efficacy were associated with fewer perceived unsupportive responses as well as reductions in perceived unsupportive responses over time. Emotional distress, cancer concerns, functional impairment, holding back sharing concerns, and cognitive and behavioral avoidance predicted higher perceived unsupportive responses over time. The findings are discussed in terms of the self-presentation theory and social network responses to persons undergoing difficult life events.
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Affiliation(s)
- Sharon L Manne
- Department of Medicine, Rutgers Robert Wood Johnson Medical School, Section of Population Science, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA
| | - Deborah A Kashy
- Department of Psychology, Michigan State University, East Lansing, MI, USA
| | - David W Kissane
- Department of Psychiatry, Monash University, Melbourne, Australia
| | - Melissa Ozga
- Memorial Sloan Kettering Cancer Center, New York, NY, USA
| | - Shannon Myers Virtue
- Clinical Psychology, Helen Graham Cancer Center, Christiana Care Health System, Wilmington, DE, USA
| | - Carolyn J Heckman
- Cancer Prevention and Control Program, Fox Chase Cancer Center, Temple Health, Philadelphia, PA, USA
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Lopes AC, Bacalhau R, Santos M, Pereira M, Pereira MG. Contribution of Sociodemographic, Clinical, and Psychological Variables to Quality of Life in Women with Cervical Cancer in the Follow-Up Phase. J Clin Psychol Med Settings 2019; 27:603-614. [PMID: 31292805 DOI: 10.1007/s10880-019-09644-0] [Citation(s) in RCA: 6] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/09/2023]
Abstract
This study evaluates the contribution of sociodemographic, clinical, and psychological variables to quality of life (QoL) of women with cervical cancer in the follow-up phase. This cross-sectional study, conducted at the Portuguese Oncology Institute of Lisbon, included 200 women with cervical cancer during follow-up. Patients were assessed on QoL (EORTC QLQ-C30), body image and specific symptoms (EORTC QLQ-CX24), psychological morbidity (HADS), social support (SSSS), emotional expression (CECS), and spirituality (SpREUK). Education and social support contributed positively to QoL, whereas body image and symptoms contributed negatively. Body image played a moderating role in the relationship between depression and QoL, but not between anxiety and QoL. Spirituality and emotional expression did not moderate the relationship between anxiety/depression and QoL. Health professionals should reference and monitor women with cervical cancer, providing support at the diagnosis and follow-up phase since physical and psychological symptoms, resulting from the disease, remain after the end of treatment and contribute negatively to their QoL. Interventions should focus on these particular outcomes to promote patients' QoL.
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Affiliation(s)
- Ana Clara Lopes
- School of Psychology, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal
| | - Rosário Bacalhau
- School of Psychology, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal
| | - Martim Santos
- School of Psychology, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal
| | - Marta Pereira
- School of Psychology, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal
| | - M Graça Pereira
- School of Psychology, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
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Igwe E, Woodburn J, Davolos J, Shollenberger C, Miller SM, Hernandez E, Ferriss JS. Patient perceptions and willingness to participate in clinical trials. Gynecol Oncol 2016; 142:520-4. [PMID: 27372403 DOI: 10.1016/j.ygyno.2016.06.015] [Citation(s) in RCA: 18] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/06/2016] [Revised: 06/20/2016] [Accepted: 06/25/2016] [Indexed: 10/21/2022]
Abstract
OBJECTIVE To evaluate gynecologic oncology patients' perceptions and willingness to participate in randomized clinical trials (RCT) among an inner city population. METHODS Informed consent was obtained. Demographics were collected and willingness to participate in a RCT was measured by the Attitudes on Randomized Trials Questionnaire (ARTQ). The Hospital Anxiety and Depression Scale estimated levels of anxiety and depression. A Perception Survey was created and tested as a screening tool for patients considering RCTs. Standard statistical tests were used. RESULTS One hundred and one women participated, 54 (53.5%) were black, 31 (30.7%) were white, non-Hispanic and 15 (14.9%) were Hispanic. Screening for anxiety and depression revealed an 18.8% rate of moderate to severe anxiety and an 11.9% rate of moderate to severe depression. Willingness to participate in a RCT as measured by ARTQ scores was not significantly associated with race, levels of anxiety or depression. Twenty-eight percent of women would agree to participate in a clinical trial at baseline. An additional, 33 (32.7%), for a total of 61.4%, indicated agreement after targeted education with no statistical differences by race or psychological stressor. However, sixty-one percent of these women were black. The Perception Survey approximated the results of the ARTQ with reasonable accuracy (AUC 0.758, p<0.001) CONCLUSIONS: Neither race nor psychological stressor were significant indicators of willingness to participate in a RCT. Targeted education resulted in a majority of patients indicating willingness to participate in trials, especially among black women. Additionally, a novel screening tool was tested and performed well in this setting.
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Affiliation(s)
- Elena Igwe
- Department of Obstetrics, Gynecology & Reproductive Sciences, Lewis Katz School of Medicine at Temple University & Fox Chase Cancer Center, Philadelphia, PA, United States.
| | - Julie Woodburn
- Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States
| | - Jacyln Davolos
- Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States
| | - Cori Shollenberger
- Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States
| | - Suzanne M Miller
- Fox Chase Cancer Center/ Temple University Health System, Philadelphia, PA, United States
| | - Enrique Hernandez
- Department of Obstetrics, Gynecology & Reproductive Sciences, Lewis Katz School of Medicine at Temple University & Fox Chase Cancer Center, Philadelphia, PA, United States
| | - J Stuart Ferriss
- Department of Obstetrics, Gynecology & Reproductive Sciences, Lewis Katz School of Medicine at Temple University & Fox Chase Cancer Center, Philadelphia, PA, United States
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Walker AJ, Benrubi ID, Ward KK. Care of survivors of gynecologic cancers. World J Obstet Gynecol 2016; 5:140-149. [DOI: 10.5317/wjog.v5.i2.140] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 06/29/2015] [Revised: 11/16/2015] [Accepted: 02/24/2016] [Indexed: 02/05/2023] Open
Abstract
The number of cancer survivors is increasing and most healthcare providers will manage patients who have completed therapy for malignancy at some point. The care of survivors of gynecologic malignancies may seem daunting in a busy general gynecology practice. This paper intends to review the literature and suggest management of these women for the general gynecologist.
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Bugan I, Karagoz Z, Altun S, Djamgoz MBA. Gabapentin, an Analgesic Used Against Cancer-Associated Neuropathic Pain: Effects on Prostate Cancer Progression in anIn VivoRat Model. Basic Clin Pharmacol Toxicol 2015; 118:200-7. [DOI: 10.1111/bcpt.12484] [Citation(s) in RCA: 15] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/02/2015] [Accepted: 08/27/2015] [Indexed: 12/13/2022]
Affiliation(s)
- Ilknur Bugan
- Department of Biology; Faculty of Science; Istanbul University; Vezneciler Istanbul Turkey
| | - Zeynep Karagoz
- Department of Biology; Faculty of Science; Istanbul University; Vezneciler Istanbul Turkey
| | - Seyhan Altun
- Department of Biology; Faculty of Science; Istanbul University; Vezneciler Istanbul Turkey
| | - Mustafa B. A. Djamgoz
- Department of Life Sciences; Sir Alexander Fleming Building; Imperial College London; South Kensington Campus; London UK
- Biotechnology Research Centre; Cyprus International University; Haspolat North Cyprus
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