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World J Anesthesiol. Mar 27, 2017; 6(1): 14-21
Published online Mar 27, 2017. doi: 10.5313/wja.v6.i1.14
Massive transfusion: An update for the anesthesiologist
Charles Fredericks, John C Kubasiak, Caleb J Mentzer, James R Yon
Charles Fredericks, John C Kubasiak, Department of General Surgery, Rush University Medical Center, Chicago, IL 60612, United States
Caleb J Mentzer, Department of Trauma, University of Miami Ryder Trauma Center, Miami, FL 79844, United States
James R Yon, Department of Trauma and Acute Care Surgery, Swedish Medical Center, Englewood, CO 80113, United States
Author contributions: Fredericks C, Kubasiak JC and Mentzer CJ each wrote sections of the paper; Yon JR performed the literature review and edited the paper in addition to writing a section of the paper.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Correspondence to: James R Yon, MD, Department of Trauma and Acute Care Surgery, Swedish Medical Center, 499 E Hampden Blvd., Suite 400, Englewood, CO 80113, United States. james.yon@healthonecares.com
Telephone: +1-941-6185426
Received: August 29, 2016
Peer-review started: September 1, 2016
First decision: September 29, 2016
Revised: December 8, 2016
Accepted: December 16, 2016
Article in press: December 19, 2016
Published online: March 27, 2017
Processing time: 203 Days and 14.8 Hours
Core Tip

Core tip: Recognizing the patient who requires massive transfusion early is key to the most optimal outcome. Once recognized, massive transfusion protocols (MTP) should be initiated and continued until normal physiologic parameters are reached and definitive control of bleeding is achieved. Hospitals should develop their own MTP, guided by the literature, and according to their specific needs and patient populations.