Altered lineage commitment of bone marrow mesenchymal stem cells in idiopathic osteonecrosis of the femoral head

doi:10.5312/wjo.v16.i12.113320

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Dec 18, 2025 (publication date) through May 9, 2026

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Dec 18, 2025; 16(12): 113320
Published online Dec 18, 2025. doi: 10.5312/wjo.v16.i12.113320

Table 1 Yield of mesenchymal stem cells obtained from femoral head samples, n (%)

Number of samples collected	Samples collected and processed	Progression to P1	Progression to P2
Number of samples (osteoarthritis controls)	34	30 (88)	7 (25)
Number of samples (ONFH)	26	20 (79)	9 (46)

Values rounded to nearest whole percent. P1, P2: Passages 1 and 2 (transfer to a new flask); ONFH: Osteonecrosis of the femoral head.

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Citation: Cardín-Pereda A, García-Sánchez D, Álvarez-Iglesias I, Cabello-Sanz J, Pérez-Campo FM. Altered lineage commitment of bone marrow mesenchymal stem cells in idiopathic osteonecrosis of the femoral head. World J Orthop 2025; 16(12): 113320
URL: https://www.wjgnet.com/2218-5836/full/v16/i12/113320.htm
DOI: https://dx.doi.org/10.5312/wjo.v16.i12.113320

Cardín-Pereda A, García-Sánchez D, Álvarez-Iglesias I, Cabello-Sanz J, Pérez-Campo FM. Altered lineage commitment of bone marrow mesenchymal stem cells in idiopathic osteonecrosis of the femoral head. World J Orthop 2025; 16(12): 113320 [PMID: 41480509 DOI: 10.5312/wjo.v16.i12.113320]

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