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Systematic Reviews
Copyright: ©Author(s) 2026.
World J Orthop. Apr 18, 2026; 17(4): 116521
Published online Apr 18, 2026. doi: 10.5312/wjo.v17.i4.116521
Table 1 Study and patient characteristics
Ref.
Study design
Trait of participants
Number of participants
Intervention
Type of imagery
Pre-op session
Duration
Frequency
Age (year)
Sex (male/total)
Mean follow-up
Almuhaya et al[12], 2023RCTCases: 13 ACLR only, 4 ACLR + MMR, 1 ACLR + both (MMR and LMR)Cases: 16Cases: Structured education + standard physiotherapyVirtual interactive structured educational session via Zoom platform including a series of topics related to the surgery and the rehabilitation process prepared with pictures and graphsNo1 week8 five days in a week, 2 four days, 8 three or less days26 (6)35/351 week
Controls: 12 ACLR only, 2 ACLR + MMR, 1 ACLR + LMR, 2 ACLR + bothControls: 14Controls: Standard physiotherapy
Lee et al[14], 2023RCTACL reconstructionCases: 55Cases: Smartphone app-based behavioral intervention + standard physiotherapyA smartphone app delivering the intervention through text, pictorials, and videos on how post-surgery home-based exercises and rehabilitations will be done, behavior change techniquesNo16 weeksNR27.82 (8.73)NR16 weeks
Controls: 41Controls: Standard physiotherapy
Brewer et al[6], 2022RCTACL reconstructionCases: 34Cases: Interactive cognitive-behavioral multimedia program + standard physiotherapyIntroductory information and instructions on: (1) General information; (2) Surgery; and (3) Rehabilitation. Videos in which an orthopedic surgeon discussed the sensory and procedural aspects associated with the corresponding section of the program. Anatomical and surgical animations, video and still images of preoperative and postoperative rehabilitation exercises, video clips of former ACL reconstruction patients describing their experiences with ACL surgery and rehabilitation, a graph of pain over the rehabilitation process, and written text were among the means by which procedural and sensory information and modeling of adaptive coping responses. Links to online resources, personal accounts of and recommendations for dealing with ACL surgery and rehabilitation from former patientsYes24 weeksWeekly35.01 (11.98)39/6924 weeks
Placebos: 35Placebo: Printed educational materials + standard physiotherapy
D’Isanto et al[13], 2022RCTACL reconstructionCases: 15Cases: VRGI and MT + standard physiotherapySuggestions for imagining internal images related to the use of the affected limb in one or more functional tasks and also through the mirror box, working with the vision of a video in which, through a background voice, the subject was asked to visualize specific sports movements and gesturesNo20 weeks3 times per week (training frequency was 5/week with a session length of 60 minutes, with MT added
3 times/week for 20-25 minutes after the end of the conventional physical therapy)
Cases: 33 (1.8)NR20 weeks
Controls: 15Controls: PhysiotherapyControls: 32 (1.6)
Lyles et al[17], 2014RCTACL reconstructionCases: 15Cases: Mirror therapy + standard physiotherapyAffected leg was placed behind a self-made mirror (non-reflecting side) and non-affected leg was placed in front of the mirror (reflecting side). Patients were instructed to observe the reflected leg into the mirror while performing the exercises and then attempt the same exercises with the involved legNo6 daysOnce a dayCases: 33.13 (6.99)Cases: 10/156 days
Controls: 15Controls: Standard physiotherapyControls: 32.4 (5.66)Controls: 9/15
