Standardized quantitative measurements of wrist cartilage in healthy humans using 3T magnetic resonance imaging

Table 1 Variables of the magnetic resonance imaging sequences

Sequence	FOV (mm)	ST (mm)	RT (ms)	ET (ms)	AT (S)	Matrix size	Resolution (mm)
3D DESS	130 × 130	0.5	14	5.2	330	256 × 256	0.5 × 0.5
3D VIBE	130 × 130	0.5	10	3.38	290	256 × 256	0.5 × 0.5

FOV: Field of view; ST: Slice thickness; ET: Echo-time; RT: Repetition time; AT: Acquisition time; VIBE: Volume interpolated breath hold examination; DESS: Dual echo steady state.

Table 2 Quantitative measurements of cartilage

	VIBE	DESS
M1	292.4 ± 39	270.4 ± 50.61
M2	292.3 ± 43.8	274.1 ± 37.41
M3	295.9 ± 41.2	272.9 ± 49.11
CVb	14.1	16.8
CVw	2.4	4.8
ICC1	0.96 (0.88-0.98)	0.93 (0.78-0.98)
ICC2	0.98 (0.92-0.99)	0.92 (0.76-0.97)

¹Significantly different than the corresponding measurement using the VIBE sequence. Values are presented as means ± SD. M1 and M2 refer to both measurements performed by the same operator. M3 refers to the measurement performed by the second operator. CVb and CVw refer to Between-subject and within subject coefficients of variation considering the measurements performed by the first operator. ICC1 and ICC2: Intraclass coefficient with 95%CI calculated considering both measurements performed by the same operator and measurements performed by both operators. CV: Coefficient of variation; ICC: Intra-class correlation coefficients; VIBE: Volume interpolated breath hold examination; DESS: Dual echo steady state.