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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Sep 18, 2025; 16(9): 110386
Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.110386
Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.110386
Short-term survivorship of antioxidant highly cross-linked polyethylene liners in total hip arthroplasty reported in American Joint Replacement Registry
Kirstin Jones, Amber M Muehlmann, Sarah M Melvin, Clinical Affairs, Exactech, Inc., Gainesville, FL 32653, United States
Ebru Oral, Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02114, United States
Colin T Penrose, Department of Orthopaedics, Midwest Center for Joint Replacement, Indianapolis, IN 46241, United States
Author contributions: Jones K and Penrose CT designed the research study; Jones K, Muehlmann AM, and Melvin SM performed the research; Jones K, Muehlmann AM, Melvin SM, Oral E, and Penrose CT wrote the manuscript; Jones K, Muehlmann AM, Oral E, and Penrose CT edited the manuscript; All authors have read and approve the final manuscript.
Institutional review board statement: This study is exempt from Institutional Review Board approval as outlined in the US Code of Federal Regulations, 45 CFR 46.102.
Informed consent statement: This study is exempt from informed consent.
Conflict-of-interest statement: Kirstin Jones, Amber M Muehlmann, and Sarah M Melvin are paid employees of Exactech. Dr. Oral has no conflicts of interest to declare. Dr. Penrose is a paid consultant for Exactech.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: No additional data are available from the authors for data sharing.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amber M Muehlmann, PhD, Clinical Affairs, Exactech, Inc., 2320 NW 66th Court, Gainesville, FL 32653, United States. amber.muehlmann@exac.com
Received: June 7, 2025
Revised: June 30, 2025
Accepted: July 29, 2025
Published online: September 18, 2025
Processing time: 97 Days and 7.5 Hours
Revised: June 30, 2025
Accepted: July 29, 2025
Published online: September 18, 2025
Processing time: 97 Days and 7.5 Hours
Core Tip
Core Tip: Short-term data from the American Joint Replacement Registry on the Novation and Alteon XLE hip liners reveal similar survivorship and reasons for revision compared to an aggregate group of all other antioxidant liners. Within this dataset there were no failures due to wear in the Novation and Alteon XLE groups.