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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Neurol. Sep 19, 2025; 11(1): 110105
Published online Sep 19, 2025. doi: 10.5316/wjn.v11.i1.110105
Published online Sep 19, 2025. doi: 10.5316/wjn.v11.i1.110105
Trends and disparities in mortality from comorbid non-insulin-dependent diabetes mellitus and stroke (1999-2022): A retrospective analysis
Sardar Muhammad Imran Khan, Department of Cardiology, National University of Medical Sciences, Rawalpindi 04616, Punjab, Pakistan
Hamza Asif, Muhammad Hassan Raza, Department of Medicine, Nishtar Medical University, Multan 66000, Punjab, Pakistan
Muhammad Waqas, Department of Cardiology, Wah Medical College, Islamabad 04433, Pakistan
Syed Zahid Ali, Department of Neurology, University of Louisville School of Medicine, Louisville, KY 40208, United States
Muneeb Khawar, Muneeb Saifullah, Department of Medicine, King Edward Medical University, Lahore 05450, Punjab, Pakistan
Abbas Muhammad Mehdi, Department of Medicine, International School of Medicine, International University of Kyrgyzstan, Bishkek 720065, Kyrgyzstan
Author contributions: Khan SMI, Asif H, Raza MH, Waqas M, Ali SZ, Khawar M, Saifullah M, Mehdi AM led conceptualization, methodology, and formal analysis, and wrote and reviewed the manuscript; all authors contributed to the software, validation, and investigation, and thoroughly reviewed and endorsed the final manuscript.
Institutional review board statement: We respectfully inform you that this study did not involve the recruitment or enrollment of human subjects. It is based entirely on secondary analysis of publicly available, de-identified mortality data. Therefore, the requirement to upload an Institutional Review Board Approval Form or Document is not applicable.
Informed consent statement: We respectfully inform you that this study did not involve the recruitment or enrollment of human subjects. It is based entirely on secondary analysis of publicly available, de-identified mortality data. Therefore, the requirement to upload an Informed Consent Form is not applicable.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Not applicable.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abbas Muhammad Mehdi, MD, Department of Medicine, International School of Medicine, International University of Kyrgyzstan, 6 Seven April Street, Bishkek 720065, Kyrgyzstan. malikmehdi0508@gmail.com
Received: May 29, 2025
Revised: July 12, 2025
Accepted: September 10, 2025
Published online: September 19, 2025
Processing time: 111 Days and 13.5 Hours
Revised: July 12, 2025
Accepted: September 10, 2025
Published online: September 19, 2025
Processing time: 111 Days and 13.5 Hours
Core Tip
Core Tip: The growing mortality burden from coexisting type 2 diabetes and stroke highlights widening disparities across demographic and regional lines. Targeted, context-specific interventions are urgently needed to address these inequities.