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New perspectives for articular cartilage repair treatment through tissue engineering: A contemporary review
Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy
Rosalia Leonardi, Department of Medical and Surgical Sciences, II Dental Unity, University of Catania, 95123 Catania, Italy
Francesca Maria Trovato, Department of Medical and Pediatric Sciences, Internal Medicine Division, University of Catania, 95123 Catania, Italy
Angelo Di Giunta, Sergio Castorina, Fondazione Mediterranea ‘‘G.B. Morgagni’’, 95125 Catania, Italy
Author contributions: Musumeci G researched the area and identified papers, wrote and structured the review; Castrogiovanni P, Loreto C, Szychlinska MA and Trovato FM reviewed and edited the paper; Di Giunta A provide the surgical materials; Leonardi R and Castorina S structured the paper.
Supported by The Department of Bio-Medical Sciences, University of Catania
Correspondence to: Giuseppe Musumeci, PhD, Department of Bio-Medical Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, 95123 Catania, Italy. g.musumeci@unict.it
Telephone: +39-095-3782043 Fax: +39-095-3782034
Received: October 21, 2013
Revised: January 27, 2014
Accepted: February 20, 2014
Published online: April 18, 2014
Processing time: 210 Days and 9.8 Hours
Revised: January 27, 2014
Accepted: February 20, 2014
Published online: April 18, 2014
Processing time: 210 Days and 9.8 Hours
Core Tip
Core tip: In this paper review we describe benefits and disadvantages of the established methods of cartilage regeneration that seem to have a better long-term effectiveness. We illustrated the anatomical aspect of the knee joint cartilage, the current state of cartilage tissue engineering through mesenchymal stem cells and biomaterials and in conclusion we provided a short overview on the rehabilitation after articular cartilage repair procedures.