Rhim et al[8], 2020RCTACL reconstructionCases: 10Cases: Modeling intervention + standard physiotherapyCases: Six modeling videos of semi-structured interviews and models who discussed their injury experience, expectations, and recovery and performed postoperative time-matchedYes24 weeksNRCases: 27.1 (9.5), placebos: 32.2 (12.2), controls: 26.8 (7.9)Cases: 9/10, placebos: 8/11, controls: 10/1124 weeks
Placebos: 11Placebos: Placebo videos + standard physiotherapyTasks and rehabilitation exercises. Six videos were similar in length (5 minutes)
Controls: 11Controls: Standard physiotherapyReflected 6 different time points: Preoperative period, from hospitalization to 2 weeks, 2 weeks to 6 weeks, 6 weeks to 3 months, 3 months to 6 months, and 6 months and beyond following ACLR; placebos: Videos of PowerPoint slides including epidemiology of ACL injuries, anatomy of ACL, and mechanisms of ACL injury, and describing rehabilitation exercises with words
Levinger et al[7], 2017RCTACL reconstructionCases: 10Cases: Internet-based resource + usual rehabilitationVideo and images on ACL reconstruction, expected milestones during the recovery process, strategies to overcome distress associated with the injury, and recommended physiotherapy exercisesNo12 weeksOn a daily basis for the first week following the surgeryCases: 32.2 (10.2)Cases: 6/10, placebos: 4/712 weeks
Placebos: 7Placebos: Restricted access to internet-based resource + usual rehabilitationThree times per week for weeks 2-3 following the surgeryPlacebos: 28.5 (9.1)
Once a week for weeks 4-12 following the surgery
Zaffagnini et al[9], 2013RCTACL reconstructionCases: 51Cases: Therapeutic vision videos + standard physiotherapyCases: Art video producing therapeutic insightNo8 weeks3 times per week33 (17)80/10112 weeks
Placebos: 50Placebos: Videos of unfavorable information + standard physiotherapyPlacebos: Art video with an insight unfavorable to the psychological recovery
Maddison et al[16], 2012RCTACL reconstructionCases: 13Cases: Mental rehearsal of rehabilitation goals + standard physiotherapyNine individual sessions of mental rehearsal of activities to achieve physical rehabilitation goals including cognitive, motivational, and healing imagery; cognitive imagery was used to rehearse rehabilitation exercises, using both visual and kinaesthetic modalities. Motivational imagery was used to set goals, control arousal levels, and increase self-confidence. Healing imagery was used to imagine the physiological processes taking place during rehabilitationNo24 weeksNR34.86 (8.84)13/2124 weeks
Controls: 8Controls: Standard physiotherapy
Lebon et al[4], 2012RCTACL reconstructionCases: 7Cases: Imagining muscle contractions + standard physiotherapy3 blocks of 10 imagined contractions, with a 10-second rest period between
rehearsals and 2-minute rest period between blocks
No5 weeksEvery 2 days28.5 (5)NR5 weeks
Placebos: 5Placebos: Neutral mental task (crossword or calculation) + standard physiotherapy
Maddison et al[15], 2006RCTACL reconstructionCases: 30Cases: Coping-model video + standard physiotherapyTwo coping model videos of edited interviews and models performing rehabilitation exercises; first video pre-op to 2 weeks post-op (9-minute) and second video 2 weeks to 6 weeks post-op (7-minute)Yes6 weeksNR30NR6 weeks
Controls: 28Controls: Standard physiotherapy
Cupal and Brewer[3], 2001RCTACL reconstructionCases: 10Cases: Mental rehearsal of rehabilitation goals + standard physiotherapyVideos of patient’s arthroscopic procedure, facilitating knee flexibility and ROM, edema reduction, knee strength, position sense, anxiety reduction, anatomical and neurological mental comparisonNo24 weeksEvery 2 weeks28.2 (8.2)16/3024 weeks
Placebos: 10Placebos: Peaceful scene imagery + attention, encouragement, and support + standard physiotherapy
Controls: 10Controls: Standard physiotherapy
Table 2 Outcome evaluations between intervention and control groups
Ref.
