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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Sep 18, 2025; 16(9): 109147
Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.109147
Published online Sep 18, 2025. doi: 10.5312/wjo.v16.i9.109147
Intra-articular treatments for hindfoot osteoarthritis
Fernanda Ferreira Gomes, Isnar Moreira de Castro Junior, Foot Specialized Attendance Center, National Institute of Traumatology and Orthopedics, Rio de Janeiro 20940-070, Brazil
Joao Antonio Matheus Guimaraes, Aline Cordeiro, Research Division, National Institute of Traumatology and Orthopedics, Rio de Janeiro 20940-070, Brazil
Isabela de Miranda Rosa, Eduardo B de Sousa, Department of General and Specialized Surgery, Faculty of Medicine, Fluminense Federal University (UFF), Rio de Janeiro 24070-090, Brazil
Author contributions: Gomes FF designed and performed research, and wrote the paper; Castro Junior IM designed research; Rosa IM performed research, and wrote the paper; Sousa EB performed research, and wrote the paper; and Cordeiro A designed and performed research, and wrote the paper.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Eduardo B de Sousa, MD, PhD, Department of General and Specialized Surgery, Faculty of Medicine, Fluminense Federal University (UFF), Rua Ataíde Parreiras 100, Rio de Janeiro 24070-090, Brazil. eduardobranco.joelho@gmail.com
Received: May 6, 2025
Revised: June 8, 2025
Accepted: August 11, 2025
Published online: September 18, 2025
Processing time: 133 Days and 11.3 Hours
Revised: June 8, 2025
Accepted: August 11, 2025
Published online: September 18, 2025
Processing time: 133 Days and 11.3 Hours
Core Tip
Core Tip: Hindfoot osteoarthritis (HFOA), whose prevalence has been increasing over the years, leads to pain, impaired function, and reduced quality of life. Moreover, it becomes symptomatic approximately 15 years earlier than hip and knee osteoarthritis, leading to the need for procedures for long-lasting relief of foot and ankle pain. Intra-articular treatments such as corticosteroids, hyaluronic acid, platelet-rich plasma, bone marrow aspirate concentrate, and adipose-derived stem cells may improve HFOA symptoms.