Wang P, Li ZP, Ruan YH, Yan P, Fu WP, Zhang CJ. Optimization and advances in negative pressure wound therapy for the management of necrotizing fasciitis in the upper limb. World J Orthop 2025; 16(3): 105130 [PMID: 40124720 DOI: 10.5312/wjo.v16.i3.105130]
Corresponding Author of This Article
Chang-Jiang Zhang, MD, Chief Physician, Professor, Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, No. 3 Kangfu Qianjie, Erqi District, Zhengzhou 450052, Henan Province, China. changjiangzhang1968@outlook.com
Research Domain of This Article
Orthopedics
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Peng Wang, Yu-Hua Ruan, Wei-Ping Fu, Chang-Jiang Zhang, Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Peng Yan, Third Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Co-first authors: Peng Wang and Zhi-Peng Li.
Co-corresponding authors: Wei-Ping Fu and Chang-Jiang Zhang.
Author contributions: Wang P and Li ZP conceptualization and writing of the original draft, reviewed and summarized the literature and wrote the first draft of the paper; Ruan YH and Yan P formal analysis and validation; Fu WP and Zhang CJ conceptualization, writing, reviewing and editing. All authors participated in drafting the manuscript and all have read, contributed to, and approved the final version of the manuscript.
Supported by Henan Province Key Research and Development Program, No. 231111311000; Henan Provincial Science and Technology Research Project, No. 232102310411; Henan Province Medical Science and Technology Key Project, No. LHGJ20220566 and No. LHGJ20240365; Henan Province Medical Education Research Project, No. WJLX2023079; and Zhengzhou Medical and Health Technology Innovation Guidance Program, No. 2024YLZDJH022.
Conflict-of-interest statement: No author has stated that there are any commercial, professional, or personal conflicts of interest relevant to the study, proving that it complies with the principles of publishing ethics.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chang-Jiang Zhang, MD, Chief Physician, Professor, Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, No. 3 Kangfu Qianjie, Erqi District, Zhengzhou 450052, Henan Province, China. changjiangzhang1968@outlook.com
Received: January 13, 2025 Revised: January 25, 2025 Accepted: February 17, 2025 Published online: March 18, 2025 Processing time: 58 Days and 23.1 Hours
Core Tip
Core Tip: This study explores the optimization of negative pressure wound therapy (NPWT) for the management of upper limb necrotizing fasciitis (NF), a life-threatening condition. It highlights the advantages of NPWT in accelerating wound healing and improving functional outcomes while addressing its limitations. Key innovations discussed include adaptive NPWT with dynamic pressure regulation, adjunctive therapies such as platelet-rich plasma and antimicrobial dressings, and the integration of advanced technologies like artificial intelligence, imaging modalities, and biomaterials. The findings emphasize the importance of personalized, multidisciplinary approaches and emerging technologies in enhancing treatment efficacy and global standardization of care for NF.