Measured outcomes
Results
Almuhaya et al[12], 2023Kinesiophobia (TSK)Improved TSK (P = 0.026) and ACL-RSI (P = 0.009) in cases than controls, no significant difference in IKDC (P = 0.42) between groups
Return to sport (ACL-RSI)
Functional status (IKDC)
Lee et al[14], 2023Knee strength (biodex isokinetic dynamometer)No significant difference in muscle strength (P = 0.25 to 0.96), knee laxity (P = 0.96), and subjective knee evaluation (P = 0.99) between groups
Knee laxity (KT1000)
Functional status (IKDC)
D’Isanto et al[13], 2022Pain (VAS score)Greater psychological readiness (P < 0.01) and lower postoperative pain in cases than controls
Psychological readiness (ACL-RSI)
Lyles et al[17], 2014Pain (VAS score)Improved postoperative pain (P = 0.0018), AROM (P = 0.0004), PROM (P = 0.0011), and Lysholm score (P = 0.044)
ROM (AROM and PROM in flexion)
Functional status (Lysholm)
Rhim et al[8], 2020Kinesiophobia (TSK)No significant difference in self-efficacy (P = 0.808), return to sport (P = 0.574), kinesiophobia (P = 0.888), and KOOS subscales (P = 0.236 to 0.916) between groups
Return to sport (ACL-RSI)
Self-efficacy (K-SES)
Functional status (KOOS)
Maddison et al[16], 2012Self-efficacy (AISEQ)Improved postoperative knee laxity (P < 0.05) favoring the intervention
Knee strength (180/second, 60/second)No significant difference for knee strength for extension at 180/second (P = 0.67) or 60/second (P = 0.48)
Knee laxity (KT1000)Fairly stable self-efficacy between weeks 6 to weeks 12 in cases than controls
Lebon et al[4], 2012Preoperative perception of pain (0-100 scale)Improved crutches (P < 0.01), walking (P = 0.01), and exercise (P < 0.05) SE in cases than controls only at predischarge, better IKDC 6 weeks postop, less crutches use time in cases than controls (P < 0.01)
Preoperative anxiety (STAI)
Self-efficacy (CSE, WSE, ESE)
Functional status (IKDC subjective and objective)No significant difference in preoperative anxiety reduction, preoperative perception of pain reduction (P = 0.52), and postoperative ROM (P = 0.36) between groups
ROM by goniometry
Crutches use time
Maddison et al[15], 2006Pain (0-10 scale)Improved pain in cases than controls (P < 0.05). Greater post-op knee strength in cases than controls (P < 0.02). Reduced re-injury anxiety in cases than controls (P < 0.05)
Reinjury anxiety (0-10 scale)
Knee strength (cybex 6000)
Isokinetic dynamometer)
Table 3 Outcome evaluations between intervention and placebo groups
Ref.
Measured outcomes
Results
Brewer et al[6], 2022Pain (NRS)Lower postoperative pain (P = 0.02), lower kinesiophobia (P = 0.77), improved postoperative symptoms (P = 0.002) in cases than controls
Kinesiophobia (TSK)No significant difference in flexion ROM (P = 0.99), extension ROM (P = 0.18), and knee laxity (P = 0.09) between groups
Subjective symptoms (KOS-SAS)
Knee laxity (KT1000)
ROM (flex and ext)
Rhim et al[8], 2020Kinesiophobia (TSK)No significant difference in self-efficacy (P = 0.808), return to sport (P = 0.574), kinesiophobia (P = 0.888), and KOOS subscales (P = 0.236 to 0.916) between groups
Return to sport (ACL-RSI)
Self-efficacy (K-SES)
Functional status (KOOS)
Levinger et al[7], 2017Self-efficacy (K-SES)No significant difference in KOOS subscales (P = 0.07-0.76), self-efficacy subscales (P = 0.42 and 0.71), kinesiophobia (P = 0.46), fear of activity (P = 0.96) between groups
Functional status (KOOS)
Kinesiophobia (TSK)
FABQ
Zaffagnini et al[9], 2013QOL (mental and physical SF-36)Improved subjective IKDC (P = 0.047), TKS (P = 0.0141) and time to crutches discharge (P = 0.0012). No significant difference in Tegner score, and SF-36 mental and physical status between groups
Kinesiophobia (TSK)
Functional (subjective and objective IKDC, Tegner)
Crutches use time
Lebon et al[4], 2012Isometric activation of the medial musculature (EMG during maximum knee extension)Greater postoperative musculature activity in cases than controls (P = 0.02). No significant difference in postoperative pain, ROM, effusion reduction, thigh circumference, LEFS score (P > 0.05) between groups
Pain (VAS score)
Ability to perform daily activities with lower extremity injury using the LEFS
Magnitude of surgical effusion and atrophy by the circumference of the knee above the kneecap and circumference of the thigh 15 cm above the kneecap
Knee ROM (goniometry)
Cupal and Brewer[3], 2001Pain (0-10 scale)Improved pain in cases than placebos (P < 0.05). Reduced re-injury anxiety in cases than placebos (P < 0.05). Greater post-op knee strength in cases than placebos (P < 0.003)
Reinjury anxiety (0-10 scale)
Knee strength (cybex 6000)
Isokinetic dynamometer