Role of hematological parameters in pathogenesis of diabetes mellitus: A review of the literature

doi:10.5315/wjh.v10.i3.25

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World Journal of Hematology

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2218-6204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hematol. Mar 24, 2023; 10(3): 25-41
Published online Mar 24, 2023. doi: 10.5315/wjh.v10.i3.25

Role of hematological parameters in pathogenesis of diabetes mellitus: A review of the literature

Sana Rafaqat, Saira Rafaqat

Sana Rafaqat, Department of Biotechnology, Lahore College for Women University, Lahore 5400, Pakistan

Saira Rafaqat, Department of Zoology, Lahore College for Women University, Lahore 5400, Pakistan

Author contributions: All authors contributed equally to this work.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Sana Rafaqat, PhD, Research Fellow, Department of Biotechnology, Lahore College for Women University, Jail road, Lahore 5400, Pakistan. sana.rafaqat44@gmail.com

Received: December 7, 2022
Peer-review started: December 7, 2022
First decision: December 20, 2022
Revised: January 3, 2023
Accepted: March 9, 2023
Article in press: March 9, 2023
Published online: March 24, 2023
Processing time: 105 Days and 0.5 Hours

Core Tip

Core Tip: This review paper aims to determine the association between hematological parameters and diabetes with recent major advances, discoveries, significant gaps in the literature, current debates, and potential directions for future research. There are numerous hematological parameters, but this review article only focuses on red blood cells, hemoglobin, hematocrit, red blood cells indices such as mean cellular/corpuscular volume, mean cellular/corpuscular hemoglobin, mean cellular/corpuscular hemoglobin concentration, and red cell distribution width, platelet count, white blood cells, lymphocytes, neutrophils, monocytes, eosinophils, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio, which play a pathophysiological role in different types of diabetes mellitus.